The invention relates to a piezoelectrically-driven spraying direction flexible adjustment device. The piezoelectrically-driven spraying direction flexible adjustment device comprises a spray head installation surface (21), a cantilever deformation zone (22) and an installation supporting zone (23), wherein the spray head installation surface (21) is composed of an elastic sheet (2) and a sheet (3) made of piezoelectric materials, the sheet (3) made of the piezoelectric materials adhere to the surfaces of cantilevers in the cantilever deformation zone (22), the installation supporting zone (23) is fixed to a required position during operation, voltage is exerted on the portion between the two electrodes of each sheet (3) made of the piezoelectric materials, bending deformation happens to the cantilever deformation zone (22), the normal direction of the spray head installation surface (21) is changed under the combined action of the deformation of all the cantilevers, a spray head (1) is fixed to the spray head installation surface, the spraying direction of the spray head is the same as the normal direction of the spray head installation surface (21), the spraying direction can be controlled by adjusting the deformation of all the cantilevers, and thus the direction of the spray head (1) is changed. The piezoelectrically-driven spraying direction flexible adjustment device has the advantages that the response frequency is high, the structure is simple, machining is convenient, digital control is facilitated, and the control precision is high.