Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

15 results about "Dose estimation" patented technology

Real-time verification of radiotherapy delivery system operation

PendingUS20250332449A1X-ray/gamma-ray/particle-irradiation therapyRadiologyDose estimation
Disclosed herein are methods for verifying whether a radiotherapy delivery system is delivering therapeutic radiation to the target region in accordance with instructions from the radiotherapy system controller. The methods utilize imaging data acquired by a radiation imager (e.g., MV detector) that is located across from (e.g., opposite) the therapeutic radiation source. In some variations, the imaging data from the radiation imager is used to determine whether the components of the radiation beam-shaping assembly are in the location specified by the controller instructions. Also disclosed herein are methods for verifying whether the radiation beams emitted by the therapeutic radiation source intersect with a target region and / or a contour around the target region, including methods for determining delivered fluence and dose estimates.
Owner:REFLEXION MEDICAL INC

Nucleus imaging-based voxel-level radionuclide dose estimation method and computer device

ActiveCN120661851BVoxelDoses rate
The application provides a voxel-level radionuclide dose estimation method based on radionuclide imaging and a computer device. The method comprises the following steps: acquiring X-ray structural images and gamma-ray functional images at a single time point or multiple time points; segmenting a region of interest to obtain multiple sub-regions of interest; performing regional partial volume correction on the multiple sub-regions of interest of the gamma-ray functional images to obtain corrected gamma-ray functional images; performing registration on the corrected gamma-ray functional images; performing activity-dose rate conversion on the registration results to obtain a dose rate, and performing voxel-level curve fitting and integration on the dose rate to obtain an absorbed dose distribution result, and determining the absorbed dose of each sub-region of interest based on the absorbed dose result. The application can reduce the influence of the partial volume effect on the resolution of radionuclide imaging, improve the accuracy of radionuclide image registration, and further improve the accuracy of radionuclide absorbed dose estimation.
Owner:UNIV OF MACAU

Multifunctional intelligent patient medicine feeding device for clinical nursing

The invention relates to the technical field of medical instruments, and discloses an operation table, electric rotating tables are arranged on the two sides of one end of the top of the operation table, bases are fixedly connected to the tops of the electric rotating tables, and first brake motors are fixedly connected to one sides of the bases; the output end of the first brake motor penetrates through the base and is fixedly connected with a large arm, the large arm is rotationally connected with the inner wall of the first brake motor, one side of the large arm is fixedly connected with a second brake motor, and the output end of the second brake motor penetrates through the large arm and is fixedly connected with a small arm. Solid and liquid medicines are accurately metered through the medicine feeding assembly, the solid medicines are accurately clamped by a pneumatic finger and quantitatively scooped by a latex spoon, and the liquid medicines are accurately extracted and injected through a needle cylinder, so that the deviation possibly caused by manual dose estimation is avoided, a patient is ensured to take a correct dose, and the treatment risk caused by a wrong dose is reduced.
Owner:THE 3RD AFFILIATED HOSPITAL OF CHANGCHUN UNIVERSITY OF CHINESE MEDICINE

System for calculating estimated spray inhaled dose using turbidity image and photoplethysmogram measurement technique and control method therefor

PCT designated stageWO2025258938A1Drug and medicationsMedical devicesInhaled drugPharmaceutical drug
The present disclosure relates to: a system for calculating an estimated spray inhaled dose by using a turbidity image and a photoplethysmogram (PPG) measurement technique; and a control method therefor. According to the present disclosure, an inhaled drug dose can be estimated by using a change in pulse waves measured by a PPG measurement technique and the turbidity of an image captured of a drug that cannot be properly inhaled by a patient and thus disappears into the air in a mist without being administered, and feedback and notification on the inhaled drug dose can be given such that a user can easily know the inhaled dose of the drug relative to the total amount of the drug, and thus user convenience can be improved.
Owner:THE CATHOLIC UNIV OF KOREA IND ACADEMIC COOP FOUND

Intelligent drug delivery monitoring system for nano-drug delivery carrier

The invention relates to the technical field of delivery monitoring, in particular to a drug delivery intelligent monitoring system for a nano-drug delivery carrier, which comprises an acquisition module, a decoupling module, an extraction module, a construction module, an identification module, an adjustment module and an alarm module. According to the method, high-precision drug delivery monitoring under high magnetic field interference is achieved by decomposing and quantitatively compensating multi-source time sequence signals, the system eliminates the influence of exogenous disturbance on a steady-state index, disturbance response is used for prediction and correction, a judgment strategy is adjusted by taking historical disturbance as a benchmark, and the accuracy of drug delivery monitoring is improved. False report and missing report are obviously reduced, and the confidence of positioning and dose estimation is improved, so that the precision and reliability of drug delivery monitoring are maintained in complex interference scenes such as transient magnetic pulse, continuous high field or severe fluctuation of blood flow; the problems that the drug positioning precision is reduced and the dose release is unbalanced due to the fact that the delivery channel state cannot be accurately recognized in a high electromagnetic interference environment are effectively solved.
Owner:SHENZHEN CHILDRENS HOSPITAL

Voxel-level nuclide dose estimation method based on nuclide imaging and computer equipment

The invention provides a voxel-level nuclide dose estimation method based on nuclide imaging and computer equipment. Comprising the following steps: acquiring an X-ray structure image and a gamma-ray function image at a single time point or a plurality of time points; segmenting the region of interest to obtain a plurality of sub-regions of interest, and performing region-level partial volume correction on the plurality of sub-regions of interest of the gamma-ray functional image to obtain a corrected gamma-ray functional image; carrying out registration on the corrected gamma ray function image; and performing activity-dose rate conversion on the registration result to obtain a dose rate, performing voxel-level curve fitting and integration on the dose rate to obtain an absorbed dose distribution result, and determining the absorbed dose of each sub-region of interest based on the absorbed dose result. According to the method and the device, the influence of partial volume effect on nuclide imaging resolution can be reduced, so that the nuclide image registration precision is improved, and the radionuclide absorbed dose estimation precision is improved.
Owner:UNIV OF MACAU

Tumor dose monitoring method and system based on radiotherapy

The invention discloses a tumor dose monitoring method and system based on radiotherapy, and relates to the technical field of medical care informatics. The tumor dose monitoring method and system based on radiotherapy comprises the following steps: S1, acquiring tumor dose data by using an implantable optical fiber dose detector, and performing data cleaning and normalization processing on the tumor dose data; s2, performing preliminary dose estimation and physical modeling compensation on the preprocessed tumor dose data, and constructing a three-dimensional convolutional neural network model to refine three-dimensional dose distribution; s3, analyzing deviation intensity according to a comparison result of the tumor dose evaluation value and the reference body surface dose, performing grading judgment on the deviation intensity, generating an adjustment suggestion, and forming a control flow for regulating closed-loop feedback; and S4, focusing the deep estimation points of the target region to count the deviation distribution characteristics, and generating structured correction data for subsequent reconstruction input and risk prompt generation. The problem that in-vivo tumor area three-dimensional dose distribution cannot be accurately reduced through body surface dose monitoring is solved.
Owner:THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIV

Method, device and medium for environmental impact assessment of radioactive wastewater discharge of nuclear medicine department

ActiveCN121115082BWastewaterDose estimation
The application discloses a kind of nuclear medicine department radioactive sewage discharge environmental impact assessment method, equipment and medium, it is related to radiation environmental impact assessment technical field, solve the current radiation environmental impact assessment technology cannot provide the influence of different discharge routes to public dose Technical problems, its technical scheme main point is to the condition that radioactive nuclide-containing wastewater is discharged into urban sewage pipe network, the public dose after radioactive nuclide-containing wastewater is discharged into landscape water and receiving water body is calculated respectively, and the deposition concentration on the surface of vegetation soil and the deposition concentration on the surface of crop soil are redefined, improve the accuracy of public dose estimation, can simply and accurately evaluate the radiation dose caused to public.
Owner:CHINA INST FOR RADIATION PROTECTION

Radiation dose estimation method and device

Embodiments of the present invention relate to a radiation dose estimation method and apparatus, comprising the following steps: scanning a target body according to a preset interval thickness to obtain scan data of different sections of the target body and parameters corresponding to the scan data; performing three-dimensional reconstruction and two-dimensional conversion on the scan data to obtain a registered dataset; performing tissue segmentation on the dataset to obtain a segmented dataset; comparing the segmented dataset with preset standard data to obtain the element types and densities contained in each tissue; and simulating the scanning imaging process using the target body parameters, scanning positioning parameters, and scanning setting parameters, along with the comparison results, to calculate the radiation dose received by each tissue during the scan. Embodiments of the present invention analyze data information obtained by CBCT to estimate the radiation dose, providing a data basis for parameter setting and dose usage during the CBCT scanning process.
Owner:PEKING UNIV SCHOOL OF STOMATOLOGY

Method, equipment and medium for evaluating environmental influence of radioactive sewage discharge in nuclear medicine department

The invention discloses a radioactive sewage discharge environment influence evaluation method, equipment and a medium for the nuclear medicine department, relates to the technical field of radiation environment influence evaluation, and solves the technical problem that the current radiation environment influence evaluation technology cannot provide the influence on the public dosage under different discharge ways. According to the technical scheme, the method is characterized in that aiming at the condition that the radionuclide-containing wastewater is discharged into a town sewage pipe network, public doses of the radionuclide-containing wastewater as landscape water and after the radionuclide-containing wastewater is discharged into a receiving water body are calculated respectively, and the deposition concentration of the vegetation soil surface and the deposition concentration of the crop soil surface are redefined; the accuracy of public dose estimation is improved, and the radiation dose caused to the public can be simply, conveniently and accurately evaluated.
Owner:CHINA INST FOR RADIATION PROTECTION

Rapid population biological dose evaluation system used under large-scale ionizing radiation exposure condition

The invention relates to the technical field of nuclear radiation evaluation, in particular to a rapid population biological dose evaluation system used under the condition of large-scale ionizing radiation exposure. According to the rapid evaluation method, the analysis efficiency can be improved, the dose can be accurately estimated, and the rapid and effective method can replace manual DCA dose estimation. The method and the curve can be potentially applied to a triage mode and serve as an alternative scheme for manual analysis under large-scale radioactive events, and rapid dose evaluation is achieved.
Owner:CHINA INST FOR RADIATION PROTECTION

Label-free imaging method for lymphocyte radiation dose estimation

The present application relates to the technical field of biological dose estimation, and particularly relates to a lymphocyte radiation dose estimation method based on label-free imaging. The method comprises the following steps: collecting SRS images of irradiated lymphocytes; based on an improved U-Net deep learning model, performing automatic segmentation of micronuclei to obtain segmented SRS images; obtaining multiple features of each cell; obtaining a one-dimensional fusion feature vector of each cell; training a dose prediction model to obtain a trained dose prediction model; inputting the one-dimensional fusion feature vector corresponding to the lymphocyte to be predicted into the trained dose prediction model to obtain a radiation dose. The present application first establishes a quantitative mapping model from SRS multi-dimensional features to radiation dose, and realizes accurate estimation of the radiation dose.
Owner:XIDIAN UNIV

A tumor dose monitoring method and system based on radiotherapy

The present invention discloses a method and system for monitoring tumor dose based on radiotherapy, which relates to the technical field of medical care informatics. The method and system for monitoring tumor dose based on radiotherapy include the following steps: S1, using an implantable fiber optic dose detector to collect tumor dose data, and performing data cleaning and normalization processing on the tumor dose data; S2, performing preliminary dose estimation and physical modeling compensation on the pre-processed tumor dose data, and constructing a three-dimensional convolutional neural network model to refine the three-dimensional dose distribution; S3, analyzing the deviation intensity based on the comparison result between the tumor dose assessment value and the reference surface dose, making a graded judgment on the deviation intensity and generating adjustment suggestions, forming a control process for closed-loop feedback; S4, focusing on the statistical deviation distribution characteristics of the deep estimation point of the target area, and generating structured correction data for subsequent reconstruction input and risk prompt generation. It solves the problem that surface dose monitoring is difficult to accurately restore the three-dimensional dose distribution of the tumor area in the body.
Owner:THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIV

Dose estimation for the irradiation of an object

ActiveDE102020205996B4Image enhancementImage analysisDose estimationIrradiation
Computer-implemented method for dose estimation for the irradiation of an object (5) with ionizing radiation, wherein a three-dimensional model with a total number (9) of spatial elements is provided on a storage element (4), wherein the model specifies a material composition of the object (5) for each spatial element, and by means of a computing unit (3) - for a connected neighborhood (10) of spatial elements of the total number (9) of spatial elements, depending on the respective material compositions of all spatial elements of the neighborhood of the model, a neighborhood material composition is determined by averaging or homogeneously approximating one or more material parameters of the respective material compositions; - a radiation dose for the neighborhood (10) with respect to ionizing radiation is determined by means of a simulation depending on the neighborhood material composition; and - a dose distribution for the object (5) with respect to ionizing radiation is determined based on the radiation dose for the neighborhood (10).
Owner:SIEMENS HEALTHINEERS AG

Method and equipment for calculating injection dose of periinsulin preparation

The invention discloses a method and equipment for calculating the injection dose of a periinsulin preparation. The method comprises the following steps: acquiring a single injection pharmacokinetic model of the periinsulin preparation, historical injection information of a patient using the periinsulin preparation, a fasting blood glucose value monitored during the period of using the periinsulin preparation by the patient and a dose estimated value of the injection; according to the acquired single injection pharmacokinetic model, the historical injection information, the fasting blood glucose value and the dose estimation value, predicting fasting blood glucose of the patient in a next week after the patient injects the periinsulin preparation according to the dose estimation value; according to whether the fasting blood glucose of the next week is within the fasting blood glucose target range of the patient or not, whether the dose estimation value needs to be adjusted or not is judged, and the dose estimation value is adjusted based on the judgment result so that the adjusted injection dose estimation value can meet the requirement. The injection dosage can enable a patient to reach a steady state as soon as possible, and the injection dosage can be compatible with occasionally irregular injection modes.
Owner:PEKING UNIVERSITY FIRST HOSPITAL (PEKING UNIVERSITY FIRST CLINICAL MEDICAL COLLEGE)