A power saving method and apparatus for wireless optical mouse is disclosed, the apparatus comprising: a micro control unit (MCU), for controlling the operation of a sensor integrated circuit (IC) of an optical sensor of the wireless optical mouse; a wireless transceiver module, connected to the MCU, for transmitting/receiving electronic signals to/from a corresponding wireless interface of a computer; an oscillation frequency control circuit, for switching the operation frequency of the sensor IC so as to enable the same to be defined by a RC oscillation circuit of the sensor IC while the sensor IC being in a sleep mode, and switching the operation frequency of the sensor IC so as to enable the same to be defined by a crystal oscillation circuit; a light emitting diode (LED) control circuit, for controlling the activation of a LED and thus enabling the motion of the wireless optical mouse to be detected; a sensor cell control circuit, for enabling only one of a plurality sensor cells of a sensor cell array while the sensor IC being in the sleep mode, and enabling every sensor cell of the sensor cell array while the sensor IC being in a working mode; and a mode switch circuit, for controlling the mode the sensor IC to be switched between the sleep mode and the working mode according to the output of the sensor cell control circuit.