47 results about "Late phase" patented technology

The invention relates to a method for differentially representing myocardial tissue in different states of damage, comprising the following steps: administering a myocardium-suitable contrast agent to a patient under examination; entering at least one patient-specific parameter affecting the speed of uptake by and elimination from the myocardium of said contrast agent; calculating a point in time after administration of the contrast agent at which a difference between a contrast agent content in necrotic myocardial tissue and a contrast agent content in non-necrotic myocardial tissue attains a maximum value, on the basis of the at least one patient-specific parameter, and carrying out, at the point in time calculated, a late-phase CT scan for accentuation of necrotic myocardial tissue compared to non-necrotic myocardial tissue. The invention likewise relates to apparatus, in particular for carrying out the method. A clean copy of the abstract that incorporates the above amendments is provided herewith on a separate page.

An inter-symbol interference (ISI) pattern-weighted early-late phase detector is provided. I and Q clocks are generated. The I clock frequency is divided by n, creating a reference clock. A serial data stream is sequentially sampled with the I clock, and with Q clocks having fixed and varied phase delays from the I clock, creating digital I-bit and Q-bit values. The I-bit values and Q-bit values are segmented into n-bit digital words. I clock phase corrections are identified and a modulation factor is determined in response to comparing Q-bit values sampled by the varied delay Q clock. Also identified are bit sequence patterns associated with each I-bit value. Each I-bit value is weighted in response to the identified bit sequence pattern and the identified I clock phase correction. The modulation factor is applied to the weighted average, and I and Q clock phase error signal are generated.

The invention concerns bifunctional fusion molecules for the treatment of IgE-mediated allergic conditions and FcepsiRI-mediated autoimmune conditions. The invention provides a new therapeutic approach for the treatment of both acute and late-phase allergic responses due to ingestion, inhalation, cutaneous and parenteral exposure to allergens, responses including asthma, allergic rhinitis, atopic dermatitis, severe food allergies, chronic urticaria and angioedema, as well as anaphylactic reactions due to exposures such as bee stings or penicillin allergy. In addition, the invention provides for a novel, safer and more efficacious form of allergy vaccination.

The invention concerns bifunctional fusion molecules for the treatment of IgE-mediated allergic conditions and FcεRI-mediated autoimmune conditions. The invention provides a new therapeutic approach for the treatment of both acute and late-phase allergic responses due to ingestion, inhalation, cutaneous and parenteral exposure to allergens, responses including asthma, allergic rhinitis, atopic dermatitis, severe food allergies, chronic urticaria and angioedema, as well as anaphylactic reactions due to exposures such as bee stings or penicillin allergy. In addition, the invention provides for a novel, safer and more efficacious form of allergy vaccination.

The present invention is an ophthalmic composition containing a relatively high concentration of olopatadine. The composition is typically an ophthalmic aqueous solution containing relatively high concentrations of olopatadine solubilized within the solution. The composition is preferably capable of providing enhanced relief from symptoms of ocular allergic conjunctivitis, particularly late phase symptoms of ocular allergic conjunctivitis.

The present invention is an ophthalmic composition containing a relatively high concentration of olopatadine. The composition is typically an ophthalmic aqueous solution containing relatively high concentrations of olopatadine solubilized within the solution. The composition is preferably capable of providing enhanced relief from symptoms of ocular allergic conjunctivitis, particularly late phase symptoms of ocular allergic conjunctivitis.

A method for promoting wound healing and preventing scar formation in a variety of wounds in skin, mucosa, and cornea. The method comprises administering a therapeutically effective amount of a histone deacetylase inhibitor or a hyperacetylating agent. The histone deacetylase inhibitor or hyperacetylating agent is capable of stimulating multiple cytokines / growth factors in the early phase of wound healing, and suppressing fibrogenic cytokines / growth factors in the late phase of tissue remodeling in the wound site, and is useful in promoting epithelial cell re-growth and reducing excessive collagen accumulation, which results in rapid wound closure with reduced scaring.

The invention provides an ultrasound diagnosis apparatus, an image processing apparatus, an image processing method, and an image display method. When an image creating unit creates a three-dimensional ultrasound image of a blood-vessel early phase, an operator presses an image selecting button, and selects an area to be displayed as superimposed by using an image-selecting Graphical User Interface (GUI) displayed by an image-selecting GUI display-control unit. After the image creating unit start creation of a three-dimensional ultrasound image in a late phase, when the operator presses a composition display button, the movement-distance calculating unit calculates a movement distance between a three-dimensional tissue image at the moment of the press of the composition display button and each of three-dimensional tissue images in the area to be displayed as superimposed, and an image correcting unit corrects each of three-dimensional contrast enhanced images corresponding the three-dimensional tissue images of the blood-vessel early phase by using the movement distance. An animated-image compositing unit creates a group of images for animation that the corrected three-dimensional contrast enhanced images of the blood-vessel early phase are each combined with a three-dimensional contrast enhanced image of the late phase, and a monitor displays the group of the images for animation in animation.

The invention discloses a one-step seedling culture method of wheat anther, which comprises the following steps of: selecting young spike of wheat with wheat pollen cells developing to mononuclear metaphase to late phase, and pretreating for 2 days at low temperature (2-4 DEG C); after conventional disinfection, stripping anther tissue from the pretreated young spike of wheat, and inoculating the anther tissue on one-step seedling culture medium for shade culture; and when growing visible callus, placing the cultured anther tissue under 1500Lx lighting conditions and culturing for a week, and then increasing the light intensity to 3000Lx-4000Lx and continuously culturing for two weeks to produce pollen plants with vigorous roots and seedlings. The method omits two necessary technical operation links of induction of adventitious buds and induction of adventitious roots by the pollen callus, the culture cost is reduced by nearly 50%, the culture days are shortened by 40-50 days, the average induction rate of green seedlings is equivalent to that of multistep seedling, the albino seedling rate is generally reduced by 10 percent, and test-tube seedlings are vigorous and has developed root system, connecting parts of rootstalks have little or no callus tissue residues, and the transplantation survival rate of the test-tube seedlings is high.

The invention provides a Chinese medicinal capsule for treating late phase liver cancer, wherein the recipe includes Bupleurum root, zedoary, pinellia tuber, dried orange peel, amomum fruit each 12g, Hypericum japonicum Thunb. , raw astragalus root, oldenlandia, dandehon herb each 30g, pilose asiabell root, poria cocos wolf each 20g, white atractylodes rhizome, fructus akebiae each 15g, centipede 2 pieces, haw, medicated leaven, malt each 10g, licorice root 6g, artemisia capillaris thumb, red phaseolus bean each 30g, rhubarb horsetails 6g, poria peel, polyporus umbellatus, oriental water plantain rhizome, waxgourd peel each 30g, notoginseng powder 3g, bletilla tuber 12g, garden burnet root 15g. The Chinese medicament has simplified recipe, easy preparing process and low price.

An inter-symbol interference (ISI) pattern-weighted early-late phase detector is provided. An I clock and a function-controlled oscillation cycle phase delay Q clock are generated. The I clock frequency is divided by n, creating a reference clock. A serial data stream is sequentially sampled with the I clock, and with the function-controlled varied phase delay Q clock, creating digital I-bit and varied phase delay Q-bit values, respectively. The values are segmented into n-bit digital words. I clock phase corrections are identified and a modulation factor is determined in response to comparing varied phase delay Q-bit values with I-bit values. Also identified are bit sequence patterns associated with each I-bit value. Each I-bit value is weighted in response to the identified bit sequence pattern and the identified I clock phase correction. The modulation factor is applied to the weighted average, and I and Q clock phase error signals are generated.

The invention discloses a method for realizing microprocessor-based automatic quasi-synchronization function, which comprises the following steps: 1) accurately measuring the phase-angle difference of two sides of a breaker at intervals of T0 by a microprocessor-based automatic quasi-synchronization device, and taking the latest phase-angle difference deltai of n points; 2) establishing a quadratic or frequentative polynomial mathematical model of time coordinates for the phase-angle difference of voltages on the two sides of the breaker; 3) according to a phase-angle difference sequence delta, carrying out best square approach on parameters of the mathematical model; and 4) substituting lead time tDL of closing of the breaker into the mathematical model, calculating the closing of the device in the current point, sending a closing pulse if the calculated phase-angle difference of the two sides of the breaker after the tDL is close to zero and does not violate other synchronous closing and locking conditions, and continuing capturing synchronous points if the calculated absolute value of the phase-angle difference is larger than an allowable closing phase angle. The method establishes precise mathematical model by utilizing the change law of the phase-angle difference of the voltages on both sides of the breaker, reduces the influence of the measuring errors on the synchronous closing according to the model, and realizes the accurate prediction for synchronous closing points.

The invention discloses a nuisance free wheat insecticide with biological source which is prepared mainly from ethylicin, sophocarpidine, compound sodium nitrophenolate, cyhalothrin through watering, mixing uniformly to prepare aqueous emulsion. The insecticide is mainly used for the prevention and cure of damage by disease and insect for late phase wheat.

The invention belongs to the artificial slab manufacturing field, and mainly solves the problems of saving energy and water in the cold-hot-cold gluing process. An energy and water saving device of the cold-hot-cold gluing process is as follows: a hot-water circulatory tank, a warm-water circulatory tank and a cold-water circulatory pool are arranged at the side of a multilayer thermal press and form three independent circulatory system device of hot-water, warm-water and cold-water through pipelines and valves, respectively. An energy and water saving method of the cold-hot-cold gluing process is as follows: in the first phase, the middle phase and the late phase of the pressure keeping and cooling stage, the hot-water circulatory tank, the warm-water circulatory tank and the cold-water are respectively utilized to cool each hot pressboard of the multilayer thermal press and the blank of each hot pressboard at the temperatures of about 145 DEG C, about 100 DEG C and about 60 DEG C in sequence in the three steps; the temperatures are reduced to about 100 DEG C, about 60 DEG C and about 30 DEG C in sequence; and high temperature water, intermediate temperature water and low temperature water produced in sequence are recycled in three steps, thus achieving the purposes of saving energy and water.

A nasal solution and method for treating nasal and sinus inflammation. The nasal solution includes vitamin C, an extract of scutellaria radix, an extract of eleutherococcus radix, an extract of chamomile, and a pharmaceutically acceptable carrier which is suitable for administering the vitamin C, the scutellaria radix extract; the eleutherococcus radix extract; and the chamomile to the nose of a patient. The method includes administering the nasal solution which suppresses early phase and late phase mediators of allergic mucosal disease in order to maintain long-term inhibition of nasal and sinus inflammation.

The invention discloses a propolis wine with heydyotis and its preparation method; the invention provides the propolis wine prepared by a combination of propolis and heydyotis, as well as its preparation method. The technical schemes are: the formula composition comprises propolis, heydyotis and wine, wine is one type selected from matrix wines of alcohol, liquor, yellow rice wine, rice wine or fruit wine, heydyotis selects an original medicinal material whole plant; the formula composition comprises the following ingredients by weight: 5 to 20 of propolis, 5 to 20 of heydyotis and 50 to 200 of wine; the preparation method comprises the following steps: grinding or ultramicro grinding propolis for preparing powder, decocting heydyotis into paste or preparing powder, placing into a container; immersing for 7 - 30 days by adding wine, shaking for 1 - 3 times every day, wherein 3 - 10 minutes each time; standing for 1 - 7 days and filtering, and then obtaining. The invention is suitable for an auxiliary health caring of tumor patients of an early phase, a middle phase and a late phase, and the patients with tonsillitis, pharyngolaryngitis, urinary tract infection, pelvic inflammation, appendicitis and hepatitis.

The invention discloses a DNA probe pool for detecting kawasaki disease related gene and SNP locus, as well as preparation method and application thereof. The DNA probe pool comprises 558 oligonucleotide probe sequences which are shown by SEQ ID NO:3-SEQ ID NO:560. Each oligonucleotide probe sequence comprises a 21bp universal sequence at the 5' end, a 120bp sequence which can be specifically bonded with gene, and a 21bp universal sequence at the 3' end; the 21bp universal sequence at the 5' end and the 21bp universal sequence at the 3' end of the oligonucleotide probe sequence are shown by SEQ ID NO:1-SEQ ID NO:2 respectively. According to the detection method disclosed by the invention, the detection cost can be reduced, the detection precision can be improved, and an in-vitro qualitative detection means can be provided for the kawasaki disease pathogenesis, prognosis and medicinal cure effect, as well as an effective auxiliary diagnosis way can be provided for reducing coronary artery lesion and other heart diseases triggered in the late phase of kawasaki disease.

A method for promoting wound healing and preventing scar formation in a variety of wounds in skin, mucosa, and cornea. The method comprises administering a therapeutically effective amount of a histone deacetylase inhibitor or a hyperacetylating agent. The histone deacetylase inhibitor or hyperacetylating agent is capable of stimulating multiple cytokines / growth factors in the early phase of wound healing, and suppressing fibrogenic cytokines / growth factors in the late phase of tissue remodeling in the wound site, and is useful in promoting epithelial cell re-growth and reducing excessive collagen accumulation, which results in rapid wound closure with reduced scaring.

An inter-symbol interference (ISI) pattern-weighted early-late phase detector is provided. I and Q clocks are generated, where the Q clock has a fixed phase delay with respect to the I clock. The I clock frequency is divided by n, creating a reference clock. A serial data stream is sequentially sampled with the I and Q clocks, creating digital I-bit and Q-bit values, respectively. The I-bit values and Q-bit values are segmented into n-bit digital words. In response to analyzing the I-bit and Q-bit values, I clock phase corrections are identified. Also identified are bit sequence patterns associated with each I-bit value. Each I-bit value is weighted in response to the identified bit sequence pattern and the identified I clock phase correction. A phase error signal is generated by averaging the weighted I-bit values for each n-bit digital word, and I clock is modified in phase.

An inter-symbol interference (ISI) pattern-weighted early-late phase detector is provided. I and Q clocks are generated. The I clock frequency is divided by n, creating a reference clock. A serial data stream is sequentially sampled with the I clock, and with Q clocks having fixed and varied phase delays from the I clock, creating digital I-bit and Q-bit values. The I-bit values and Q-bit values are segmented into n-bit digital words. I clock phase corrections are identified and a modulation factor is determined in response to comparing Q-bit values sampled by the varied delay Q clock. Also identified are bit sequence patterns associated with each I-bit value. Each I-bit value is weighted in response to the identified bit sequence pattern and the identified I clock phase correction. The modulation factor is applied to the weighted average, and I and Q clock phase error signal are generated.

The invention discloses a method for producing furfural by the aid of pre-hydrolysis liquid of eucalyptus. The method includes steps of (1), washing eucalyptus chips, then steaming the eucalyptus chips by the aid of steam, squeezing, grinding and tearing the eucalyptus chips by the aid of double-screw squeezing fluffers, arranging the ground eucalyptus chips in cooking vessels, adding water into the cooking vessels and carrying out hydrolysis on the eucalyptus chips to obtain the pre-hydrolysis liquid of the eucalyptus; (2), carrying out reaction on the pre-hydrolysis liquid of the eucalyptus and sulfuric acid to obtain the furfural. The pentose extraction rate can reach the maximum value of 57.51% under preferable conditions, and the furfural yield can reach the maximum value of 71.89% under the technical conditions that the temperature is 180 DEG C, the concentration of H2SO4 is 0.25%, the gas extraction speed is 15 mL / min and the concentration of xylose is 17.8 g / L. The method has the advantages that the pre-hydrolysis liquid of the eucalyptus is reasonably utilized for preparing the furfural, the eucalyptus is subjected to screw squeezing and grinding pre-treatment, and accordingly the utilization rate of the eucalyptus in late-phase reaction can be increased; preparation processes are adjusted, so that the pre-hydrolysis liquid does not contain fiber polysaccharides such as cellobiose and cellotriose, pyrogenic reaction can be reduced, and the furfural yield can be effectively increased.

The invention belongs to the field of medicines and in particular relates to a method for preparing a novel animal model of asthma. The method for preparing the novel animal model of asthma disclosed by the invention is easy to operate, and anesthesia is not needed. The animal model of asthma obtained by adopting the preparation method disclosed by the invention is high in animal reactivity, is suitable for researching the whole asthmatic attack reaction process comprising immediate-phase reaction and late-phase reaction of asthma, and can be used for screening and finding novel medicines for treating the asthma and other researches.

A nasal solution and method for treating nasal and sinus inflammation. The nasal solution includes vitamin C, an extract of scutellaria radix, an extract of eleutherococcus radix, an extract of chamomile, and a pharmaceutically acceptable carrier which is suitable for administering the vitamin C, the scutellaria radix extract; the eleutherococcus radix extract; and the chamomile to the nose of a patient. The method includes administering the nasal solution which suppresses early phase and late phase mediators of allergic mucosal disease in order to maintain long-term inhibition of nasal and sinus inflammation.

This invention provides a dermatological preparation to improve skin cosmesis or conditioning by using different formulations in a sequence that suits the needs of the skin at different points of the hormonal cycle. In its simplest implementation, this would be a two-phase skin treatment, such as a cosmetic, lotion or soap whose formulation changes to balance the differing states of hydration and reactivity of the skin during the early and late phases of the cycle. The formulations would be made in a way to be easily identified and delivered conveniently for use at different times of a hormonal cycle. The preparation would be packaged to permit the convenient purchase and dispensing of the different formulations in a manner that could be easily sequenced with the hormonal cycle.

A feeding regime for increasing the incorporation efficiency of omega-3 HUFAs in poultry meat is provided. Specifically, the poultry is fed a higher amount of omega-3 HUFAs in the late phase of poultry's production period than in the early phase.

An inter-symbol interference (ISI) pattern-weighted early-late phase detector is provided. I and Q clocks are generated, where the Q clock has a fixed phase delay with respect to the I clock. The I clock frequency is divided by n, creating a reference clock. A serial data stream is sequentially sampled with the I and Q clocks, creating digital I-bit and Q-bit values, respectively. The I-bit values and Q-bit values are segmented into n-bit digital words. In response to analyzing the I-bit and Q-bit values, I clock phase corrections are identified. Also identified are bit sequence patterns associated with each I-bit value. Each I-bit value is weighted in response to the identified bit sequence pattern and the identified I clock phase correction. A phase error signal is generated by averaging the weighted I-bit values for each n-bit digital word, and I clock is modified in phase.

There is provided an ex-vivo insect screening model to accurately determine blood-brain barrier penetration of different nanoparticles in order to improve the compound screening procedures / processes in the early drug discovery process. This object offers many advantages relative to prior technologies since insect models are more reliable tools for the decision-making process than the existing in vitro models, and will speed up the drug screening process and reduce the late phase attrition rate. Moreover, it will reduce the number of mammals sacrificed during the drug discovery phase.

The invention provides a large-scale seedling method for Cape jasmine seeds. The method comprises the steps of nursery garden selection, seeding time, seed treatment, shed building and compartment preparation, seeding density, management before sprouting, prophase management after sprouting, mid- and late-phase management after sprouting and seedling transplantation. According to the method provided by the invention, nursery garden selection requirements in culture of Cape jasmine seedlings are standardized, nursery garden selection and utilization and soil treatment are performed according to stipulation of the invention, and thus an infection rate of the seedlings is extremely low, and a survival rate of the seedlings after transplantation is more than 97%. The seedlings are robust, with bottle green leaves, multiple, thick and white root systems, and strong stems, the diameter of the seedlings is more than 0.4cm, and the seedlings grow vigorously.

A method for examining a complement system of a subject, including: a reaction step of letting a scavenger receptor or a functional equivalent thereof, a pentraxin family protein or a functional equivalent thereof and a blood sample collected from the subject coexist in vitro; and a detection step of detecting complement activation amplifying reaction and / or complement activation late-phase reaction induced by interaction between the scavenger receptor or the functional equivalent thereof and the pentraxin family protein or the functional equivalent thereof from a reactant after the reaction step. Also provided are a kit for examining a complement system, and a method for testing a test substance for the ability to activate or suppress a complement system.