The invention discloses a gas cylinder valve air tightness detection machine, which comprises a frame, a triangular fixed frame, a cabinet, a column, a pressure gauge, a support rod, a clamping part, a press, an alarm, a support panel, a fixed block, and a valve Air tightness detection device, monitor, hydraulic controller, display screen, the left end of the frame is welded to the right end of the triangular fixing frame, the column is embedded and connected to the support panel, the upper end of the support panel is attached to the lower end of the pressure gauge, a gas Gas cylinder valve airtightness testing machine Gas cylinder valve airtightness testing machine, through the hydraulic controller to open the hydraulic tank for stamping, through the pressure gauge to observe the pressure change, the detection value is displayed on the display screen, if the gas cylinder valve airtightness leaks Phenomenon, the alarm is automatically alerted, and the combination design of the transmission device, multi-point positioning and locking device is adopted, which greatly improves the inspection speed of the air tightness of the entire valve.