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106 results about "Infra-orbital nerve" patented technology

After the maxillary nerve enters the infraorbital canal, the nerve is frequently called the infraorbital nerve. This nerve innervates (sensory) the lower eyelid, upper lip, and part of the nasal vestibule and exits the infraorbital foramen of the maxilla.

Stimulation for treating brain events and other conditions

Apparatus for treatment is provided, including one or more electrodes, configured to be applied to a site of a subject, and adverse cerebrovascular condition treatment functionality. The functionality comprises a control unit configured to drive the one or more electrodes to apply electrical stimulation to the site during a plurality of stimulation periods which includes at least first and last stimulation periods, set an inter-period interval between initiation of the first stimulation period and initiation of the last stimulation period to be at least 24 hours, and configure the stimulation during the first and last stimulation periods to induce at least one neuroprotective occurrence selected from the group consisting of: an increase in cerebral blood flow (CBF) of the subject, and a release of one or more neuroprotective substances. The site is selected from the group consisting of: a sphenopalatine ganglion (SPG), a greater palatine nerve, a lesser palatine nerve, a sphenopalatine nerve, a communicating branch between a maxillary nerve and an SPG, an otic ganglion, an afferent fiber going into the otic ganglion, an efferent fiber going out of the otic ganglion, an infraorbital nerve, a vidian nerve, a greater superficial petrosal nerve, and a lesser deep petrosal nerve. Additional embodiments are also described.
Owner:BRAINSGATE LTD

Stimulation for treating brain events and other conditions

ActiveUS8055347B2Increase cerebral blood flowHarmful conditionSpinal electrodesArtificial respirationDiseaseDeep petrosal nerve
Apparatus for treatment is provided, including one or more electrodes, configured to be applied to a site of a subject, and adverse cerebrovascular condition treatment functionality. The functionality comprises a control unit configured to drive the one or more electrodes to apply electrical stimulation to the site during a plurality of stimulation periods which includes at least first and last stimulation periods, set an inter-period interval between initiation of the first stimulation period and initiation of the last stimulation period to be at least 24 hours, and configure the stimulation during the first and last stimulation periods to induce at least one neuroprotective occurrence selected from the group consisting of: an increase in cerebral blood flow (CBF) of the subject, and a release of one or more neuroprotective substances. The site is selected from the group consisting of: a sphenopalatine ganglion (SPG), a greater palatine nerve, a lesser palatine nerve, a sphenopalatine nerve, a communicating branch between a maxillary nerve and an SPG, an otic ganglion, an afferent fiber going into the otic ganglion, an efferent fiber going out of the otic ganglion, an infraorbital nerve, a vidian nerve, a greater superficial petrosal nerve, and a lesser deep petrosal nerve. Additional embodiments are also described.
Owner:BRAINSGATE LTD

DNP and DNP Prodrug Treatment of Neuromuscular, Neurodegenerative, Autoimmune, Developmental, Traumatic Brain Injury, Concussion, Dry Eye Disease, Hearing Loss and/or Metabolic Diseases

A composition and method of treatment of neuromuscular, neuromuscular degenerative, neurodegenerative, autoimmune, developmental, traumatic, hearing loss related, and/or metabolic diseases, including spinal muscular atrophy (SMA) syndrome (SMA1, SMA2, SMA3, and SMA4, also called Type I, II, III and IV), traumatic brain injury (TBI), concussion, keratoconjunctivitis sicca (Dry Eye Disease), glaucoma, Sjogren's syndrome, rheumatoid arthritis, post-LASIK surgery, anti-depressants use, Wolfram Syndrome, and Wolcott-Rallison syndrome. The composition is selected from the group consisting of 2,3-DNP, 2,4-DNP, 2,5-DNP, 2,6-DNP, 3,4-DNP, or 3,5-DNP, bipartite 2,3-dinitrophenol, 2,4-dinitrophenol, 2,5-dinitrophenol, 2,6-dinitrophenol, 3,4-dinitrophenol, or 3,5-dinitrophenol (2,3-DNP, 2,4-DNP, 2,5-DNP, 2,6-DNP, 3,4-DNP, or 3,5-DNP) prodrugs; Gemini prodrugs, bioprecursor molecules, and combinations thereof. A dose of the composition for treatment of neurodegenerative diseases may be from about 0.01 mg/kg of body weight to about 50 mg/kg of body weight of the patient in need of treatment. A dose of the composition for treatment of metabolic diseases may be from about 1 mg/70 kg of body weight to about 100 mg/70 kg of body weight of the patient in need of treatment, and a maximum dose per day is about 200 mg/70 kg of body weight of the patient in need of treatment.
Owner:MITOCHON PHARMA INC +1

Multi-angle locking and fixing humerus straight type interlocking intramedullary pin

PendingCN110934630AHigh strengthAvoid slight misalignmentInternal osteosythesisSurgical riskBone humerus
The invention discloses a multi-angle locking and fixing humerus straight type interlocking intramedullary pin. The multi-angle locking and fixing humerus straight type interlocking intramedullary pincomprises a humerus intramedullary pin main pin, wherein the humerus intramedullary pin main pin adopts a hollow structure, and comprises a near end intramedullary pin, a far end intramedullary pin and a connecting section; the diameter of the near end intramedullary pin is greater than that of the far end intramedullary pin; one end of the near end intramedullary pin is in transition connectionwith the far end intramedullary pin through the connecting section, and the inner part of the other end of the near end intramedullary pin is connected with a terminal cap; the near end intramedullarypin, the far end intramedullary pin and the connecting section adopt an integrated structure; the diameter of the near end intramedullary pin is 9mm, a plurality of pin holes are formed in the near end intramedullary pin and the far end intramedullary pin; bone screws are arranged in the pin holes; and the bone screws in the near end intramedullary pin are multi-angle screws. According to the multi-angle locking and fixing humerus straight type interlocking intramedullary pin disclosed by the invention, the opportunity of selecting appropriate humerus intramedullary pin main pin according tohumerus individual dissection differences is increased, and the operation risk of generating fracture of humeral head and injury of axillary nerve caused by that an opening in the humerus head part islarge is reduced.
Owner:上海伯塔医疗器械有限公司

Neuromodulation for treatment of retinal, choroidal and optic nerve disorders and/or dysregulated reduced ocular blood flow (OBF)

Disclosed are devices, systems and methods for non-invasive neuromodulation system for treating inherited or acquired retinal, choroidal and optic nerve disorders caused by acute or chronic dysregulated reduced ocular blood flow (OBF) and / or energy failure by up regulation of trigemino-vascular system (TVS), trigeminal autonomic brain reflexes (TABRs) and pancreatic trigemino-vagal reflex (TVR) through stimulation of ophthalmic nerve (V1), more specifically but not limited to SP, and CGRP containing unmyelinated C nerve fibers. The invention, in some embodiments thereof, relates to the methods for enhancing SP and CGRP expression in neurovascular tissue of the retina and choroid. The invention, in some embodiments thereof, relates to SP / CGRP mediated pathways, including those involved in vasodilatation, augmentation of OBF, RPE proliferation, prevention of apoptosis, suppressing neuroinflammation, promoting migration and differentiation of vascular endothelial cells as well as mobilization of endogenous mesenchymal stem cells (EMSCs) from the bone marrow to the circulation to accelerate tissue repair. The site of stimulation of V1 nerve includes but not limited to; nasal vestibule nasal bridge, forehead, and upper eyelids. Additionally or alternatively, the subject's sympathetic nervous system (SNS) is down regulated by sympatholytic agents specifically antioxidants. The subject's TVS and autonomic nervous system (ANS) are modulated in a manner that is effective to treat the subject for retinal, choroidal and / or optic nerve disorders. In some embodiments, the devices are handheld, portable with nose supported, having one or more intra-nasal or extra-nasal application heads. The signal can include vibration, chemical, ultrasonic, optical, electrical, hybrid electro-optical or combination of two or more of these types of stimuli. The invention, in some embodiments thereof, relates to a method for decreasing vascular resistance, enhancing vasodilatation in ophthalmic artery and its branches by the release of Vasoactive intestinal peptide (VIP),substance P and CGRP thereof increasing OBF to the retina, choroid and optic nerve in subject's with acute or chronic dysregulated, reduced OBF. The invention, in some embodiments thereof, is also related to the methods for improving delivery of oxygen, glucose, vitamin A, humoral mediators, growth factors, stem cells and pharmacological agents to the targeted tissues of the retina, choroid and optic nerve. The invention, in some embodiments thereof, relates to the methods for improving pancreatic insulin secretion, thereof to enhance glucose uptake by PRs and other retinal cells. Additionally or alternatively, the invention relates to restoration of transduction of signaling in cone PRs by ONS induced glutamate release. The methods of the invention, in some embodiments thereof, include priming of the retina choroid and optic nerve thereof to enhance the efficacy of cell transplantation therapy. The methods of the invention, in some embodiments thereof, also include identifying a subject prone to or suffering from a disease or condition associated with reduced OBF. Methods of the invention, in some embodiments thereof, may also include monitoring the subject for prophylactic treatment where the patients are at pre-clinical stage of the disease. The OBF of subjects who had received neuromodulation treatment may also be monitored for re-treatment.The present invention, in some embodiments thereof, relates to a method and / or device for treatment of dysregulated reduced blood (e.g. reduced ocular blood flow) and, more particularly, but not exclusively, to methods and / or devices for treatment retinal, choroidal and optic nerve disorders. Optionally, treatment may include application of an effective amount of ONS ophthalmic nerve stimulation alone and / or in combination with pen-ocular administration of substance Neuropeptides / Platelet Rich Plasma (N / PRP) and / or ascorbic acid as a sympatholytic agent
Owner:MUSALLAM ISMAIL MOHAMMED YOUSIF

Sacrum nerve puncture path simulation planning system and device

The invention provides a sacrum nerve puncture path simulation planning system and device, and relates to puncture operation simulation. The sacrum nerve puncture path simulation planning system comprises an image obtaining module and a path simulation planning module, and the image obtaining module is configured to obtain scanning images of sacrum, sacral foramen and a positioning grid located at a lumbosacral part; and the path simulation planning module is configured to establish a three-dimensional model of the sacrum, the sacral foramen and the positioning grid according to the scanned image, and acquire a virtual puncture path penetrating through the positioning grid to reach a sacrum set position and an intersection point of the positioning grid and the virtual puncture path according to the three-dimensional model. The problems that at present, sacral nerve holes are directly punctured for many times, and pain of patients is large are solved. By acquiring the scanning images of the positioning grid, sacrum and sacral foramen, taking the positioning grid as a positioning reference, reconstructing the three-dimensional model of the sacrum, the sacral foramen and the positioning grid, taking a reference of penetrating through the positioning grid to reach a sacrum set position, and establishing a plurality of virtual puncture paths, a human organ state and an actual puncture process are simulated.
Owner:SHANDONG UNIV QILU HOSPITAL

Vertigo protection mechanism for cranial nerve injury patient

The invention relates to the technical field of nerve vertigo and discloses a cranial nerve injury patient vertigo protection mechanism. The mechanism comprises a shell, wherein an air bag is fixedly connected to the inner side of the shell, a connecting block is fixedly connected to the inner wall of the shell, an electrode column is fixedly connected to the inner wall of the connecting block, and a leather ring is fixedly connected to the outer side of the electrode column; an electric heating wire is fixedly connected to the inner side of the leather ring, a round hole is formed in an inner wall of the connecting block, an electromagnet is fixedly connected to the inner wall of the shell, and a limiting block is elastically connected to the position, close to the outer side of the electromagnet, of the inner wall of the shell. According to the vertigo protection mechanism for the cranial nerve injury patient, through explosion of sodium azide in the leather ring, when the cranial nerve patient is in a standing state, if vertigo occurs, the cranial nerve patient topples over, a head of the cranial nerve patient is prevented from colliding with the ground, damage to the head is avoided, and damage to the cranial nerve patient is relieved; and potential safety hazards in rehabilitation of cranial nerve patients are eliminated.
Owner:JILIN UNIV FIRST HOSPITAL

Mandibular ascending branch inner side drag hook special for maxillofacial surgery

The invention discloses a mandibular ascending branch inner side drag hook special for maxillofacial surgery and relates to the technical field of medical treatment. The mandibular ascending branch inner side drag hook comprises an L-shaped grab handle and an end rod, an angle adjusting mechanism is mounted on one side of the L-shaped grab handle, an extension rod is mounted on one side of the angle adjusting mechanism, a locking nut is connected to one side of the extension rod, a supporting rod is connected to one side of the locking nut, an inner groove is formed in the supporting rod, an adjusting nut is arranged in the inner groove, a connecting screw rod penetrates through the adjusting nut, and an auxiliary lighting mechanism is installed on one side of the connecting screw rod. Themandibular ascending branch inner side drag hook is provided with an end rod, a bent hook and a supporting rod. The arc-shaped structure of the end rod can effectively adapt to the internal conditionof the oral cavity, the hook can hook the lower jaw ascending branch to expose the operation field, the inferior alveolar nerve can be prevented from being damaged, and the integrated structure of the end rod, the hook and the supporting rod can improve the convenience of force application.
Owner:王立山
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