4 results about "OI - Osteogenesis imperfecta" patented technology

The invention discloses a novel extensible long intramedullary rod and a matched tool, and relates to the technical field of medical instruments, the novel extensible long intramedullary rod comprises a female rod and a male rod, one end of the female rod is provided with a fixed tip, the other end of the female rod is provided with a blind hole, the male rod is sleeved with the blind hole, the fixed tip is used for being connected with the epiphysis of the far end of a long bone, and the end of the male rod is flush with an implantation opening. And the length of the male rod sleeved into the female rod is at least 1 / 2 of the length of the female rod. The extensible long intramedullary rod can effectively fix a long bone, prevent fracture of the long bone and maintain the shape of the long bone, can gradually achieve the purpose of extension along with the growth of the bone, can better maintain the mechanical axis of the bone, has a stronger protection effect on the fracture end, is particularly suitable for being applied to special patients in the department of orthopedics of children, and has a wide application prospect. And intraoperative and postoperative protection of lower limb long bone malformation and fracture caused by osteogenesis insufficiency and congenital long bone artificial joints can be realized.

The invention features polypeptides that include an extracellular ActRIIB variant. In some embodiments, a polypeptide of the invention includes an extracellular ActRIIB variant fused to an Fc domain monomer or moiety. The invention also features pharmaceutical compositions containing said polypeptides and methods of using the polypeptides to treat diseases and conditions including neuromuscular diseases, osteogenesis imperfecta, myelofibrosis, thrombocytopenia, neutropenia, and metabolic disease.

The invention provides a telescopic intramedullary nail system, and belongs to the technical field of medical instruments. Comprising a front bone body, a rear bone body and a limiting mechanism, a fixing sleeve is slidably connected to the inner wall of a fixing groove, a sliding rod is slidably connected to the inner wall of the fixing sleeve, and a connecting sleeve is slidably connected to the inner wall of one end of the fixing sleeve; the device is characterized in that the inner wall of the fixing sleeve is provided with a limiting mechanism for preventing the sliding rod from moving backwards; along with the growth of the front bone body and the rear bone body, the overall length of the front bone body and the rear bone body can be changed, meanwhile, the sliding rod and the fixing sleeve slide relatively through the connecting sleeve, the overall length is increased, joint growth with the bone is achieved, and the sliding rod and the fixing sleeve placed in the front bone body and the rear bone body can form the effect of an intramedullary nail. The bone fracture stabilizer can be used for preventing or stabilizing bone fractures or correcting deformity of long bones in the growth process so that patients suffering from osteogenesis imperfecta, skeletal dysplasia and other skeletal deformity can use the bone fracture stabilizer conveniently.

The present invention aims to provide a safe mattress which prevents the osteogenesis imperfecta patient from pressing the arm to fracture when turning over. The safe mattress comprises a bottom plate and a top plate, a longitudinal beam in the middle of the top wall of the bottom plate in the front-rear direction, the top plate is hinged at the top end of the longitudinal beam in the middle of the bottom wall, and the top plate is turned over around the top end of the longitudinal beam when one side of the top plate is pressed to turn over downward. The patient sleeps on the safe mattress in a supine position, and if the patient turns over to the left side, the weight of the body will mainly press on the left side of the top plate, the left side of the top plate will turn over downward, the longitudinal beam will make the right side of the top plate turn up to support the right side of the back of the patient, and the right side of the top plate will share part of the weight of the body for the left arm of the patient, so that the left arm is not easy to fracture. The patient turns over to the right side, and the same principle applies, which is not described here.