The invention discloses a machine manufacturing drilling machine with a fixed base; bolt holes are fixedly formed in the four corners of the upper end face of the fixed base. The upper end face of thefixed base is fixedly connected with a supporting column. A workpiece fixing device is fixedly connected to the middle of the side end face of the supporting column. The workpiece fixing device comprises a movable fixing plate, a threaded hole, a limiting column, a connecting column, a threaded clamping groove, a threaded column, a fixed clamping groove, piston clamping grooves, a fixed main bodyand a movable groove; the movable groove is formed in the upper end surface of the fixed main body; the movable fixing plate is slidably connected to the interior of the movable groove through the connecting column; the threaded hole is formed in the upper end face of the movable fixing plate, the limiting column is slidably connected to the upper end face of the movable fixing plate, the fixed clamping groove is formed in the side, away from the movable groove, of the upper end face of the fixed main body, and the piston clamping grooves are formed in the two sides of the interior of the fixed clamping groove. The drilling machine can provide good fixing performance for the workpiece, and meanwhile the safety performance of the device is greatly improved.