The invention discloses upper computer monitoring software based on a medicine bottling line real-time weighing system. According to the monitoring software, a comprehensive application platform of an upper computer system is set up on a NET development platform, a light embedded database SQLite is used as a backstage database, and the development of the intelligent software detecting along a line of the medicine bottling line is achieved. Multithread programming is supported by the NET platform, processor resources can be fully utilized, and the real-time performance of the system is improved. The SQLite database supports the service operation function and can execute multiple SQL statements in a batched mode and achieve batched, fast and frequent storage of data. In addition, a GDI and a real-time coordinate graph with weighing result drawn are adopted in the system, observation of users is facilitated, and the good interpersonal interaction function is achieved. Meanwhile, the system further provides three manners to dynamically display the measuring results, and auxiliary functions such as management and control of data storage and system self-inspecting states, inquiring and printing of historical data, user management, recipe management, system set and log books are achieved at the same time. The usability and completeness of the system are ensured.