The invention relates to an anti-floating method for a thin-walled square box in a flat slab floor. The anti-floating method comprises the following steps that firstly, construction is prepared; secondly, the square box is mounted, specifically, a bottom plate rib is mounted on a bottom plate formwork, supporting steel pipe frames are arranged below the bottom plate formwork, then the square box is hoisted onto the bottom plate rib through a hoisting basket, cushion blocks are placed on the bottom plate rib, and the square box is lifted and put onto the cushion blocks; and thirdly, the thin-walled square box is subjected to anti-floating fixing, specifically, two steel bars are arranged on the square box, the two steel bars are arranged in a crossed mode to be in a cross shape, then the steel bars and the supporting steel pipe frames below the bottom plate formwork are fixed in a bound mode through steel wires, reinforcing bars longitudinally and transversely arranged are arranged on the upper portions of the two steel bars, and at the four edges of the square box, the two cross-shaped steel bars which press the box tops are fixed to the supporting steel pipe frames in a bound mode through the steel wires. The problem of upward-floating of the thin-walled square box in the concrete pouring and vibrating processes is effectively solved, the construction efficiency is improved, the construction progress is accelerated, and a quite good anti-floating effect is achieved, so that the construction progress is accelerated. Certain reference and popularization significance is achieved for a similar construction technology.