The present invention relates to a saponin-containing composite type hydrate anti-agglomerant, which comprises a saponin plant extract and an auxiliary anti-agglomerant. Compared to the existing anti-agglomerant, the saponin-containing composite type hydrate anti-agglomerant of the present invention has the following characteristics that: an initial generation state of a hydrate can be effectively controlled so as to effectively avoid possibly-generated hydrate aggregation when water content is high, such that dynamic control of the hydrate is easily achieved, it is ensured that hydrate crystals exist in an oil-gas-water multiphase mixing transportation pipeline in a small particle form, and accumulation and deposition phenomena can not be generated so as to effectively solve the flow safety assurance problem of the multiphase mixing transportation pipeline; the saponin plant extract in the hydrate anti-agglomerant is a nature plant extract, does not have toxicity, and is easily biodegraded, and the selected raw materials of the auxiliary anti-agglomerant are non-toxic; and the hydrate anti-agglomerant has characteristics of no toxicity, economy, environment protection, good action effect, uniform generated hydrate particle distribution, and the like.