The invention provides an air tightness detection device for a sealing piece. The device comprises a sealing unit which comprises a mounting table and a pressing mechanism, wherein the mounting tableis provided with a plugging head, when the sealing piece is located on the mounting table, the plugging head can be embedded into an opening of the sealing piece to block the opening, and the pressingmechanism is used for being matched with the sealing piece in an abutting mode and pressing a part around the opening of the sealing piece on the plugging head. The device further comprises an air supply unit which is provided with an air supply pipe, air can be output along the air supply pipe when the air supply unit is started, the air supply pipe is used for being connected with the mountingtable or the sealing piece, when the sealing unit and the sealing piece are assembled, and the air supply pipe, the sealing unit and the sealing piece define a closed containing cavity. According to the detection device provided by the scheme, when the sealing piece is assembled with the detection device, the sealing piece and the detection device can form the tightly-sealed closed containing cavity, air can be supplied into the closed containing cavity so as to realize the detection of sand holes of the sealing piece in an air tightness detection mode, the risks of false detection and missingdetection are small, the sealing unit and the sealing piece are very simple and convenient to assemble and disassemble, and the detection cost is low.