The PCB polishing device for mechanical electronic engineering comprises a box body, a moving plate is arranged in the box body, two electric push rods are arranged between the moving plate and the inner top of the box body, a sliding block which is in sliding connection with the moving plate is arranged in the middle of the moving plate in an up-down penetrating mode, and a polishing machine is installed at the bottom of the sliding block. And a driving mechanism is arranged between the sliding block and the moving plate, driving plates are installed at the bottoms of the two ends of the moving plate, first inclined faces are arranged at the lower ends of the opposite faces of the two driving plates, and four supporting rods are installed at the inner bottom of the box body. By means of work of an electric push rod, the polishing machine can move downwards, meanwhile, two L-shaped plates can be driven to move relatively, a PCB is clamped, the polishing machine moves in a reciprocating mode under transmission of a lead screw, the surface of the PCB can be polished, meanwhile, dust generated during polishing can be sucked into a water tank, and the dust is treated and collected; and the pollution to the workshop environment is reduced.