51results about How to "Improved and efficient" patented technology

Improved techniques are provided for processing authorization requests. In some embodiments, an authorization request specifying a hierarchical resource can be processed without having to sequentially process the various security policies configured for a collection of resources.

A backflow preventing check valve for use in a fan unit in a forced air cooling system includes a generally rectangular frame, a plurality of adjacent parallel pivot axes mounted in the frame, and a plurality of adjacent vanes that pivot around the axes between open and closed positions. The axes extend generally transverse to the direction of fluid flow through the valve, and each axis is offset from the center of gravity of its associated vane so that fluid flowing through the valve in an allowed direction moves the vanes toward the open position, and fluid flowing in a blocked direction moves the vanes toward the closed position. The axes are inclined at an angle (α) measured from a vertical reference, thereby causing the vanes to be urged by gravity to pivot towards the closed position.

An apparatus and method for controlling and providing off-pitch shifting circuitry for implementing column redundancy in a multiple-array memory is described in connection with an on-board cache memory integrated with a microprocessor. Depending upon the particular sub-array being accessed, shift position data is provided to a shared, off-pitch shift circuit to control the read and / or write operations for the memory. A register bank stores data identifying the defective columns which is compared to the incoming address information to detect any matches. In response to a match, control information is provided to the off-pitch shift circuit for shifting or re-routing the incoming data to a non-defective address in the memory. In this way, defective columns located in different positions in each sub-array can be replaced by redundant paths, thereby repairing the cache and increasing the manufacturing yield of microprocessors with an on-board cache memory.

Methods and systems for evaluating the electrical activity of the heart to identify novel ECG patterns closely linked to the subsequent development of serious heart rhythm disturbances and fatal cardiac events. Two approaches are describe, for example a model-based analysis and space-time analysis, which are used to study the dynamical and geometrical properties of the ECG data. In the first a model is derived using a modified Matching Pursuit (MMP) algorithm. Various metrics and subspaces are extracted to characterize the risk for serious heart rhythm disturbances, sudden cardiac death, other modes of death, and all-cause mortality linked to different electrical abnormalities of the heart. In the second method, space-time domain is divided into a number of regions (e.g., 12 regions), the density of the ECG signal is computed in each region and input to a learning algorithm to associate them with these events.

A method of manufacturing a plurality of secondary containment panels and assembling and installing the panels in a secondary containment system of an above-ground liquid storage tank or other retention facility includes forming a plurality of flexible substrate pieces. A liquid impermeable coating is applied to the upper surface of each piece such that an edge segment of the piece remains uncoated. The coating is applied to the substrate piece in an indoor enclosure. The coated pieces are delivered to the site of the tank and extended across the ground adjacent to the tank. At least a pair of the pieces are juxtaposed relative to one another such that a first one of the pieces overlaps the uncoated segment of the second piece to form a seam. An adhesive substance is then applied to the seam to fasten the first and second pieces together.

An aquaculture system for cultivation, containment and rearing of various mollusks, particularly abalone, which includes a habitat which supports a plurality of molded panels including openings for communicating between adjacent panels, whereby food is available throughout the habitat. An outer netting or open structure which allows water to flow through the habitat, but protects the mollusks from predators, while still containing the food and permitting the flow of water therethrough, selected ones of said panels being configured to provide buoyancy for the habitat which is tethered from the bottom of the ocean.

A system and method for automatically adjusting medical displays is arranged to communicate medical information to a caregiver. The system includes at least one display for displaying medical information, a wireless communication device associated with the display and a wireless communication device associated with the caregiver. The wireless communication device associated with the display is arranged to realize if the wireless communication device associated with the caregiver, and thus the caregiver, is present in a predetermined area near the display. A controller associated with the display is arranged to automatically adjust at least one characteristic of the display based upon the realized presence of the caregiver. According to the method, the presence of the caregiver is detected when the caregiver enters the predetermined area near the display. At lease one characteristic of the display is thus adjusted automatically based upon the detected presence of the caregiver in the predetermined area.

A lid for a container forming an upper rim portion. The lid comprises a central portion and a peripheral skirt portion forming a downwardly disposed channel extending around the periphery of the lid. The channel is adapted to overlie the container upper rim portion and to hold a sealing gasket therein at an upper portion of the channel. The skirt portion forms a plurality of bendable flaps extending within said channel, each of which being movable from a first position wherein each said flap extends across a portion of said channel preventing said gasket from falling out of the channel to a second position wherein each said flap is positioned within a relief pocket formed within said skirt wall. Each flap is urged from said first position to said second position by the rim of the container as it is inserted within said channel and pressed into engagement with said gasket. The flap may be inserted in a clearance fit within said pocket and remains in said pocket once urged therein by said rim portion. Alternately each flap may be pressed into friction fit engagement within said pocket and is fixed within said pocket once pressed therein.

Devices and methods for optically scanning an in-vivo lumen, and for determining contact between an in-vivo device and an in-vivo lumen wall. The device may include an elongated housing having a cylindrical portion. At least one illuminating body may provide illumination at the circumference of the cylindrical portion, and at least one light sensor may sense light that penetrated and was scattered from the tissue of the in vivo lumen. The device may include means for preventing direct illumination from the illuminating body from reaching the light sensor and for decreasing the amount of direct light reflection from the outer surface of the in vivo lumen onto the light sensor.

Provided herein are methods and kits for the improved detection of rare mutations within a high background. Exemplary embodiments relate to kits and methods that include amplification primers, a blocking oligonucleotide, and one or more allele-specific detector probes, useful in the specific detection of rare allelic variants or mutations.

A method of manufacturing a plurality of secondary containment panels and assembling and installing the panels in a secondary containment system of an above-ground liquid storage tank or other retention facility includes forming a plurality of flexible substrate pieces. A liquid impermeable coating is applied to the upper surface of each piece such that an edge segment of the piece remains uncoated. The coating is applied to the substrate piece in an indoor enclosure using a computer controlled robotic sprayer that applies a uniform coating. Metal plates are embedded in the floor used for quality control testing of the coating thickness using magnetic gauges. At least a pair of the pieces are juxtaposed relative to one another such that a first one of the pieces overlaps the uncoated segment of the second piece to form a seam.

Improved techniques are provided for processing authorization requests. In some embodiments, an authorization request specifying a hierarchical resource can be processed without having to sequentially process the various security policies configured for a collection of resources.

The invention relates to a method for enriching a target polynucleotide sequence containing a genetic variation said method comprising: (a) providing two primers targeted to said target polynucleotide sequence; (b) providing a target specific xenonucleic acid clamp oligomer specific for a wildtype polynucleotide sequence; (c) generating multiple amplicons using PCR under specific temperature cycling conditions; and (d) detecting said amplicons.

Client position in a multi-client game is determined using dead reckoning. Clients send information to a server over a network. The server distributes this information to other clients. A client uses this information and dead reckoning to determine a character's position. The server may calculate the client's position using dead reckoning and send updates to clients when errors between actual and calculated positions exceed a threshold. Clients may calculate their position according to dead reckoning, and when an error between actual and calculated position exceeds a threshold, send updated information to other clients. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules that allow a reader to quickly ascertain the subject matter of the disclosure contained herein. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims.

An aquaculture system for cultivation, containment and rearing of various mollusks, particularly abalone, which includes a habitat which supports a plurality of molded panels including openings for communicating between adjacent panels, whereby food is available throughout the habitat. An outer netting or open structure which allows water to flow through the habitat, but protects the mollusks from predators, while still containing the food and permitting the flow of water therethrough, selected ones of said panels being configured to provide buoyancy for the habitat which is tethered from the bottom of the ocean.

The enterprise database system provides methods, data, and user interfaces for performing reassessments and creating financial and accounting disclosure reports. Data fields for entities are monitored for changes that are evident at the end of reporting periods and may trigger the need to reassess the categorization of the entity. The system receives a request to perform a reassessment based on changes to particular data fields during the reporting period. The system retrieves entities that require reassessment based on the trigger events applicable to the entities. A reassessment is performed for each of the entities having a trigger event and the reassessment is stored in a historical database. Based on the reassessment, the system generates prompts to re-categorize the reassessed entity. Following the reassessment and categorization, the system can generate a disclosure report that presents information about the newly categorized entity.

The present invention relates to a method of verifying a measurement accuracy of a level gauge system. The method comprises determining a first measurement value indicative of a time-of-flight of a first electromagnetic reflection signal to a reference reflector and back; determining a measurement unit verification measurement value based on a response signal from a verification arrangement; determining a second measurement value indicative of a time-of-flight of a second electromagnetic reflection signal to the reference reflector and back; and determining a verification result based on the first measurement value, the second measurement value and the measurement unit verification measurement value. Through embodiments of the present invention, it will be verified that the measurement unit is functioning correctly and that level gauge system works as it should also after being reconnected to the propagation device.

Improved techniques are provided for processing authorization requests. In some embodiments, an authorization request specifying a non-hierarchical resource can be processed without having to sequentially process the various security policies configured for a collection of resources.

The present invention relates to a method of verifying a measurement accuracy of a level gauge system. The method comprises determining a first measurement value indicative of a time-of-flight of a first electromagnetic reflection signal to a reference reflector and back; determining a measurement unit verification measurement value based on a response signal from a verification arrangement; determining a second measurement value indicative of a time-of-flight of a second electromagnetic reflection signal to the reference reflector and back; and determining a verification result based on the first measurement value, the second measurement value and the measurement unit verification measurement value. Through embodiments of the present invention, it will be verified that the measurement unit is functioning correctly and that level gauge system works as it should also after being reconnected to the propagation device.

The present invention relates to an improved and efficient method for simultaneous monitoring of abundance of individual mutants of a microbe in mixed populations where insertion of a known transposon in the genome of a microbe such that each mutant caries a single transposon insertion, isolating the genomic DNA of the mixed population of mutants, fragmenting the same with a frequently cutting restriction enzyme, ligating a double standard adapter to the genomic DNA fragments, amplifying the DNA fragments adjoining transposon insertions thereby generating a set of DNA fragments corresponding only to mutated genes resolving the said amplified DNA fragments followed by comparing the intensity of DNA fragments obtained from population of mutants before selection with that obtained from the population subjected to selection and finally sequencing the DNA fragments that change in abundance to identify the mutated genes.

In a pultrusion method for manufacturing a fibre-reinforced composite product comprising reinforcing fibres embedded in a thermoplastic matrix material, the following is performed along a path of pultrusion: providing a preform; further downstream, inductively heating the preform to a processing temperature of the thermoplastic matrix material; and, further downstream, introducing the preform into a die and consolidating the preform by means of the die while the preform passes through the die.

The invention relates to a method for enriching a target polynucleotide sequence containing a genetic variation said method comprising: (a) providing two primers targeted to said target polynucleotide sequence; (b) providing a target specific xenonucleic acid clamp oligomer specific for a wildtype polynucleotide sequence; (c) generating multiple amplicons using PCR under specific temperature cycling conditions; and (d) detecting said amplicons. We introduce a novel molecule, Xenonucleic Acid (XNA) for the NGS library preparation. XNA is able to selectively suppress amplification of DNA with wild type alleles and amplify DNA containing mutant alleles. Mutants with low allelic frequency will be easily detectable without deep sequencing after enrichment by adding XNA in multiplex PCR. The 17 actionable mutants related to lung or colorectal cancer diseases at different variant allelic frequency (VAF)% were investigated. Clinical sensitivity is significantly improved with XNA in various types of samples.

An improved and efficient punch press comprising a unique assembly of adjustable and interchangeable components to offer a device that is versatile in its applications.

An annular guide ring for controlling the position of at least one of rolling elements and a bearing cage in relation to an inner ring of a rolling bearing. The guide ring comprises a base portion, a first side portion extending in a radial direction from a first axial end portion of the base portion, and a second side portion extending in a radial direction from a second axial end portion of the base portion, wherein the first side portion and the second side portion are integrally formed with the base portion of a one-piece sheet material. Also described is a method for manufacturing the guide ring for the rolling bearing.

A system and method for automatically adjusting medical displays is arranged to communicate medical information to a caregiver. The system includes at least one display for displaying medical information, a wireless communication device associated with the display and a wireless communication device associated with the caregiver. The wireless communication device associated with the display is arranged to realize if the wireless communication device associated with the caregiver, and thus the caregiver, is present in a predetermined area near the display. A controller associated with the display is arranged to automatically adjust at least one characteristic of the display based upon the realized presence of the caregiver. According to the method, the presence of the caregiver is detected when the caregiver enters the predetermined area near the display. At lease one characteristic of the display is thus adjusted automatically based upon the detected presence of the caregiver in the predetermined area.

The present invention is related to an improved and efficient process for preparation of (3R,4R)-(1-benzyl-4-methylpiperidin-3-yl)-methylamine which comprises:(a) N-acylation of 3-Amino-4-methyl pyridine; (b) Quarternization of 3-Acetylamino-4-methyl pyridine using benzyl halide; (c) Partial reduction of quarternized 3-Acetylamino-4-methyl pyridine by Sodium borohydride in Methanol or water; (d) Hydrolysis of partially reduced product to 1-Benzyl-4-methylpiperidin-3-one in presence of acid; (e) Reductive amination of 1-Benzyl-4-methylpiperidin-3-one using Methanolic methylamine in presence of Titanium(IV) isopropoxide in Methanol; (f) Resolution of 1-Benzyl-4-methylpiperidin-3-yl)-methylamine using Ditoluoyl (L) tartaric acid to get (3R,4R)-(1-benzyl-4-methylpiperidin-3-yl)-methylamine. The invention is also related to novel intermediates:wherein R, R′ and X are as described in the specification.

Improved techniques are provided for processing authorization requests. In some embodiments, an authorization request specifying a non-hierarchical resource can be processed without having to sequentially process the various security policies configured for a collection of resources.

The invention relates to a method for enriching a target polynucleotide sequence containing a genetic variation said method comprising: (a) providing two primers targeted to said target polynucleotide sequence; (b) providing a target specific xenonucleic acid clamp oligomer specific for a wildtype polynucleotide sequence; (c) generating multiple amplicons using PCR under specific temperature cycling conditions; and (d) detecting said amplicons. We introduce a novel molecule, Xenonucleic Acid (XNA) for the NGS library preparation. XNA is able to selectively suppress amplification of DNA with wild type alleles and amplify DNA containing mutant alleles. Mutants with low allelic frequency will be easily detectable without deep sequencing after enrichment by adding XNA in multiplex PCR. The 17 actionable mutants related to lung or colorectal cancer diseases at different variant allelic frequency (VAF) % were investigated. Clinical sensitivity is significantly improved with XNA in various types of samples.

A method for producing an annular-shaped cage for a rolling bearing assembly. The method comprises steps of: (a) providing a workpiece contained in a plane having a first side and a second side; (b) forming an annular-shaped cage from the workpiece, the annular-shaped cage having a U-shaped cross section such that portions of the first side of the workpiece face each other; and (c) forming a plurality of windows in the workpiece for receiving and positioning a set of rolling elements.

The present invention relates to a method of manufacturing a wind turbine blade comprising the steps of manufacturing a pressure shell halves and arranging a spar structure (62) within one of the shell halves. The spar structure (62) comprises two parts releasably coupled to each other. The method results in a segmented wind turbine blade for easy transportation and re-assembly.