39results about How to "Reduce local concentration" patented technology

An analyte sensor for use in connection with a biofluid is described. The analyte sensor may comprise any suitable interface between the biofluid and a derivative of the biofluid and any suitable transducer of information concerning an analyte. At least one catalytic agent is provided in a locale or vicinity of the interface. The catalytic agent, such as a proteinaceous agent or a non-proteinaceous, organic-metal agent, is sufficient to catalyze the degradation of reactive oxygen and/or nitrogen species that may be present in the vicinity of the interface. An analyte-sensing kit and a method of sensing an analyte are also described.

Heparinase enzymes can be used as a medical treatment to reduce localized inflammatory responses. Treatment of activated endothelium with heparinase inhibits leukocyte rolling, adhesion and extravasation. Most of the heparin and heparan sulfate on endothelial cell surfaces and in basement membranes is degraded by exposure to heparinase. In addition, immobilized chemokines, which are attached to heparin/heparan sulfate on activated endothelium are solubilized by heparinase digestion. Heparinase can be infused into the vascular system to inhibit accumulation of leukocytes in inflamed tissue and decrease damage resulting from localized inflammations. Targeting of heparinase to activated endothelium can be accomplished through localized administration and/or use of genetically engineered heparinase containing endothelium ligand-binding domains.

The invention discloses a sparking plug ignition-type premixing compression ignition system of an internal combustion engine, and belongs to the technical field of combustion of internal combustion engines. According to the premixing compression ignition system, a high-energy sparking plug is adopted for igniting diesel oil or igniting mixtures of the diesel oil and other fuels, wherein the dieseloil or the mixtures serve as the fuels for premixing and are jetted out in a gas feeding process or a compression process to generate premixing gas in a combustion chamber. By adopting an effective compression ratio under which the premixing gas cannot be ignited, the premixing gas in a cylinder cannot burn spontaneously; by using the high-energy sparking plug for ignition close to a compressionupper limit point, the mixed gas nearby the sparking plug is ignited to make the temperature and the pressure in the cylinder quickly rise, the other remaining premixing gas in the cylinder satisfiesthe conditions for spontaneous combustion, large-scale multi-point spontaneous combustion happens, and fast combustion of the premixing gas is achieved. By adopting a high expansion ratio, the heat efficiency is further improved.

The invention relates to the chemical field of inorganic salt and discloses a method for preparing highly-dispersed magnesium hydroxide by magnesium salt. By adopting a synchronous feeding method and inorganic magnesium salt and inorganic alkaline liquor as raw materials, the pH value is controlled to obtain a magnesium hydroxide mixed liquid; and the magnesium hydroxide liquid is aged, suction-filtered, washed and dried to prepare magnesium hydroxide powder. By using water as a substrate and synchronously adding the inorganic magnesium salt and inorganic alkaline liquor, the local concentration of the reactant can be effectively reduced so as to prevent magnesium hydroxide from forming a colloid. The obtained magnesium hydroxide powder is small in grain size and uniform in size and is highly dispersed. The method disclosed by the invention is simple in synthetic process, mild in reaction condition and convenient for industrial production.

The invention provides an aceclofenac bi-layer osmotic pump controlled release tablet and a preparation method thereof, belongs to the technical field of medicinal preparation. The osmotic pump preparation comprises a tablet core containing aceclofenac and a semipermeable coating membrane which is coated outside the tablet core and provided with orifices, the tablet core comprises a drug layer containing aceclofenac and a boosting layer; wherein, the drug layer comprises the following components: 200mg of aceclofenac, 100mg-300mg of suspension, 10mg-50mg of osmotic stress active substance and0.5 mg-2mg of lubricant; the boosting layer comprises 50mg-150mg of sweller and 5mg-30mg of osmotic stress active substance; the semipermeable coating membrane comprises the following components: 10g-20g of semipermeable high polymer material dissolved in 500ml of acetone and 2g-5g of water soluble pore former dissolved in 20ml of distilled water and the weight of the coating membrane is 5%-10% of the tablet core weight; laser or a power drill is used to drill the orifices on the drug-containing side of the coating tablet. The invention is characterized of less dosing frequency, convenient taking way, long lasting and stable curative effect and can be used to cure pains and inflammations caused by osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and the like.

A negative electrode element for a lithium-ion secondary battery includes: a negative electrode current collector; and a negative electrode layer that includes an alloying active material layer formed on the negative electrode current collector and a resin layer formed on a surface of the alloying active material layer so as to have an opening that exposes part of the alloying active material layer to a surface of the negative electrode layer. The surface of the alloying active material layer, exposed to the opening, and a surface of the resin layer form a step so that the surface of the resin layer is farther from a surface of the negative electrode current collector than the exposed surface of the alloying active material layer.

The invention discloses a mini-pill type nicergoline capsule and a preparation method thereof. The mini-pill type nicergoline capsule is a sustained-release preparation and is prepared from a capsule shell and a nicergoline mini-pill accommodated in the capsule shell, wherein the nicergoline mini-pill sequentially comprises an empty pill core, a main drug layer and a pigmented layer from inside to outside; the main drug layer accounts for 15-60 percent of the empty pill core, and the pigmented layer accounts for 0.5-1 percent of the total weight of the empty pill core and the main drug layer. The mini-pill type nicergoline capsule has the advantages of small stimulation to intestines and stomach, high utilization rate, high stability, less toxic or side effects and capability of fully releasing effective components in time.

The invention provides a dexketoprofen coating sustained-release micro-encapsulated capsule and a preparation method thereof, which belong to the technical filed of chemico-pharmaceutical preparations. The coating sustained-release micro-encapsulated capsule consists of coating sustained-release particles and a capsule shell. The coating sustained-release particles are made of core particles containing dexketoprofen basic remedy through a coating technique. The invention can reduce the stimulation of the dexketoprofen on gastrointestinal tract and taking times, consequently, the medication compliance of patients is improved, the fluctuation of dexketoprofen blood concentration is reduced, bioavailability and treatment effect are improved and adverse reactions are reduced.

The invention relates to a potassium ion battery amide electrolyte with high stability. The electrolyte comprises an amide solvent, an electrolyte and an additive, the concentration of the electrolyte is 5-14 mol L <-1 >, and the content of the additive accounts for 0-16% of the total volume of the electrolyte. The potassium ion battery amide electrolyte with high stability is used in a potassium ion battery; the electrolyte provided by the invention can buffer the volume fluctuation of graphite in the charging and discharging process, and effectively inhibit the side reaction of the electrolyte and the graphite so as to improve the electrochemical stability of the graphite; and after the additive HFE is added into the SEI film, the content of KF can be further increased to stabilize the interface between the electrode and the electrolyte, the local concentration of the electrolyte can be reduced, and the diffusion rate of ions in the battery is improved.

The invention belongs to the technical field of pharmaceutic preparations, and discloses a flurbiprofen double-layer osmotic pump controlled-release tablet and a preparation method thereof. The flurbiprofen double-layer osmotic pump controlled-release tablet comprises flurbiprofen and a pharmaceutically acceptable polymer, and consists of a tablet core and a controlled-release coat coating the tablet core and having medicine-releasing holes, wherein a medicine layer comprises 200mg of flurbiprofen, 10-90mg of osmotic active substance, 100-300mg of suspension and 3-10mg of lubricant; a boosting layer comprises 100-200mg of sweller and 10-50mg of osmotic active substance; a semipermeable coat comprises 10-20g of semipermeable high molecular material, 0.5-3g of water-soluble pore-foaming agent and a proper amount of an organic solvent; the weight of the coat is 6-12% that of the tablet core; 1-2 medicine-releasing holes are drilled in one side of the medicine layer of the coated tablet by using laser or a mechanical drill. The flurbiprofen double-layer osmotic pump controlled-release tablet can effectively adjust constant-speed medicine release to obtain steady blood concentration, thereby reducing the medicine taking times and improving patient compliance, and has the characteristics of few medicine taking times, convenience in taking, lasting effect and stable therapeutic effect.

The invention relates to a condensation and reheating integration type smoke plume white-eliminating system. The system comprises a denitration device, a flue gas waste heat utilization device, an electrostatic precipitator, a wet desulphurization device, an induced draft fan, a tail flue gas heater and a chimney which are connected in series in order, wherein the flue gas waste heat utilization device is used for recovering flue gas waste heat, and the tail flue gas heater is used for raising flue gas temperature. Compared with the prior art, the system utilizes the flue gas waste heat to heat condensed water, recovers the flue gas waste heat, and reduces the salt content; the tail flue gas heater utilizes a steam turbine to extract air so as to heat flue gas and raise the flue gas temperature; at the moment, the salt content of the steam of flue gas is not high, the steam temperature is raised, and the density declines; and thus, the flue gas is beneficially diffused to higher heightafter being discharged into the atmosphere, the local concentration of the flue gas discharged into the atmosphere is reduced, and the impact of flue gas containing smoke on the environment is reduced.

There is provided a water purification catalyst element (100). The catalyst element (100) comprises a porous support (102) having a first surface (106) and a second surface (110). The first or the second surface (106, 110) delimit a conduit (114) through the catalyst element (100). A material (104) comprising a noble metal is supported on the porous support (102). At least the first surface (106) is coated with a coating material (108) permeable to hydrogen gas and impermeable to water, and at least the second surface (110) is water-permeable. This catalyst element (100) can selectively convert nitrites and/or nitrates to N₂ gas and can be used to provide a cost efficient and/or maintenance free water purification setup. There is also provided a water purifier (200) comprising the catalyst element (100), a beverage maker (300) comprising the water purifier (200), a method (1800) of water purification and a method (1900) of making the catalyst element (100).