The invention relates to the field of
titanium and
titanium alloy processing, in particular to a photoetching micro-patterning mechanically-stable TNTs film and application thereof, and a preparation method of the photoetching micro-patterning mechanically-stable TNTs film comprises the following steps: (1) carrying out alkali heat treatment on the surface of a
titanium-based material; (2) spin-
coating photoresist on the surface of the titanium-based material subjected to alkali heat treatment; (3) covering the
photoresist by using a
mask, and exposing by using
ultraviolet light; (4) soaking the exposed titanium-based material in a developing solution; (5) the titanium-based material obtained in the step (4) is soaked in
etching liquid, and then ultrasonic cleaning and baking are conducted; (6) carrying out
anodic oxidation on the etched region; (7) the
photoresist is removed, and a mechanically stable TNTs thin film subjected to photoetching micro-patterning is obtained; the
surface structure of the mechanically stable TNTs thin film subjected to photoetching micro-patterning is that TNTs are embedded in a groove formed by
etching. Different pattern masks are manufactured through photoetching and wet
etching technologies, square, hexagonal and circular (S / H / R) micro-patterns TNTs are formed, and higher stripping resistance and
wear resistance are shown; in addition, the micro-pattern TNTs reserve a
nanotube structure, so that the growth and differentiation of osteoblasts are facilitated; the micro-pattern TNTs show optimal
coating mechanical stability, cytocompatibility and osteogenesis performance in an experimental group, and become an ideal platform for developing a multifunctional
implant.