36results about How to "Guide development" patented technology

The invention discloses a method for calculating the permeability curve of a fractured formation based on an acoustic-electric imaging logging map, which comprises the following steps: S1, converting the color acoustic-electric imaging logging map into a grayscale image; S2, dividing the grayscale image Obtain a binary image from cracks and holes; S3, cut the binary image into several small binary images by selecting an appropriate window length and step size; S4, take a small binary image, and construct the small binary image 3D physical model of cracks and holes; S5, calculate the permeability based on the 3D physical model; S6, repeat steps S4-S5 to obtain the permeability of all small block binary maps; S7, use the permeability of all small block binary maps rate, draw the fractured formation permeability curve. Based on the color acoustic-electric imaging logging chart, the invention can accurately calculate the permeability curve of the fractured formation, make the evaluation of the fractured oil and gas reservoir more accurate, and better guide the exploration and development of the fractured oil and gas reservoir.

The present application discloses a method for preparing a gene chip, comprising: obtaining a first data set containing gene variation sites of a designated population; Data set; obtain a plurality of verification data sets, each of which includes a type of functionally verified gene variation site; determine multiple chip variations based on the candidate data set and the plurality of verification data sets A variety of mutation sites on the chip constitute a gene chip. The gene chip prepared by the invention contains various types of gene variation sites, realizes multiple uses of one chip, and improves the applicability of the chip.

The invention relates to the technical field of biological medicine and particularly discloses a TCR-enriched clonotype and an acquisition method and use thereof. The TCR-enriched clonotype has an amino acid sequence of CAVGGNEKLTF_CASSQGTGRSSPLHF, can provide specifically recognized epitopes for vaccine development, and thus can be used for guiding vaccine development and providing direction and theoretical basis for vaccine development and research.

The invention discloses a method and system for quickly analyzing remaining oil in a fracture-cavity reservoir, which includes establishing a mathematical model of the fracture-cavity reservoir; dividing the grid units of the fracture-cavity reservoir based on the mathematical model Establish a numerical model; iteratively solve the numerical model, and analyze the remaining oil of the fractured-vuggy reservoir according to the distribution of fluid pressure and saturation used to describe the fractured-vuggy reservoir; where, iteratively solving the numerical model In each iterative step at the time, it includes: extracting the oil phase pressure equation from the numerical model based on the characteristics of the grid cells; processing the oil phase pressure equation based on the algebraic multigrid algorithm to obtain the first pressure value; The first pressure value is used as an initial solution when iterating the numerical model. With this method, the remaining oil in the fracture-vuggy reservoir can be quickly and effectively analyzed.

The invention relates to the technical field of biological medicine, and particularly discloses a TCR-enriched clone as well as an acquisition method and application thereof. The TCR-enriched clone has an amino acid sequence of CAVNSYNTDKLIF_CATSREEDNTYEQYF, can provide specifically recognized epitopes for vaccine development, and can be used for guiding vaccine development and providing direction and theoretical basis for vaccine development and research.

The invention relates to the technical field of biological medicine, and particularly discloses a TCR-enriched clonotype as well as an acquisition method and application thereof. The amino acid sequence of the TCR-enriched clonotype is CAASAVGGAQKLVF_CATSRGTLYGYTF, and the TCR-enriched clonotype can provide specifically recognized epitopes for vaccine development, so that the TCR-enriched clonotype can be used for guiding vaccine development and providing direction and theoretical basis for vaccine development and research.

The invention discloses an anisotropic parameter inversion method based on base tracing lateral multi-channel constraints, including: processing seismic data, obtaining azimuth and angle stacking gathers; constructing a petrophysical model, obtaining fracture parameter logging data; The log data is de-correlated; the inversion objective function is constructed; based on the inversion objective function, the reflection coefficient sequence of the parameter to be inverted is obtained. The anisotropic parameter inversion method based on the base tracing lateral multi-trace constraint of the present invention obtains the azimuth angle stacked gather by incorporating the azimuth angle, the channel ratio of the azimuth angle stacked gather is high, and includes multiple seismic information, and more accurately Provide fracture information in the reservoir, improve the accuracy of the inversion results by decorrelating the logging data, and construct the inversion objective function by adding relevant constraints to the objective function, which improves the stability of the inversion results And horizontal continuity, so as to reduce the uncertainty of unknown parameter estimation.

The invention discloses a method for correcting carbon-oxygen ratio logging environment influencing factors. A Monte-Carlo method is utilized for simulating a theory relation plate between the influencing factors and a measurement value, based on the theory plate, a marker bed method is used for selecting C / O values of influenced positions and C / O values of uninfluenced positions, and a trend-surface analysis fitting method is used for carrying out linear function fitting on the influenced C / O values and the uninfluenced C / O values to obtain a fitting relation expression between the influenced C / O values and the uninfluenced C / O values. According to the method, the two influencing factors of annular fluid and gravel filling can be corrected, the method is utilized for remarkably improving the reliability of logging response values of the influenced positions, then precision for explaining and evaluating remaining oil saturation through carbon-oxygen ratio logging is improved, and the method is high in universality.

The present invention provides an optimal design method of an engine cooling system. The design method uses one-dimensional fluid simulation technology to analyze the flow of the cooling system, and includes the following steps: (1) collecting data related to cooling system components and performing parameterized processing; 2) Build a one-dimensional model; (3) Carry out simulation calculations under different working conditions; (4) Analyze the calculation results, and carry out routine optimization design of the cooling system according to the calculation results. The present invention obtains the optimal matching parameters of the engine cooling system by simulating the pressure distribution, flow distribution, flow resistance of each component, and temperature change of the cooling fluid in the warm-up condition at the initial stage of design, and can better guide the design of the cooling system and development to improve development efficiency and save test costs.

The invention provides a device for testing underwater brisance of an explosive, comprising a pressure device and an explosion chamber; wherein, the explosion chamber comprises a tube upper seal, a tube body, a tube lower seal; when brisance is tested, the inside of a tube chamber is sealed, an explosion sample, a primer, a sheet steel and a lead block are arranged inside the tube chamber; water is injected to submerge the explosive sample, gas is injected into a chamber above the water; pressure is increased to the pressure of simulative corresponding positions under the water; then the explosive is detonated, the length of the lead block before and after the explosion, in such a way, simulative brisance in case of explosion under the same condition under the water can be worked out. Since brisance is one of the important parameters for measuring explosion property of the explosive, the measurement of the brisance is conducive to further guiding development on under water blasting and the explosive therefore. The device of the invention can adopt the simulative deepwater environment to measure brisance of the explosive at different water depths, thus solving the problem that measurement of the brisance in case of underwater blasting is difficult.

The invention provides a method for determining a formation conditions of a gas water inversion distribution relationship of a tight sandstone. The method comprises the following steps of 1) obtaininga first critical plugging pressure by performing first formation water saturation on a tight sandstone sample and performing a differential pressure natural gas charging experiment; 2) making the tight sandstone sample subjected to secondary formation water saturation anda pulsed natural gas charging experiment to obtain a second critical plugging pressure; 3) according to the first critical plugging pressure and the second critical plugging pressure, obtaining the actual critical plugging pressure of the tight sandstone sample; 4) determining the upper limit of the permeability and the upper limit of the porosity according to the actual critical plugging pressure, permeability and porosity; 5) according to the upper limit of the permeability or the upper limit of the porosity and the actual critical plugging pressure, determining the critical pore throat radius distribution when the gas water inversion is formed. The method can accurately determine the critical conditions for the formation of the gas water inversion under the actual formation conditions of tight sandstone gas reservoirs.

The invention relates to the technical field of biological medicine, and particularly discloses a TCR-enriched clonotype as well as an acquisition method and application thereof. The amino acid sequence of the TCR-enriched clonotype is CASSSGGSYIPTF_CASSLAGGHETQYF, and the TCR-enriched clonotype can provide specifically recognized epitopes for vaccine development, so that the TCR-enriched clonotype can be used for guiding vaccine development and providing direction and theoretical basis for vaccine development and research.