19 results about "Nasal Turbinate" patented technology

The invention provides a formula for treating rhinitis, and belongs to the technical field of traditional Chinese medicine, the formula for treating rhinitis is prepared from centipeda minima, schizonepeta spike, magnolia flower, cocklebur fruit, radix angelicae, rhizoma atractylodis, rhizoma acori graminei, cavalerie mosla herb, asarum, sal ammoniac, dried alum, musk, borneol and 50-degree white spirit according to specific parts by weight, and the preparation method comprises the following steps: firstly, removing impurities from part of the raw materials, and crushing into powder; when the traditional Chinese medicine is used, the liquid medicine is used for cleaning the nasal cavity and is repeated for 3-5 times, the formula has a good curative effect on diseases such as acute and chronic rhinitis, turbinate hypertrophy, nasal polyp, nasosinusitis and the like, clinical embodiments prove that the symptoms of a chronic rhinitis patient basically disappear after the chronic rhinitis patient is treated for 4 weeks, and the traditional Chinese medicine has a good curative effect. After a patient with nasosinusitis is treated for 6 weeks, inflammation is obviously absorbed, and after a patient with hypertrophy of nasal turbinates is treated for 8 weeks, ventilation basically returns to normal.

A catheter assembly (1) for use in septoturbinatoplasty procedures. The catheter has a shaft (20) and a primary balloon (10) which comprises a base (B) for positioning against the nasal floor, a roof (R) opposed from the base (B) and a side surface (SS) extending therebetween for bearing against a nasal septum and / or an inferior turbinate. The base (B) has a width greater than the roof (R) in a direction transverse to the axis of the shaft (20). The balloon (10) can be inserted into a patients nasal cavity and inflated to realign the patient's septum and / or treat the turbinate.

The invention belongs to the technical field of medical experimental animal models, and discloses a small animal model for skull base high-flow cerebrospinal fluid leakage and skull base reconstruction as well as a construction method and application of the small animal model. The technical obstacle that due to the fact that the nasal cavity of a small animal is narrow and the turbinate structure is complex, surgical instruments cannot reach the skull base through the nose is overcome, meanwhile, a modeling and repairing area is arranged on the rear nasal meatus and the top wall of the nasopharynx, and the temperature and humidity conditions and environment of the nasal mucosa are reserved; and the microenvironment for tissue healing after the endoscopic transnasal skull base surgery is restored on the pathophysiological level. The dissected marking points are clear, and compared with narrow anterior skull base low-flow cerebrospinal fluid leakage of small animals, the standardized bone defect constructed in the middle skull base butterfly saddle area can cause continuous and high-flow cerebrospinal fluid leakage; autologous bone flap and free mucous membrane repair is used, the method is the same as current clinical practice, and a new platform can be provided for screening of skull base repair materials or operation evaluation and retrograde intracranial infection research after an operation.

Described herein are devices, systems, and methods for applying a tension force to various tissues. The devices may be delivered in a minimally invasive fashion and used to manipulate tissues in the nose (e.g., nasal septum, nasal turbinates), ear, and throat. Force may be maintained by the devices for a time period that allows shaping, compression, and / or approximation of tissues.

Endoscopic surgery targeted at the sinuses and nasal turbinates assists in managing the symptoms of chronic rhinosinusitis and other conditions. With contemporary techniques, post-operative hemorrhage, synechiae formation and poor wound healing are amongst the most common complications. The present disclosure provides the use of self-assembling peptide matrix, PuraSinus, and significantly reduces the incidence of these post-operative complications, including prevention of synechiae formation and aiding hemostasis.

A method for intranasal delivery of a formulation comprising Botulinum toxin for the treatment of allergic rhinitis involved impregnating an absorbent tip of an applicator with the formulation, the applicator having a rigid rod having the absorbent tip at a distal end thereof, and inserting the applicator straight into a nasal cavity of a patient beneath the lower turbinates to target the nasal- or nasopharynx-associated lymphoid tissue (NALT) and the eustachian tube opening zone of the nasopharynx within the nasal cavity with the absorbent tip.

The present invention discloses a wearable device for treating eye diseases. The nasal root and trochlear nerve stimulation unit is an electric pulse generating device that outputs an electric stimulation signal. The ethmoid sinus and turbinate heat auxiliary unit overlaps or partially overlaps with the nasal root and trochlear nerve stimulation unit, and includes a heat-conducting component. The vibration unit outputs vibrations of a preset frequency and amplitude. The bending hinge unit is adapted according to the width and curvature of the user's nose. The power manager in the power management unit manages the charging and discharging of the rechargeable battery and the energy recovery. The wireless signal transmission unit is distributed on the periphery of the bending hinge unit, receives program-controlled parameters, and can receive remote commands, including opening or closing, parameter control, mode configuration, program air upgrade, and power acquisition. The present invention uses wearable surface electrical stimulation technology to apply electric pulses to the nerves at the nasal root and trochlear nerves to relieve pain in the back of the eyeball, blurred vision, and symptoms of dry eyes due to dehydration.

The present invention relates to a pharmaceutical composition for preventing or treating Alzheimer's disease, the composition comprising, as an active ingredient, neural crest-derived nasal turbinate stem cells (NTSCs) expressing SSEA3 and CD105. Treatment with the NTSCs expressing SSEA3 and CD105 or with an NTSC cell line including at least a predetermined proportion of the NTSCs was found to result in remarkably good therapeutic activity against Alzheimer's disease. Therefore, the present invention is expected to be effectively used not only as a composition for preventing or treating Alzheimer's disease in which the composition includes, as an active ingredient, NTSCs expressing SSEA3 and CD105 or an NTSC cell line including at least a predetermined proportion of the NTSCs, but also for uses such as screening of NTSC formulations that can be used to treat Alzheimer's disease, or prediction of the therapeutic efficacy thereof.

The present invention relates to the field of medical devices, specifically a maxillary sinus natural opening exploration and expansion kit. Currently, nasal endoscopic surgery is used to treat sinusitis and other diseases, and the uncinate process is usually removed to achieve the patency of the maxillary sinus natural opening, which has many impacts on the patient's postoperative recovery, nasal cavity and sinus function, etc. The technical solution of the present invention includes a probe and expander and an aspirator combination of a curved rod and a curved tube structure. The structural design conforms to the overall spatial structure of the human nasal cavity, maxillary sinus, and sinus orifice and nasal meatus complex. For most patients in clinical practice, this device can avoid the interference of nasal cavity structures such as the front end of the middle turbinate on the treatment operation, and achieve the exploration and expansion of the maxillary sinus natural opening while retaining the uncinate process, and use the aspirator to flush and administer medicine to the maxillary sinus cavity. The patient does not need to be hospitalized for surgery, which avoids the impact of surgical treatment on the patient's future life, greatly reduces the pain and damage during the treatment process, and alleviates the economic and psychological burden of the patient, which is in line with the concept of minimally invasive surgery.

Described herein are devices, systems, and methods for applying a tension force to various tissues. The devices may be delivered in a minimally invasive fashion and used to manipulate tissues in the nose (e.g., nasal septum, nasal turbinates), ear, and throat. Force may be maintained by the devices for a time period that allows shaping, compression, and / or approximation of tissues.

Apparatus and methods for treating conditions such as rhinitis are disclosed herein where a distal end of a probe shaft is introduced through the nasal cavity where the distal end has an end effector with a first configuration having a low-profile which is shaped to manipulate tissue within the nasal cavity. The distal end may be positioned into proximity of a tissue region having a post nasal nerve associated with a middle or inferior nasal turbinate. Once suitably positioned, the distal end may be reconfigured from the first configuration to a second configuration which is shaped to contact and follow the tissue region and the post nasal nerve may then be ablated via the distal end. Ablation may be performed using various mechanisms, such as cryotherapy, and optionally under direct visualization.

Devices for intranasal administration of naloxone are disclosed. The devices comprise a foam applicator and are configured to locate an applicator comprising a naloxone composition. in proximity to the middle turbinate and / or inferior turbinate. Naloxone can be delivered to the nasal mucosa by squeezing the nostril against the applicator. The device and methods of using the devices can be used to treat an opioid overdose.

A nasal turbinate hemostatic electrode includes a main body, where an end of the main body is fixedly connected to a tip; the tip includes a first electrode and a second electrode; side walls of the first electrode and the second electrode are rounded; the first electrode and the second electrode are spaced apart, and have a same surface area; an end of the main body adjacent to the tip is provided with an outlet hole; the outlet hole is connected to an inlet pipe; the outlet hole is configured to deliver an electrolyte to the tip; and the first electrode and the second electrode are configured to conduct a plasma current in the electrolyte. The nasal turbinate hemostatic electrode prevents the surgical electrode from causing a secondary injury to the patient during an operation process, further improving the use safety of the surgical electrode.

A nasal turbinate hemostatic electrode includes a main body, where an end of the main body is fixedly connected to a tip; the tip includes a first electrode and a second electrode; side walls of the first electrode and the second electrode are rounded; the first electrode and the second electrode are spaced apart, and have a same surface area; an end of the main body adjacent to the tip is provided with an outlet hole; the outlet hole is connected to an inlet pipe; the outlet hole is configured to deliver an electrolyte to the tip; and the first electrode and the second electrode are configured to conduct a plasma current in the electrolyte. The nasal turbinate hemostatic electrode prevents the surgical electrode from causing a secondary injury to the patient during an operation process, further improving the use safety of the surgical electrode.

The present invention patent relates to a transnasal dental implant for treating upper jaws with missing teeth and severe bone atrophy, facilitating the execution of the Vanderlim technique and offering an alternative to the use of four zygomatic implants, or "quad zygoma". The implant has been developed for anchoring in any nasal turbinate anatomy, and offers the advantages of reducing surgical complexity, attending to a greater number of patients, making it possible to immediately install a complete fixed prosthesis, and improving long-term predictability and stability. The transnasal dental implant (1) has a head (11) with an upper screw thread (111) and an indicator (116); a body (12) that has a smooth section (121) and a screw thread (122); and a tip (13) with a helical slot (131).

Described herein are devices, systems, and methods for applying a tension force to various tissues. The devices may be delivered in a minimally invasive fashion and used to manipulate tissues in the nose (e.g., nasal septum, nasal turbinates), ear, and throat. Force may be maintained by the devices for a time period that allows shaping, compression, and / or approximation of tissues.

Described herein are devices, systems, and methods for applying a tension force to various tissues. The devices may be delivered in a minimally invasive fashion and used to manipulate tissues in the nose (e.g., nasal septum, nasal turbinates), ear, and throat. Force may be maintained by the devices for a time period that allows shaping, compression, and / or approximation of tissues.

Provided are a method for fabricating a human nasal turbinate-derived mesenchymal stem cell-based 3D bioprinted construct, and a use thereof, wherein the human nasal turbinate-derived mesenchymal stem cell-based, 3D bioprinted construct is advantageous over conventional mesenchymal stem cell-based, 3D bioprinted constructs in that the former can survive and proliferate stably in vitro and / or in vivo and shows high osteogenic differentiation ability as well, therefore is expected to make a great contribution to the practical use of cellular therapeutic agents.

The invention discloses a wearable device for treating eye diseases, which is characterized in that a nose root and carriage nerve stimulation unit is an electric pulse generation device and outputs an electric stimulation signal; the sienal sinus and turbinate heat auxiliary unit coincides with or partially coincides with the nose root and taxi nerve stimulation unit in position and comprises a heat conduction component; the vibration unit outputs vibration with preset frequency and vibration amplitude; the bending hinge unit is matched according to the width and radian of the nose body of a user; a power manager in the power management unit performs charging and discharging management and energy recovery management on the rechargeable battery; and the wireless signal transmission unit is distributed on the periphery of the bending hinge unit, receives program control parameters and can receive remote commands including opening or closing, parameter regulation and control, mode configuration, program over-the-air upgrading and electric quantity acquisition. According to the invention, electric pulses act on the nasal root nerves and the gliding nerves through the wearable body surface electrical stimulation technology, and the symptoms of eyeball rear pain, blurred vision and dry eye deficiency are relieved.