The invention discloses a production process of a formula of a compound 
dendrobium huoshanense extract. The compound 
dendrobium huoshanense extract comprises the following raw materials in percentage by weight: 40-50 percent of 
dendrobium huoshanense, 30-40 percent of 
American ginseng and 15-25 percent of barbary wolfberry. The production process comprises the following steps of: picking the raw materials in a certain weight ratio, removing impurities, cleaning, scattering for cooling, smashing the raw materials except the wolfberry and sieving with a 
sieve of 10-20 meshes; adding 
dendrobium huoshanense and barbary wolfberry into water of which the amount is 10-15 times that of the 
dendrobium huoshanense and barbary wolfberry, boiling in a boiling tank three times respectively, filtering a boiling liquid obtained every time, combining the filtrate, concentrating at negative pressure till thick paste is formed and removing filter residues; adding the 
American ginseng into 
ethanol of which the weight is 10-15 times that of the 
American ginseng and the concentration is 70 percent, boiling three times, filtering the boiling liquid, combining, concentrating at negative pressure till thick paste is formed and recovering 
ethanol; combining the extracts, further concentrating at negative pressure till the density is 1.1*103-1.2*103 kg / m<3>; and 
filling in a sterile state. The invention has the advantages that: reasonable and effective utilization of 
dendrobium huoshanense is realized, the 
dissolution rates of active ingredients of dendrobium huoshanense are increased, and the compound dendrobium huoshanense extract is convenient to take and has a good effect.