The invention discloses a U-shaped self-propelled wave power generation device. The wave power generation device comprises a ship body, a wave energy collection and conversion mechanism and a propelling mechanism; the ship body comprises a cabin, a cockpit, a device chamber, a deck and a tail plate, wherein the deck is arranged at the upper part of the cabin, the cockpit is arranged on the deck, the device chamber is arranged inside the cabin, and the tail plate is arranged at the tail part of the cabin; the wave energy collection and conversion mechanism comprises a front vertical pipe, a front air turbine generator set, a rear air turbine generator set, a rear vertical pipe and a horizontal pipe; and the horizontal section of the front vertical pipe is approximately triangular, and the horizontal section of the rear vertical pipe is quadrilateral, the vertical section of the horizontal pipe is pentagonal, and the front vertical pipe, the horizontal pipe and the rear vertical pipe sequentially communicate to form a U-shaped channel. The wave power generation device has the advantages that a foundation is laid for low cost, the wide sea area and high-efficiently utilization of thewave energy.