The invention discloses a preparation method for a highly water-pressure-resistant, highly air permeable and highly wet permeable garment film. The preparation method comprises the following steps of: mixing dispersed polytetrafluoroethylene resin powder with a solvent and a surfactant in a certain mass ratio; and performing maturing, blank-making, extrusion molding, calendering, one-time drawing, desolventizing, intermediate-temperature secondary longitudinal drawing, low-temperature secondary transverse drawing, high-temperature thermal treatment and sizing and the like. The method is simple in batch production process, and controllable and environmental-friendly in production process, quality is stable and appearance is good. The film has the characteristics of being highly water-pressure-resistant, great in air and wet permeability, washable, stable in chemical property and the like. The film is particularly suitable for the field of outdoor waterproofness, air permeable and wet permeable garments, shoes, military uniforms and the like.