The invention relates to a mother-infant wireless observation system, which is a wearable wireless body sensor network, and comprises wearable body sensor network clothes, a mobile gateway for collecting and processing data and a human-machine interface which can be seen by a computer and a user. Four wireless human-body sensor nodes which measure the health conditions of a mother and a fetus in a real-time manner and record data in a real-time manner are arranged on the body sensor network clothes; and each wireless human-body sensor node comprises an antenna, a transceiver, a microprocessor, a built-in sensor and a battery pack. The mother-infant wireless observation system has the advantages of software and hardware design with low cost and low energy consumption, can be popularized widely and used for a long time, process and analyze the data transmitted back from the human-body sensor nodes and extract important information, and judge the pregnancy complications at the earliest possible time; and by adopting the anti-interference design, radio interference among the sensor nodes and between the sensors and environment are reduced, and the safety of important medical data can be ensured.