The invention discloses a penicillin bottle dispensing machine. The penicillin bottle dispensing machine comprises a swinging driving motor, a dial, a lifting disc, a rotating framework, a dial longitudinal and transverse moving driver, a dial lifting mechanism, a transfusion bag tray, a retaining overturn plate driving mechanism, a penicillin bottle clamping frame stacking mechanism, a penicillinbottle clamping frame guiding plate, a penicillin bottle clamping frame driving and reversing mechanism, a penicillin bottle clamping frame tray, a penicillin bottle clamping frame tilting machine driver, an enclosure, supporting legs, a penicillin bottle clamping frame, a needle tube frame, a transition bridge and a rack, wherein the penicillin bottle clamping frame driving and reversing mechanism is connected with the penicillin bottle clamping frame guiding plate; the penicillin bottle clamping frame guiding plate can rotate around an upper shaft; the penicillin bottle clamping frame stacking mechanism is arranged at the right side of the penicillin bottle clamping frame driving and reversing mechanism; the needle tube frame is located at the right side of the rack. According to the penicillin bottle dispensing machine disclosed by the invention, the structural design is reasonable, multiple groups can work at the same time, and the automation degree is high; various operation canbe carried out, and great convenience is provided for dispensing work of penicillin bottles.