The invention discloses a method for culturing pearls. The method is characterized in that within a certain culturing time, the pearl mussel culturing density is reduced correspondingly with the extension of the culturing time, that is, 2000 pearl mussels are cultured per mu in the first year, 1500 pearl mussels are cultured per mu in the second year, 1000 pearl mussels are cultured per mu in the third year, and 500 pearl mussels are cultured per mu in the fourth year and later. Hyriopsis cumingii is cultured with a mesh bag hanging method, five pieces of the hyriopsis cumingii are cultured per bag in the first year, four pieces of the hyriopsis cumingii are cultured per bag in the second year, three pieces of the hyriopsis cumingii are cultured per bag in the third year, and two pieces of the hyriopsis cumingii are cultured per bag in the fourth year and later. According to the culturing method, on one hand, the culturing water surface can be used reasonably according to sizes of the pearl mussels, on the other hand, the pearl mussels are cultured in a relatively suitable water body all the time, and a good water body environment is created for the pearl mussels, so that growth of the pearl mussels and protection of the ecological environment are facilitated, and the pearl culturing benefit is increased.