The invention relates to a safe 3D printing device with a platform cleaning function, comprising an operation box, a cleaning box, a working box, a screen, a power device and a cleaning mechanism, a driving mechanism is arranged in the cleaning box, and an ash collection box is arranged in the operation box , the cleaning mechanism includes a motor, a screw, a nut, a moving plate, a liquid storage tank, a liquid inlet pipe and a liquid discharge pipe, the driving mechanism includes a compression pipe, a filter unit and a moving unit, and the filter unit includes a filter pipe, an air inlet pipe and an exhaust pipe , the safe 3D printing equipment with platform cleaning function can remove the dust or raw material particles attached to the support platform through the cleaning mechanism, so as to avoid excessive accumulation of dust or raw material particles and cause warping at the bottom of the product. Not only that, through The driving mechanism, the 3D printer can filter out the toxic ultrafine particles released during operation, and prevent the excessive accumulation of toxic ultrafine particles from causing lung diseases and blood system diseases.