The invention provides a gap detection device of a large slewing bearing and belongs to the technical field of industrial measurement. The gap detection device comprises a radial error detection table, three groups of symmetrically-distributed axial error detection tables, a detection working table frame with a spiral pressing plate clamping mechanism, a slewing bearing to be detected, a controller and a displayer. Each axial error detection table comprises an axial servo motor, an axial rolling guide rail, an axial ball screw, a centering mechanism, an axial screw nut, an axial servo electric pushing rod, an axial working table plate, an axial base and an axial displacement sensor. The radial error detection table comprises a radial servo motor, a locking mechanism, a radial ball screw, a radial rolling guide rail, a radial screw nut, a radial working table plate, a radial servo electric pushing rod, a fork head, a radial base and a radial displacement sensor. The gap detection device of the large slewing bearing has the advantages of being high in detection accuracy, convenient to operate and high in detection efficiency.