88 results about "Electrophoretic mobilities" patented technology

The invention provides an electrophoretic medium comprising at least two types of particles having substantially the same electrophoretic mobility but differing colors. The invention also provides article of manufacture comprising a layer of a solid electro-optic medium, a first adhesive layer on one surface of the electro-optic medium, a release sheet covering the first adhesive layer, and a second adhesive layer on an opposed second surface of the electro-optic medium.

The present invention provides novel microfluidic devices and methods for performing pulsed field mobility shift assays in microfluidic devices. In particular the devices and methods of the invention utilize differences between electrophoretic mobilities (e.g., as between reactants and products, especially in non-fluorogenic reactions) in order to separate the species and thus analyze the reaction.

The present invention provides a novel class of fluorescent cyanine dye compounds that are modified at one of the hetercyclic ring nitrogen atoms with a mobility-modifying moiety that permits the electrophoretic mobilities of polynucleotides labeled with the mobility-modifying cyanine dyes to be adjusted or tuned in a predictable fashion while retaining enzymatic activity. The ability to predictably tune the relative electrophoretic mobilities of the dyes permits the creation of sets of mobility-matched fluorescent dyes of a variety of structures for a variety of applications, including fluorescence-based 4-color nucleic acid sequencing reactions.

A multi-color electrophoretic medium contains first, second and third species of particles, the particles having substantially non-overlapping electrophoretic mobilities and bring of three different colors. The particles are dispersed in a fluid having a fourth color. A method for driving such a display is also described.

An apparatus and method are disclosed for determining electrophoretic mobility using scattering light phase analysis comprising emitting a laser light along a path and transmitting a first portion of the laser light and reflecting a second portion of the laser light. The apparatus and method can also comprise deflecting one of the first and second portions of the laser in response to a drive signal, holding a sample to receive at least one of the first and second portions of the laser light under an electric field and output a composite light wave, outputting a photopulse signal based on the composite light wave, and measuring the electrophoretic mobility of the sample based on a phase shift analysis using cross-correlation of the photopulse signal with the drive signal.

Methods, compositions, kits, and a system are disclosed for detecting one or more analytes in a sample. A mixture comprising the (i) sample, (ii) a first binding reagent comprising a cleavage-inducing moiety and a first binding agent specific for an analyte, and (ii) one or more electrophoretic probes each having a second binding agent is subjected to conditions under which binding of respective binding agents occurs. The interaction between the binding agents and the analyte brings the cleavage-inducing moiety within a proximity effective for cleaving a cleavable linkage tethering an electrophoretic tag to the second binding agent, thereby releasing the tag for electrophoretic separation. Separation of different tags occurs by virtue of their distinct electrophoretic mobilities. After separation, a signal amplification moiety on each tag is activated to generate a signal to indicate the presence of a particular analyte in the sample.

An aqueous polishing composition comprising (A) abrasive particles which are positively charged when dispersed in an aqueous medium having a pH in the range of from 3 to 9 as evidenced by the electrophoretic mobility; (B) water-soluble and water-dispersible hydroxy group containing components selected from (b1) aliphatic and cycloaliphatic hydroxycarboxylic acids, wherein the molar ratio of hydroxy groups to carboxylic acid groups is at least 1; (b2) esters and lactones of the hydroxycarboxylic acids (b1) having at least one hydroxy group; and (b3) mixtures thereof; and (C) water-soluble and water-dispersible polymer components selected from (c1) linear and branched alkylene oxide polymers; (c2) linear and branched, aliphatic and cycloaliphatic poly(N-vinylamide) polymers; and (c3) cationic polymeric flocculents having a weight average molecular weight of less than 100,000 Dalton.; and a process for polishing substrate materials for electrical, mechanical and optical devices.

A resin emulsion with high electrophoretic mobility for cathode electrophoretic paint is prepared from the linear polyamine modified monocycle oxide, amine modified biphenolic epoxy resin, and full-enclosed polyisocyanate as cross-linking agent through proportionally mixing, chemically, reacting, neutralizing, with organic acid and dispersing in water. Its advantages are high electrophoretic coating productivity and high anticorrosion power.

The invention provides an electrophoresis cassette, methods for making the electrophoresis cassette, and method of fractionating analytes from a sample based upon electrophoretic mobility in a single application of the sample to an electrophoretic system.

The present invention relates to cell separation using microfabricated devices. In particular, the present invention provides methods and devices for separation of sperm from biological materials, such as other cells and molecular species, in a cell mixture in a microfabricated device through the use of electroosmotic flow, electrophoretic mobility, pressure gradient, differential adhesion, and/or combinations thereof.

The invention relates to an operation mode of electrophoresis, which separates and/or fractionates particles of differentiated electrophoretic mobility. More specifically, the invention relates to isotachophoresis (ITP), including free-flow and capillary isotachophoresis, and provides novel electrophoresis methods, as well as kits and devices for carrying out such methods.

An aqueous polishing composition having a pH of 3 to 11 and comprising (A) abrasive particles which are positively charged when dispersed in an aqueous medium free from component (B) and of a pH of 3 to 9 as evidenced by the electrophoretic mobility; (B) anionic phosphate dispersing agents; and (C) a polyhydric alcohol component selected from the group consisting of (c1) water-soluble and water-dispersible, aliphatic and cycloaliphatic, monomeric, dimeric and oligomeric polyols having at least 4 hydroxy groups; (c2) a mixture consisting of (c21) water-soluble and water-dispersible, aliphatic and cycloaliphatic polyols having at least 2 hydroxy groups; and (c22) water-soluble or water-dispersible polymers selected from linear and branched alkylene oxide homopolymers and copolymers (c221); and linear and branched, aliphatic and cycloaliphatic poly(N-vinylamide) homopolymers and copolymers (c222); and (c3) mixtures of (c1) and (c2); and a process for polishing substrates for electrical, mechanical and optical devices.

A method and device are provided for concentrating and separating materials in fluids within a fluidic device having a fluid conduit such as a channel or capillary. The concentration is achieved by balancing the electrophoretic velocity of a material against the bulk flow of fluid in the presence of a temperature gradient. An additive is added to the fluid which interacts with the material and which modifies the normal electrophoretic mobility of the material. Using an appropriate fluid, the temperature gradient can generate a corresponding gradient in the electrophoretic velocity so that the electrophoretic and bulk velocities sum to zero at a unique position along the conduit and the material will be focused at that position. The method and device may be adapted for use with a variety of materials including fluorescent dyes, amino acids, proteins, DNA and to concentrate a dilute material.

The invention discloses imidazole salt type cationic polyurethane and a preparation method thereof. The preparation method comprises the following steps: 1) mixing 1mol of dibromoneopentyl glycol with 2mol of imidazole compound to react and obtain imidazole salt glycol; and 2) mixing 1-10mol of imidazole salt glycol, 1-10mol of long-chain glycol with the weight average molecular weight of 100-2000, 1.8-20mol of diisocyanate, tetrahydrofuran and 2-3 drops of catalyst to react in the atmosphere of nitrogen and obtain the cationic polyurethane, wherein the molecular structure of the imidazole salt type cationic polyurethane is AxByCz, A is imidazole salt glycol, B is diisocyanate, C is long-chain glycol; and (x+z)/y=1.0-1.1; and the ratio of x to z is 0.1-10.0. In the preparation method of the invention, the charged functional groups of glycol are expanded, imidazole salt glycol ionic liquid is introduced and the imidazole salt type cationic polyurethane is prepared; and the electrophoretic mobility can not be damaged by acid or base. Cationic polyurethanes with unequal electric charges can be prepared by adjusting the proportion of imidazole salt glycol; and the cationic polyurethane can be coated on elements through electrostatic adsorption, thus better protecting and stabilizing the base material.