31results about How to "Convenient IV" patented technology

The invention provides a paramagnetic metal complex functionalized fluorogold nano-cluster magnetic resonance and fluorescence imaging contrast agent. The invention relates to the field of magnetic resonance imaging and fluorescence imaging contrast agents. With the contrast agent provided by the invention, problems of existing contrast agents of low relaxation efficiency, high toxicity, low tissue organ selectivity and fast in-vivo metabolism can be solved. According to the invention, ethylenediaminetetraacetic acid (EDTA) or diethylene triaminepentaacetic acid (DTPA) are connected to folic-acid-modified bovine serum albumin fluorogold nano-clusters through amide bonds; and EDTA or DTPA is respectively coordinated with paramagnetic metal ions, such that the complex is obtained. With the contrast agent provided by the invention, the relaxation efficiency can reach 23.7mM<-1>*s<-1>. The contrast agent has an advantage of low toxicity. According to the invention, high spatial resolution of magnetic resonance imaging and high sensitivity of fluorescence imaging are combined. Therefore, the contrast agent provided by the invention can be used in magnetic resonance imaging and fluorescence imaging.

The invention provides a paramagnetic metal complex and a synthetic method and application thereof. The paramagnetic metal complex is an arabinogalactan-modified 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacethyl paramagnetic metal complex. A magnetic resonance imaging contrast agent prepared from the paramagnetic metal complex has high stability, water solubility and relaxation rate and is targeted to liver and kidney, so that targeted imaging is realized, and the imaging contrast and definition are improved. The paramagnetic metal complex has a good effect on raising the early diagnosis levels of diseases of liver and kidney organs, is about 2 times the relaxation rate of dotarem, has very long targeted radiography imaging time, can be easily prepared into a solution with required concentration for intravenous injection, is suitable for sterilizing and disinfecting with a hot pressing method, can be selectively identified by an asialoglycoprotein receptor on a liver parenchyma surface, and has high selectivity on livers of human beings or other mammals.

The invention discloses a portable anesthesia device for an anesthesia department, and relates to the technical field of anesthesia devices. The portable anesthesia device comprises an outer frame, ahorizontal plate is fixedly connected on the right side of the outer frame, an infusion device is fixedly connected at the top of the horizontal plate, a side plate is fixedly connected on the left side of the outer frame, an oxygen infusion device is fixedly connected at the top of the side plate, and a working table is fixedly connected at the top of the outer frame. According to the portable anesthesia device, anesthesia drugs are conveniently and intravenously injected into a patient, the patient is narcotized, the height of an injection frame can be adjusted according to requirements, theportable anesthesia device is simple to operate and convenient to use, so that the patient more smoothly breathes, the stability of a body function of the patient is ensured, vibration applied to thedevice is reduced, the stability of the device is improved, accidents are prevented, a narcotizing process is conveniently controlled by medical staff, body information of the patient is convenientlyobserved by the medical staff, and unforeseen circumstances are prevented.

The invention provides a diamino polyethylene glycol modified paramagnetic metal complex magnetic resonance imaging contrast agent, and aims at solving the problems of low relaxation rate, high toxicity and large dosage of a contrast agent in the prior art. The contrast agent is prepared by the following steps: reacting 1,4,7,10-tetrazacyclododecane-1,4,7,10-tetraacetic acid compound with diaminopolyethylene glycol with different molecular weights; preparing a macromolecular ligand through an amidation reaction; and forming a paramagnetic metal complex with paramagnetic metal elements Sc, Ti, V, Mn, Cu, Mo, Ru, Fe or positive trivalent or divalent ion of lanthanide rare-earth elements. The contrast agent has the advantages of high stability, water solubility, relaxation rate and small dosage.

An injection of water-soluble 17-allylamino-17-demethoxy geldanamycin (17-AAG) for treating multiple kinds of cancers is prepared from 17-AAG and polyethanediol for increasing the solubility of 17-AAG in water.

The invention discloses an aspartate-leucine copolymer modified paramagnetism metal complex as well as a preparation method and application thereof, belongs to the technical field of contrast agents, and solves the technical problems in the prior art that a magnetic resonance contrast agent is lower in targeting and high in dosage so as to further improve the relaxation efficiency, imaging contrast ratio, definition and sensitivity of the contrast agent. The structural formula of the metal complex is shown in the formula I (refer to the description), wherein z is an integer ranging from 1 to 1000, x is an integer ranging from 1 to 1000, y is an integer ranging from 1 to 1000, and M<m+> refers to paramagnetism metal ions. The metal complex can be used as a magnetic resonance imaging contrast agent which has excellent stability, water-solubility and relaxation efficiency, also has excellent targeting to a liver, and is higher in imaging contrast ratio and definition; the dosage lower limit of the metal complex is only 0.001 mmol/kg.

The invention relates to a heating and pressurizing infusion set, and relating to an infusion set. The invention aims to solve the problem that in the process of intravenous guttae, a medicine bottle can not be hung without an infusion support, and the problem that during the intravenous injection, the temperature of the liquid medicine is the storage temperature which is always lower than the temperature of human body in frigid climate, thus during the liquid medicine is injected, negative effect on the patient is always generated because of the undercooling liquid medicine, and the problem that during the transfusion, the patients need to sit and lie down, which influences the movement. The outer wall of the packet body of the invention is provided with a heating metal wire interface connected with heating metal wire; one end of wire is connected with a circuit board; the other end of the wire is connected with an air pump; the outlet of the air pump is connected with the inlet of an air bag; the outlet of the air bag is connected with the interface for inserting the medicine bottle; the air bag, the interface for inserting medicine bottle and the air pump are all arranged in the bottom of the packet; and the bottom of the packet is provided with the outlet of an infusion tube. The invention can achieve zero error output, can be repeatedly used, saves resources, and can transfuse at hospital, at home or in the way.

The invention discloses a pneumatic device for intravenous infusion, relates to a pneumatic device and aims to solve the problems that the conventional intravenous infusion needs an infusion bottle bracket for hanging an infusion bottle, which is inconvenient for a patient who needs to move. A spring and a plug are arranged inside a spring seat; an opening baffle sheet is fixed at the outermost end of the spring seat; and a sealing gasket is fixed on the inner side of the opening baffle sheet and is matched with the plug. A cylinder is fixed on a base; an overhead valve is fixed on the base inside the cylinder; a plastic gasket base is fixed on an outer wall of the overhead valve; a plastic gasket is arranged on the plastic gasket base; one end of an air outlet adapter is communicated with the overhead valve; internal threads are formed on an inner wall of the cylinder; and the internal threads of the cylinder are matched with external threads of a tank body. The pneumatic device has the inflation pressure of 0.6 to 1 MPa and the inflation capacity of 500 to 600 cubic centimeters, can be used for 2,000ml of liquid medicine for intravenous infusion, and has the advantages of convenient carrying, high safety, easy disinfection and convenient replacement.

The invention provides a paramagnetism metal complex magnetic resonance imaging contrast agent containing asparaginic acid-glucan and a preparation method of the contrast agent, to solve the problem that in the prior art the contrast agent is low in relaxation rate. According to the contrast agent, the glucan is used as a carrier; asparaginic acid is connected with 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA), and is further subjected to coordination with the paramagnetism metal ions in a mole ratio of 1:1 so as to obtain the complex. According to the preparation method of the paramagnetism metal complex magnetic resonance imaging contrast agent containing the asparaginic acid-glucan, the contrast agent with relatively higher relaxation efficiency is obtained by controlling the dosage ratio of reaction raw materials, the pH value of solution, the reaction temperature and the reaction time. The contrast agent can be used for magnetic resonance imaging; after the contrast agent imaging is accomplished, the asparaginic acid carried in the contrast agent has protection function on hearts, and therefore the contrast agent is an imaging contrast agent with double functions.

The invention provides a practical patient garment. The practical patient garment with two sleeves is mandarin, zippers with double sliders are arranged on the two sleeves and at the 2/3 cutting and sewing positions on front pieces of the patient garment, and a pull ring is arranged at each of sleeve ends and front piece ends when each zipper is zipped up. Another two zippers with double sliders are arranged on the outer sides of two sleeve elbows, and two pull rings are arranged at two ends of each zipper respectively when each zipper is zipped up. The practical patient garment is simple to manufacture as the zippers with the double sliders are arranged on the two sleeves and at the 2/3 cutting and sewing positions on the front pieces of the patient garment without adding processing processes. Besides, the practical patient garment can bring convenience to patients and is convenient for nurses to perform intravenous injection for the patients.

The invention provides a paramagnetic metal complex using an aspartic acid-isoleucine copolymer as a carrier, a preparation method of the paramagnetic metal complex and a magnetic resonance imaging contrast agent, and belongs to the field of the magnetic resonance imaging contrast agent, in order to solve the technical problems of a contrast agent in the prior art which is relatively low in liver identification, short in imaging time and not high in relaxivity. The complex takes the aspartic acid-isoleucine copolymer as a carrier and is connected with a ring-shaped 1,4,7,10-tetraazacycl ododecane-1,4,7,10-tetraacetic acid ligand on a side chain of the carrier, and the structure of the complex is as shown in formula (I). The invention also provides a preparation method of the paramagnetic metal complex using the aspartic acid-isoleucine copolymer as a carrier. The invention also provides a magnetic resonance imaging contrast agent which is prepared from the paramagnetic metal complex using the aspartic acid-isoleucine copolymer as a carrier. The contrast agent disclosed by the invention has good selectivity for livers of human bodies or other mammals.