The invention discloses an animal bone and meat seasoning and a preparation method thereof. The bone and meat seasoning comprises the following raw materials in percentage by weight: 95-100% of bone and meat, 0-4% of bone soup seasoning, 0-1% of spices, 0-1% of seasoning oil and 0-4% of vegetables, wherein the sum of the weight percentages of all the components is 100%. The preparation method of the animal bone and meat seasoning comprises the following steps: S1, raw material acceptance and pretreatment; S2, crushing to obtain bone and meat blocks and residues; S3, water addition into the bone and meat blocks and residues, boiling with water, and draining; S4, freezing; S5, compression molding; and S6, inspecting, packaging and warehousing to obtain the animal bone and meat seasoning. Theanimal bone and meat seasoning provided by the invention is rich in nutrients, convenient to use, wide in use range, outstanding in bone and meat feeling and good in palatability.