36results about How to "Guide development" patented technology

The present application discloses a method for preparing a gene chip, comprising: obtaining a first data set containing gene variation sites of a designated population; Data set; obtain a plurality of verification data sets, each of which includes a type of functionally verified gene variation site; determine multiple chip variations based on the candidate data set and the plurality of verification data sets A variety of mutation sites on the chip constitute a gene chip. The gene chip prepared by the invention contains various types of gene variation sites, realizes multiple uses of one chip, and improves the applicability of the chip.

The invention relates to the technical field of biological medicine, and particularly discloses a TCR-enriched clone as well as an acquisition method and application thereof. The TCR-enriched clone has an amino acid sequence of CAVNSYNTDKLIF_CATSREEDNTYEQYF, can provide specifically recognized epitopes for vaccine development, and can be used for guiding vaccine development and providing direction and theoretical basis for vaccine development and research.

The invention discloses a method for correcting carbon-oxygen ratio logging environment influencing factors. A Monte-Carlo method is utilized for simulating a theory relation plate between the influencing factors and a measurement value, based on the theory plate, a marker bed method is used for selecting C / O values of influenced positions and C / O values of uninfluenced positions, and a trend-surface analysis fitting method is used for carrying out linear function fitting on the influenced C / O values and the uninfluenced C / O values to obtain a fitting relation expression between the influenced C / O values and the uninfluenced C / O values. According to the method, the two influencing factors of annular fluid and gravel filling can be corrected, the method is utilized for remarkably improving the reliability of logging response values of the influenced positions, then precision for explaining and evaluating remaining oil saturation through carbon-oxygen ratio logging is improved, and the method is high in universality.

The invention provides a method for determining a formation conditions of a gas water inversion distribution relationship of a tight sandstone. The method comprises the following steps of 1) obtaininga first critical plugging pressure by performing first formation water saturation on a tight sandstone sample and performing a differential pressure natural gas charging experiment; 2) making the tight sandstone sample subjected to secondary formation water saturation anda pulsed natural gas charging experiment to obtain a second critical plugging pressure; 3) according to the first critical plugging pressure and the second critical plugging pressure, obtaining the actual critical plugging pressure of the tight sandstone sample; 4) determining the upper limit of the permeability and the upper limit of the porosity according to the actual critical plugging pressure, permeability and porosity; 5) according to the upper limit of the permeability or the upper limit of the porosity and the actual critical plugging pressure, determining the critical pore throat radius distribution when the gas water inversion is formed. The method can accurately determine the critical conditions for the formation of the gas water inversion under the actual formation conditions of tight sandstone gas reservoirs.