The invention discloses a production method of pre-degreasing-bleaching high-speed high-yield all-cotton spunlace non-woven fabric. The method comprises a raw cotton degreasing and bleaching process and a spunlace non-woven fabric production process, wherein the raw cotton degreasing and bleaching process comprises the steps of opening, combing, cake making, degreasing and bleaching, dewatering, wet opening, drying, packaging and the like which are carried out in sequence, and the spunlace non-woven fabric production process adopts degreased and bleached cotton prepared through the raw cottondegreasing and bleaching process for producing the spunlace non-woven fabric, and comprises the procedures of opening and mixing, carding, net forming, spunlace, drying, coiling, slitting and the likewhich are carried out in sequence. The method has the beneficial effects that raw cotton is firstly manufactured into degreased and bleached all-cotton through the degreasing and bleaching process, then the degreased and bleached all-cotton is manufactured into the spunlace non-woven fabric, in the production process, the spunlace non-woven fabric has the advantages of being wide in breadth, highin vehicle speed, high in productivity, few in neps, good in product quality and the like, the labor cost can be effectively reduced, the production efficiency is improved, and the production cost isreduced.