33 results about "Sub clinical" patented technology

The present invention includes compositions, kits and methods useful for the detection of mastitis in an animal. These agents and methods are primarily directed to a method of detecting the presence of mastitis, including sub-clinical mastitis, in cows, involving incubating a sample of milk from the cow with an agent that binds to lactoferrin such as, e.g., a monoclonal antibody specific for lactoferrin, and then detecting bound lactoferrin. The invention includes lateral-flow immunoassay methods and devices for assessing the presence of lactoferrin in milk samples.

The invention provides a method for detection of inflammatory disease in a subject that comprises assaying a test sample of peripheral blood from the subject for a marker of DNA damage. An elevated amount of marker present in the test sample compared to control sample is indicative of inflammatory disease activity, including sub-clinical inflammation. The method can be adapted for quantitatively monitoring the efficacy of treatment of inflammatory disease in a subject. Markers of DNA damage include single- and/or double-stranded breaks in leukocytes, oxidative DNA damage in leukocytes, or a marker of nitric oxide oxidative activity (protein nitrosylation in leukocytes). The inflammatory disease can be inflammatory bowel disease (ulcerative colitis or Crohn's disease). The invention may also be used for detection of other types of inflammatory disease, such as non-immune intestinal inflammatory disease (diverticulitis, pseudomembranous colitis), autoimmune diseases (rheumatoid arthritis, lupus, multiple sclerosis, psoriasis, uveitis, vasculitis), or non-immune lung diseases (asthma, chronic obstructive lung disease, and interstitial pneumonitis). This unexpected discovery of markers of genotoxicity present in circulating leukocytes enables detection of inflammation occurring at a localized site with a relatively simple and minimally invasive assay using peripheral blood.

The invention provides a method and assay kits for detecting keratoconus, including sub clinical keratoconus, in a specimen. The method comprises assaying a specimen of corneal epithelium for the presence of an expression product of the AQP5 gene. The invention further provides a novel gene, KC6, that exhibits cornea-specific expression, as well as KC6-related molecules.

A device, system, and method employ spectrometry to interrogate udder tissue or milk to diagnose clinical and sub-clinical mastitis.

The present invention relates to a dairy cow sub-clinical ketosis diagnosis test paper which belongs to the art of the veterinary clinical laboratory science. The present invention comprises a support cushion and a test cushion that is fixed on the support cushion; and the present invention is characterized in that the test cushion of the test paper comprises the following reagents: D-(-)-3-Hydroxybutyrate Dehydrogenase with 2270U/mg and 50mg-100mg; nicotinamide adenine dinucleotide with 300mg-500mg; diaphorase with 35U/mg-45U/mg and 500-1,000mg; NBT with 100mg-200mg; Tris Base with molecular weight 121.14 and 1.21g; oxalic acid with molecular 126 and 126mg; fucose with molecular 383 and 4-6g; and distilled water with 100ml. The dairy cow sub-clinical ketosis diagnosis test paper of the present invention is used conveniently and has the advantages of economic practicality, high sensitivity and specificity, and good stability. The test paper is used to test D-(-)-3-Hydroxybutyrate and D-(-)-3-Hydroxybutyrate sodium in the milk of the milch cow.

The present invention relates to the use of an immunogenic composition comprising a porcine circovirus type 2 (PCV2) antigen for the prevention and treatment of sub-clinical PCV2 infection in animals, preferably in pigs.

This invention is directed to methods, kits and compositions for the diagnosis and treatment of conditions associated with sub-clinical inflammatory conditions such as diabetes mellitus.

Mastitis in a milking animal is detected through sensing the capacitance effects in milk. Using frequencies of greater than 60 megahertz applied by a capacitance probe to milk as it streams through otherwise conventional milking equipment during milking, yields a reliably discernable shift in the phase angle, indicating the presence of mastitis.

The invention discloses a veterinary drug composition (Guiqisu) capable of enhancing immunity, which is composed of effective component or acceptable carriers on effective component and pharmacy, wherein the effective component is prepared by astragalus membranaceus submicron powder and angelica extract. The drug composition has the effects of replenishing qi and nourishing blood and regulating double immune; the drug composition is used for treating postpartum blood deficiency weak of dam, immune system damage caused by animal virus infection, immune antibody disorder, weak anti-stress ability in laying fastigium of poultry, and weak poultry caused by diseases, and specifically the drug composition is suitable for poultry with low immunity in a sub-clinical state. The invention further discloses a preparation method of the drug composition.

The invention relates to a method for determining udder health characteristics in bovine subjects, wherein udder health characteristics comprise sub-clinical and clinical mastitis. In particular, the method of the invention involves identification of genetic markers and/or Quantitative Trait Locus (QTL) for the determination of udder health characteristics in a bovine subject. The determination of udder health characteristics involves resolution of the specific microsatellite status. Furthermore, the invention relates to a diagnostic kit for detection of genetic marker(s) associated with udder health. The method and kit of the present invention can be applied for selection of bovine subjects for breeding purposes. Thus, the invention provides a method of genetically selecting bovine subjects with udder health characteristics that will yield cows less prone to mastitis.

A method including sensing local accelerations or changes in sensor position, including orientation and displacement, with a local acceleration sensor mounted on a chest or abdomen of a patient, and calculating energy of polyphasic motions, based on sensed information of the local acceleration sensor and classifying severity of cardiac decompensation by calculating an excessive energy index (EEi) that compares excessive energy that appears in the polyphasic motions to energy required for inspiration at a basic respiratory rate.

The invention relates to a nutrition complementing method for repairing cell disorder and medicine recipe for same. The cells are the foundation of human body texture structure. As long as the metabolism of the cells function normally, the human texture structure and function are normal, the human body can keep healthy. If disease preventive measures can be taken by applying the recipe and method, a satisfactory result can be achieved. Therefore, through the most reasonable proportioning of medicines and the control of taking time and taking amount, the sub-health and sub-clinical conditions can be prevented from the root of the cell metabolism, thus preventing and treating most chronic diseases.

The invention discloses application of resveratrol to preparing medicines for treating sub-clinical hypothyroidism and neuropsychiatric syndromes due to the sub-clinical hypothyroidism. The application has the advantages that the resveratrol is applied to preparing the medicines for treating the sub-clinical hypothyroidism and the neuropsychiatric syndromes due to the sub-clinical hypothyroidism, accordingly, imbalance hypothalamus-pituitary-thyroid axis functions of sub-clinical hypothyroidism patients can be improved, the learning and memory ability of the sub-clinical hypothyroidism patients can be enhanced, and depression-related behavior of the sub-clinical hypothyroidism can be improved.