237results about How to "Maintain resistance" patented technology

The invention relates to a pharmaceutical dosage form, preferably with controlled release of a pharmacologically active compound (A) contained therein, the pharmaceutical dosage form very preferably being tamper-resistant and most preferably having a breaking strength B1 of at least 500 N in direction of extension E1 and having a breaking strength B2 of less than 500 N in direction of extension E2.

The invention describes compounds, compositions and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

The present invention describes compounds, compositions and methods of using the same comprising lysine covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

A quasi-kinematic coupling for mating components (mechanical parts, surfaces, assemblies and the like) employing mating sets of surface of revolution, (conical) grooves and cooperative surface of revolution (spherical / conical) protrusions for establishing six lines (not just prior points) of contact at the kinematic interfaces, and with elastic compliance therebetween and preferably with relief features to define the effective orientation as a clamping force seats the protrusions in the grooves and seals the component mating surfaces into contact.

The invention describes compounds, compositions and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

The invention relates to a pharmaceutical dosage form, preferably with controlled release of a pharmacologically active compound (A) contained therein, the pharmaceutical dosage form very preferably being tamper-resistant and most preferably having a breaking strength B1 of at least 500 N in direction of extension E1 and having a breaking strength B2 of less than 500 N in direction of extension E2.

A membrane electrode assembly for polymer electrolyte fuel cells comprises a cathode electrode, an anode electrode, and a polymer electrolyte membrane placed between these electrodes, and a catalyst material of Pt—Ru alloy is contained in the anode and the crystal of Pt—Ru alloy is mainly of a face-centered cubic structure.

The present invention describes compounds, compositions and methods of using the same comprising lysine covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

A portable information handling system with rotationally coupled housing portions having an OLED film display disposed over the housing portions automatically adapts presentation of visual images at the display to the housing portion relative positions and orientation. For example, based on a fold orientation of the housing and a landscape or portrait orientation, visual information adapts to show different user interfaces and content.

A multi-layer aluminum brazing sheet including a core layer, interliner, braze clad layer and a sacrificial layer, in which the post-braze strength of the brazing sheet is optimized by controlling the manganese (Mn), silicon (Si), copper (Cu) and magnesium (Mg) contents of the core layer and the Mn, Si and Cu content of the interliner and the Mn, Si and Zn content of the sacrificial layer and the specifics of the braze thermal cycle. The brazing sheet maintains corrosion resistance, while optimizing post-braze strength, by utilizing 0.5 wt. % to 1.2 wt. % Cu in the interliner. Further, the interliner and sacrificial layer of the brazing sheet contain low or no magnesium to maintain the brazing sheet's braze-ability.

The present invention provides a ferrite core which has a structure in that plating is prevented from elongating, which can maintain insulation resistance between electrodes and can prevent short-circuit between a conductor wire and the electrode without damaging adhesion properties while mounted and, moreover, which can stabilize a Q value (loss characteristic) of a product. The ferrite core includes a wound core and flanges integrally formed at both ends of the wound core, and each of the flanges includes a plurality of legs provided so as to rise from one surface of the wound core and having a top surface to be formed with electrode, and each leg is tapered off toward the top surface and an vertical corner portion formed between adjacent side faces thereof has a curved surface.

A cerebrospinal fluid shunt system comprises a brain ventricle catheter (15) to insert into the brain ventricle (21) so as to drain cerebrospinal fluid from the brain ventricle, a sinus catheter (18) to insert into the sinus sagittalis system (22) for feeding the cerebrospinal fluid into the sinus sagittalis system, a shunt body member (10) connected at one end thereof to said brain ventricle catheter and at another end thereof to said sinus catheter system to provide fluidic communication between said brain ventricle catheter (15) and said sinus catheter (18), and a flow restriction (16) defined within the shunt body member (10) to maintain a resistance to fluid flow of the shunt system of less than 8 mm Hg / ml / min, such as 2-7 or 4-6 and preferably about 5 mm Hg / ml / min. When the shunt system is implanted the shunt body member (10) is placed subcutaneously on top of the calvarium of a patient, behind the coronal suture on one of side of the sagittal suture. One end of each of the catheters (15, 18) is then connected to a respective end of the shunt body member (10), and a second end of each catheter is inserted in the right ventricle (21) and in the sinus sagittalis system (22), respectively, via holes bored in the scull (19).

Provided are a phase-change memory device and method that maintains a resistance of a phase-change material in a reset state within a constant resistance range. In the method, data is provided to a first phase-change memory cell and then it is first determined whether data stored in the first phase-change memory cell and the data provided to the first phase-change memory cell are identical. If the data stored in the first phase-change memory cell and the data provided to the first phase-change memory cell are not identical, a complementary write current is provided to the first phase-change memory cell and it is second determined whether the data stored in the first phase-change memory cell and the data provided to the first phase-change memory cell are identical. If the data stored in the first phase-change memory cell and the data provided to the first phase-change memory cell are identical, data is provided to a second phase-change memory cell.

An antiglare-treated article comprising an acrylic resin substrate and a fluorine-containing polymer coating formed on the surface of the substrate, wherein the thickness of the coating is in the range between 0.03 and 0.5 mum, and the fluorine-containing polymer has a refractive index in the range between 1.30 and 1.40 and comprises a block which is compatible with the acrylic resin and a block comprising a fluorine-containing elastomer. This treated article can be stably produced at low costs although it has the same abrasion resistance and antiglare effects as those of conventional antiglare-treated articles, or it has better antiglare effects than conventional antiglare films while maintaining abrasion resistance.

To provide an integrated thin-film solar cell that prevents deterioration of hotspot resistance and has a high output voltage.A thin-film solar cell module comprising: a thin-film solar cell string comprising a plurality of thin-film solar cell elements interconnected in series, each of the thin-film solar cell elements including a surface electrode, a photoelectric conversion layer, and a back surface electrode laminated in this order, the thin-film solar cell module being configured so that the number of stages n of the series connection of the thin-film solar cell elements in the thin-film solar cell string satisfies the following formula (1):n<Rshm / 2.5 / Vpm×Ipm+1  (1),wherein Rshm is the most frequent short-circuit resistance value of the thin-film solar cell elements;Vpm is an optimum operation voltage of the thin-film solar cell elements; andIpm is an optimum operation current of the thin-film solar cell elements.

A portable information handling system with rotationally coupled housing portions having an OLED film display disposed over the housing portions automatically adapts presentation of visual images at the display based upon detection of a peripheral keyboard placed on the display. For example, a peripheral keyboard biases into a predetermined position with magnetic attraction and a keyboard manager removes content from the display beneath the keyboard.

A light emitting diode (LED) apparatus with temperature control and current regulation functions is provided. The LED apparatus includes at least one LED die and at least one temperature control and current regulation (TCCR) device. The TCCR device is electrically connected between the LED die and a power source, and is placed within an effective temperature sensing distance of the LED die, so as to sense temperature changes of the LED die. The resistance of the TCCR device is proportional to the temperature in a range of 25° C. to 85° C., i.e., the resistance increases with temperature. Moreover, the resistance difference of the TCCR device between 50° C. and 80° C. is greater than or equal to 100 mΩ.

Resistance against simple power analysis is maintained while a smaller table is used. An IC card 100 decrypts encrypted information using elliptic curve calculation for calculating a point k*C by multiplying a point C on an elliptic curve E with a coefficient k that is a positive integer less that a prime p. The calculation of the point k*C is performed by adding a multiplication result obtained by multiplying a digit position (window) value w of the acquired coefficient k with the point C in a position corresponding to the digit position, and is performed with respect to all digit positions. When a non-negative integer t exists that fulfills a condition that the acquired digit value w_can be divided by 2t and cannot be divided by 2t+1, the multiplication includes adding a point obtained by multiplying a point Q with w / 2t.

A magnetic recording medium of a coated type being formed by coating magnetic paint, which is mixed with and dispersed by a magnetic powder and a resin and an additive, on a substrate, the magnetic powder comprises a magnetite (Fe3O4) powder of which a surface is stuck with powdered carbon black, wherein a sticking amount of the powdered carbon black is within a range of 1 to 20 weight % per the magnetite powder.

Improved 5xxx aluminum alloys and products made therefrom are disclosed. The new 5xxx aluminum alloy products may achieve an improved combination of properties due to, for example, the presence of copper. In one embodiment, the new 5xxx aluminum alloy products are able to achieve an improved combination of properties by solution heat treatment.

An electronic image into which an electronic watermark is to be embedded is divided into a plurality of image regions spatially, and pixels each having a property of being difficult to visually recognize a variation in a pixel value are extracted as adaptive pixels from each of the plurality of image regions. A variation between the pixel values of the adaptive pixels in one of the plurality of image regions and those of the adaptive pixels in an adjacent one of the plurality of image regions is produced, and the pixel values of the adaptive pixels of the plurality of image regions are varied in a time direction according to the value of an embedded bit set of the electronic watermark. An electronic-watermark-embedded image is then generated by making the variation in the pixel values of the adaptive pixels vary step by step at a boundary between the two of the plurality of image regions and / or in the time direction so that the variation makes a slow transition.

An electrostatic image developing toner including a toner particle (C), wherein the toner particle (C) has a structure in which a resin particle (A) containing at least a first resin (a) or a coated film (P) containing the first resin (a) is attached to a surface of a resin-containing particle (B) containing a second resin (b), and wherein the resin (b) includes a polyhydroxycarboxylic acid skeleton, and the resin (a) is a polyester resin containing a polybasic acid and a polyhydric alcohol.

Provided are corrosion resistant metallurgical powder compositions, corrosion resistant compacted articles prepared from metallurgical powder compositions, and methods of preparing the same. Corrosion resistant metallurgical powder compositions include as a major component, an iron-based powder and, as a minor component, alloy additives that include chromium, and carbon. Upon compaction and sintering, the iron-based powder and alloy additives form a dual phase alloy system. The dual phase alloy system is denoted by an admixed martensite and ferrite microstructure. This unique microstructure results in beneficial physical properties, such as for example, high strength, hardness, and ductility, impact energy, and fatigue endurance, while maintaining resistance to corrosion.

To provide a pneumatic tire achieving improved wear resistance and improved handling performance while maintaining rollover resistance, a tread surface 11 is formed of a center arc 31, a shoulder-side arc 32, and a shoulder arc 33. The tread surface 11 is formed such that a value given by F1=L1 / (TDW×0.5) falls in the range of 0.64≦F1≦0.7, a value given by F2=TR1 / OD falls in the range of 1.2≦F2≦2.0, a value given by F3=TR2 / TR1 falls in the range of 0.1≦F3≦0.2, and a value given by F4=(β×TDW) / (100×SW) falls in the range of 0.35≦F4≦0.48, where L1 is an outline range being a width from an equatorial plane 5 to an edge of the center arc 31, TDW is an extended tread width, TR1 is a curvature radius of the center arc 31, TR2 is a curvature radius of the shoulder-side arc 32, OD is a tire outside diameter, SW is a total width, and β is an aspect ratio.

An automated method of producing encoded images for incorporation into a digital document is provided. The method comprises receiving a request from a user to produce an encoded image. The request includes user-supplied data for producing the encoded image, the user-supplied data including user-supplied authentication indicia and / or at least one user-supplied encoding parameter. The method further comprises determining whether the user is authorized to produce an encoded image using the user-supplied data. Responsive to a determination that the user is authorized to produce an encoded image using the user-supplied data, encoding actions are carried out. The encoding actions include establishing at least one digitized authentication image and establishing an encoding parameter set including any user-supplied encoding parameters. The encoding parameter set is usable to encode one or more of the at least one digitized authentication image. The encoding actions also include encoding one or more of the at least one digitized authentication image using the encoding parameter set to produce a final encoded image.

A pneumatic tire having excellent balance between low fuel consumption and grip property and capability of suppressing crack generation in a tread groove bottom while maintaining abrasion resistance is provided. The pneumatic tire has a tread formed from a rubber composition includes per 100 parts by weight of a diene rubber containing a styrene-butadiene rubber, from 30 to 150 parts by weight of a reinforcing filler containing from 20 to 100 parts by weight of silica, and from 5 to 40 parts by weight of a carboxyl-terminally modified liquid polybutadiene, and further includes a silane coupling agent in an amount of from to 25 parts by weight per 100 parts by weight of the silica.

A dielectric ceramic composition, comprising a main component including barium titanate; a first subcomponent including at least one kind selected from MgO, CaO, BaO and SrO; a second subcomponent functioning as a sintering auxiliary agent; a third subcomponent including at least one kind selected from V2O5, MoO3 and WO3; a fourth subcomponent including an oxide of R1 (note that R1 is at least one kind selected from Sc, Er, Tm Yb and Lu); a fifth subcomponent including CaZrO3 or CaO+ZrO2; and an eighth subcomponent including an oxide of A (note that A is at least one kind selected from a cation element group having an effective ionic radius at the time of 6 coordination of 0.065 nm to 0.085 nm); wherein a ratio of the eighth subcomponent with respect to 100 moles of the main component is 0 to 4 moles (note that 0 mole and 4 moles are excluded, and the value is in terms of an A oxide).

A roofing system is provided comprising a multiplicity of courses of roofing shingles having a reduced-width headlap portion and a non-straight longitudinal front edge, wherein a lateral trailing edge of a shingle in a single course overlaps (side-laps) an adjacent previously installed shingle, and where the buttlap portion includes an exposed buttlap portion having a surface area that is greater than the surface area of the headlap portion.

A dielectric ceramic composition, comprising a main component including barium titanate; a first subcomponent including at least one kind selected from MgO, CaO, BaO and SrO; a second subcomponent functioning as a sintering auxiliary agent; a third subcomponent including at least one kind selected from V2O5, MoO3 and WO3; a fourth subcomponent including an oxide of R1 (note that R1 is at least one kind selected from Sc, Er, Tm Yb and Lu); a fifth subcomponent including CaZrO3 or CaO+ZrO2; and an eighth subcomponent including an oxide of A (note that A is at least one kind selected from a cation element group having an effective ionic radius at the time of 6 coordination of 0.065 nm to 0.085 nm); wherein a ratio of the eighth subcomponent with respect to 100 moles of the main component is 0 to 4 moles (note that 0 mole and 4 moles are excluded, and the value is in terms of an A oxide).