The invention relates to
medicine and veterinary science and can be used for treating diseases associated with changes of the qualitative and / quantitative composition of blood
extracellular DNA, namely generalised infection diseases provoked by
bacteria, diseases provoked by fungi and
protozoa, atherosclerosis, pancreatic diabetes, allergic diseases associated with
delayed response hypersensitivity and diseases due to
somatic cell gene mutations. The inventive method for treating diseases associated with modifications of the qualitative and / or quantitative composition of blood
extracellular DNA, namely generalised infection diseases provoked by
bacteria, diseases provoked by fungi and
protozoa, atherosclerosis, pancreatic diabetes, allergic diseases associated with
delayed response hypersensitivity and diseases due to
somatic cell gene mutations consists in injecting an agent destroying blood
extracellular DNA. DNAse
enzyme injected into a
systemic blood circulation in doses which modify the electrophoretic profile of the blood
extracellular DNA definable by pulse-
electrophoresis can be used in the form of an agent destroying said blood
extracellular DNA. Said DNAse
enzyme can be injected in doses and at regimes ensuring the level of a
blood plasma DNA-hydrolytic activity which is measured in the
blood plasma and is higher than 150 Kunz units per litre of
plasma during a total time higher than 12 hours a day. The inventive method makes it possible to develop a high-efficient and low-toxic method for treating diseases associated with modifications of qualitative and / or quantitative composition of blood
extracellular DNA individually or in combination thereof.