34 results about "DISORDER EYE" patented technology

The invention discloses a pair of intelligent eyesight monitoring and eye disease prediction glasses, and aims to solve the problems that most of existing eye health monitoring devices are used for regular inspection, cannot monitor and predict the eye health condition in real time and are difficult to take intervention measures in time, the glasses comprise glasses legs and a glasses main body, and the glasses main body is provided with an inner side facing a wearer; the glasses body further comprises a miniature camera, an optical sensor, a master control system and a battery system. The miniature camera is connected with the main control system through an application-specific integrated circuit, and the miniature camera is installed on the inner side of the glasses body facing the eyes of a wearer and used for shooting eye images of the wearer in real time and capturing the pupil size, eyeball movement and sight line direction of the wearer; the optical sensor is connected with the main control system and is used for detecting the ambient light intensity and color and adjusting the brightness of the lenses of the glasses main body; the eye health condition of the teenagers can be monitored and predicted in real time, and accurate health data support is provided for parents, teachers and ophthalmologists.

The present invention relates to an eye movement function quantitative evaluation system based on an eye tracker, which can realize automatic quantitative evaluation of three eye functions: fixation, saccade and smooth pursuit, and provide support for eye disease diagnosis and eye rehabilitation effect evaluation. The system includes an eye tracker, an evaluation interface generation module, a data processing module, a motor function evaluation module and an evaluation result display interface. The computer processes the acquired eye movement data, calculates the eye movement data characteristics, designs the eye movement function quantitative rating index, and automatically gives the quantitative rating result, so that the diagnosis result is more accurate, intuitive and convenient, reduces the workload of doctors, provides doctors with more accurate eye movement diagnosis information, and helps doctors understand the patient's eye movement function status, so as to better diagnose and treat. Starting from the clinical needs of ophthalmology, this system realizes automatic quantitative evaluation and grading of eye movement function, provides reference for eye disease diagnosis and eye rehabilitation effect evaluation, and is of great significance.

The present invention provides a method and apparatus for identifying thyroid-related ophthalmopathy based on eye CT images. The method includes: obtaining a plurality of slice images of an eye image; screening the plurality of slice images to obtain target CT slice images, where the target CT slice images are CT slice images that can be used to judge thyroid-related ophthalmopathy; segmenting each of the target CT slice images to extract contour location information of the eyeball and the orbit in each of the target CT slice images; and obtaining an identification result of thyroid-related ophthalmopathy based on the contour location information of the eyeball and the orbit. In the embodiments of the present invention, by automatically screening and identifying a plurality of slice images, not only the number of annotations is reduced, the development cost is saved, but also the diagnosis efficiency of thyroid-related ophthalmopathy is improved.

The present invention belongs to the technical field of polymer compounds, and specifically relates to the use of amphiphilic cationic modified mPEG-PCL nanoparticles in the preparation of drugs for treating retinal diseases. The technical problem to be solved by the present invention is the lack of nanomedicines for the treatment of retinal diseases. The technical solution of the present invention is the use of amphiphilic cationic modified mPEG-PCL nanoparticles in the preparation of drugs for treating eye diseases. The nanoparticles of the present invention have low cytotoxicity; can effectively inhibit the development of choroidal neovascularization; and can also be used as carriers for other eye disease-related drugs, enabling combined drug use and the treatment of various eye diseases.

The invention discloses a retina image processing method, system and device for ophthalmic diseases, and belongs to the technical field of image analysis, and the method comprises the steps: carrying out the quality inspection and preprocessing of an uploaded retina image, and obtaining a to-be-recognized retina image; lesion positioning and refraction problem recognition are carried out on the to-be-recognized retina image, and a lesion thermodynamic diagram and an eye disease recognition result are output; based on a preset ophthalmic disease database, performing confidence calculation on the eye disease recognition result to obtain a corresponding treatment suggestion; and according to the focus thermodynamic diagram, the eye disease identification result and the treatment suggestion, generating a diagnosis and treatment sheet of the retina image. Therefore, by implementing the method and the device, the problems that various retinal diseases and refraction problems cannot be quickly and accurately identified from the provided retinal image and effective clinical diagnosis opinions cannot be provided for the identified ophthalmic diseases in the prior art can be solved.

The present disclosure provides an ophthalmic formulation comprising: one or more pharmaceutically acceptable excipients; a pharmaceutically active compound capable of reducing the amount or deleterious effects of autoantibodies on the ocular surface, such as IgG; in particular, the present disclosure provides an ophthalmic formulation wherein the pharmaceutically active compound is capable of treating a clinical condition selected from the group consisting of inflammatory, infectious and immunological ocular surface or intraocular diseases that can cause symptoms of ocular discomfort, keratitis, dry eye disease, formation of symblepharon, shortening of the anterior chamber depth, lid margin / conjunctival keratinization, subconjunctival fibrosis, retinal gliosis and glaucoma.

Provided herein are methods of treating eye disorders by administering an anti-VEGF antibody and / or conjugate to a subject having an eye disorder. The anti-VEGF antibody of the present disclosure may be an anti-VEGF antibody conjugate that includes a polymeric moiety that extends the half-life / effectiveness / properties of the antibody when administered to a subject. A method of the present disclosure includes administering one or more doses of an anti-VEGF antibody conjugate to a subject (e.g., human or other mammalian patient) in need of treating an eye disorder, where the anti-VEGF antibody conjugate may be administered less frequently than a standard anti-VEGF therapy to treat the eye disorder.

The invention relates to an eye disease and nerve disease integrated diagnosis and treatment system based on visual signal perception, and belongs to the technical field of visual function detection and diagnosis and treatment assistance. The method comprises the following steps: dynamically generating a black and white checkerboard stimulation signal through a visual stimulation generation unit, and triggering an eye and a nervous system to generate an original evoked potential signal; the signal acquisition and transmission unit acquires and sends the signal through an electrode plate and a wireless transmission module; the signal processing and judging unit is used for carrying out superposition processing on the signals, extracting effective waveforms and automatically executing spatial frequency threshold search to determine a minimum checkerboard; and the diagnosis and treatment scheme output unit generates a stimulation program based on the minimum checkerboard and dynamically generates a personalized diagnosis and treatment report. The full-process automation from stimulation generation, signal processing to scheme output is realized, the accuracy of threshold judgment and the personalization of the stimulation scheme are improved, and efficient and reliable technical support is provided for auxiliary diagnosis and curative effect evaluation of eye diseases and nerve diseases.

The present disclosure provides a composition and method for preventing or treating eye diseases. Specifically, a method for preparing mesenchymal stem cell conditioned medium is provided, which includes isolating mesenchymal stem cells from an individual, maintaining the mesenchymal stem cells in a mesenchymal stem cell maintenance medium, collecting the mesenchymal stem cells at passages 2 to 5, culturing the mesenchymal stem cells for several hours in a medium supplemented with fetal bovine serum and a mesenchymal stem cell medium adjuvant to obtain the mesenchymal stem cell conditioned medium, collecting the conditioned medium, and filtering it after centrifugation. The present disclosure also provides a method for preventing or treating an ocular epithelial tissue disorder such as dry eye disease, which includes administering the conditioned medium to the eye of an individual. The present disclosure further provides a pharmaceutical composition comprising the conditioned medium.

The invention relates to the technical field of intraocular lenses, in particular to a multi-focus intraocular lens dynamic tuning system and method for complex eye diseases. The invention relates to a multi-focus intraocular lens dynamic tuning system which integrates multiple functions of eyeball parameter receiving, tuning instruction generation, micro electrode array adjustment, driving loop control, electric control zoom lens dynamic focusing, wireless energy supply and monitoring, eyeball movement monitoring, safety control, data processing and display and the like. The system monitors eyeball movement in real time and dynamically adjusts the shape and the thickness of the crystal, so that accurate focusing is realized, and the visual quality and the adjusting performance are remarkably improved. Meanwhile, energy efficiency is improved through wireless energy supply, and safe operation is ensured through intelligent monitoring. The system breaks through the limitation of the prior art, creates a new intelligent intraocular lens normal form, provides an efficient, safe and intelligent solution for complex eye disease treatment, and has wide application prospects and great clinical value.

The present invention discloses a manufacturing method of an artificial cornea for one-time implantation, belonging to the technical field of in-vivo prosthesis implantation. It solves at least the problems existing in the prior art, such as the need for donor corneas, multiple surgeries, large trauma and inapplicability to patients with severe eye diseases. The manufacturing method includes: manufacturing a lens column, which sequentially includes a first threaded section, a second threaded section, an optical axis section, a rear disc and a rear convex section from the front end to the rear end; manufacturing a stent, which includes a stent body and a connecting ring; the stent body is made of metal and is formed by stamping; manufacturing a cosmetic disc, the material of the cosmetic disc is the same as that of the lens column and is formed by injection molding, the cosmetic disc has a central connection hole, and the inner wall of the central connection hole has an internal thread that is screwed with the first threaded section; assembling the lens column, the stent and the cosmetic disc, specifically including: snapping the connecting ring into the central mounting hole of the stent body from top to bottom, and making the stent body snap into the annular limiting groove of the connecting ring to complete the assembly of the stent.

The invention belongs to the technical field of visual function inspection devices, and relates to an adjusting amplitude inspection device based on a turnover mirror and a using method thereof.The adjusting amplitude inspection device comprises a fixing support, the turnover mirror and a sighting mark structure, the turnover mirror and the sighting mark structure are arranged at the two ends of the fixing support, and the sighting mark structure is slidably arranged on the fixing support; the sighting mark structure is arranged on the fixing support to be close to or away from the overturning mirror, and a length scale arranged in the sliding direction of the sighting mark structure is arranged on the fixing support. Accuracy and reliability of adjustment amplitude examination are remarkably improved, the method is suitable for groups such as children and patients with special refraction, the clinical operation process is simplified, the application range is expanded, eye diseases such as asthenopia and myopia progress are effectively diagnosed through standardized stimulation and dynamic adjustment, and progress of eye vision light practice is promoted.

The invention discloses an optic nerve image segmentation and recognition method and system based on an AI model. Semantic segmentation processing is carried out on an optic nerve image of a patient object by adopting an image processing technology based on deep learning. Firstly, contrast enhancement, Gaussian filtering and image size adjustment are performed on an optic nerve image of a patient object, so that image quality is improved, and optic nerve structural features are highlighted. And then, semantic feature extraction and pixel-level classification are performed on the preprocessed optic nerve image by using a neural network model, so that accurate segmentation and recognition of the optic nerve image are realized. Particularly, in the Gaussian filtering process of the optic nerve image, a mode of dynamically adjusting the standard deviation of the Gaussian filter is adopted to cope with the quality difference of different images, so that the noise reduction processing effect of the image is optimized. Therefore, the accuracy of optic nerve image segmentation can be effectively improved, the lesion area of optic nerves can be identified, and more accurate auxiliary information can be provided for clinical diagnosis of eye disease patients.

1. The name of the product of this design: Eye therapy device for the elderly. 2. Purpose of the product with this appearance design: The eye therapy device for the elderly has various functions. It can massage the eyes, relieve fatigue, promote blood circulation and improve vision. It can also regulate eye muscles and prevent eye diseases. It is easy to use and can help the elderly protect their eye health and improve their quality of life. 3. The design key point of this appearance design product lies in the shape. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The invention relates to an eye-protecting health-care traditional Chinese medicine composition, which is used for relieving eye fatigue, improving vision and preventing or assisting in treating retinopathy and xerophthalmia, and has the comprehensive effects of clearing liver and improving vision, nourishing blood and liver, promoting blood circulation to remove meridian obstruction, nourishing yin and moistening dryness. All the components have a synergistic effect in efficacy, and the effects of eye protection and health care are achieved by regulating the liver function, enhancing eye blood circulation, improving cell metabolism and enhancing the immune function. According to the traditional Chinese medicine composition disclosed by the invention, various medicinal materials have a good synergistic effect, and the multiple effects of clearing liver and improving vision, nourishing blood and liver, promoting blood circulation to remove meridian obstruction, nourishing yin and moistening dryness are comprehensively exerted by regulating liver and kidney functions, improving eye microcirculation, enhancing cell metabolism capability and improving immune level; therefore, eye fatigue is effectively relieved, eyesight is improved, common eye diseases such as retinopathy and xerophthalmia are prevented or treated in an auxiliary manner, and the eye cream is suitable for sub-health people and daily health care requirements.

The invention relates to the field of medicine, in particular to universal antiviral eyedrops and a preparation method thereof. The antiviral eyedrop comprises 5-19% by mass of sodium chloride and 95-81% by mass of pure water, and is a special advanced physiological sodium chloride water-soluble solution prepared by a specific method. The mechanism for preparing the antiviral eyedrops from sodium chloride is as follows: firstly, the content of sodium chloride in a sodium chloride water-soluble liquid is determined to be greater than or equal to 5% for the first time, and the eyedrops have a universal specific medicinal function of resisting eye disease viruses; and secondly, the tolerable safety limit value of the eyes of people to the sodium chloride content of the sodium chloride water-soluble liquid can reach 19% threshold value for the first time. According to the invention, the sodium chloride content ratio threshold value of the 5-19% sodium chloride water-soluble liquid with unified effectiveness and safety is set as a basic technical formula and standard for preparing the novel antiviral eye drops from sodium chloride. Meanwhile, the antiviral eyedrops are designed to be light and thick so as to be suitable for patients in primary clinical treatment.

Provided herein is a method for treating, preventing, or ameliorating one or more symptoms of an inflammatory eye disease, disorder, or condition with a JAK inhibitor, for example, a tricyclic JAK inhibitor of Formula (I). Also provided herein is a stable ophthalmic composition comprising a JAK inhibitor, for example, a tricyclic JAK inhibitor of Formula (I); and a buffering agent, a mucoadhesive agent, a preservative, a solubilizer, a tonicity agent, or water, or a mixture thereof.

The utility model discloses a pair of lesion visual simulation glasses, which comprises a main frame connected with glasses legs or a head-mounted structure; the support is connected with the main frame, and an inserting groove is formed in the support; the vision simulation module is detachably inserted into the slot, and a lesion simulation layer is arranged on the vision simulation module. According to the lesion visual simulation glasses, the lesion simulation layer is arranged on the vision simulation module and used for simulating the visual effect of eye lesion when a normal person wears the glasses, and therefore products suitable for the old can be developed conveniently. The bracket is provided with the slot, and the vision simulation module is detachably inserted into the slot, so that the vision simulation module provided with different lesion simulation layers can be replaced, the vision simulation module is used for simulating a visual effect without eye diseases, and the simulation cost can be reduced.

The utility model provides VR equipment and a VR glasses light machine, and the VR glasses light machine comprises a frame. The frame is provided with a display screen and photochromic glass for light rays emitted by the display screen to pass through; and a light path folding film is attached to the incident surface and / or the emergent surface of the photochromic glass. The photochromic glass is used for adjusting the light intensity, so that the light intensity is kept in a proper range, and the probability of eye diseases caused by too strong light is reduced.

The utility model discloses a glasses frame capable of adjusting interpupillary distance, which consists of a left sheet frame, a right sheet frame, an upper eyebrow, a left glasses leg and a right glasses leg, the left glasses leg and the right glasses leg are respectively arranged on the left side and the right side of the upper eyebrow, a buckle is arranged on the upper eyebrow corresponding to a nose bridge, and a support rod with a scale is fixed on the buckle. And the left and right lens frames for mounting the lenses are respectively mounted on the left and right sides of the supporting rod in a relative sliding manner. The utility model also discloses a pair of glasses using the glasses frame. The pair of eyeglasses has the advantages of few components, simpler structure and easier assembly, can complete the interpupillary distance adjustment by directly pulling the lens frame to slide on the support rod and stopping pulling when reaching a proper interpupillary distance, is very convenient, rapid and accurate in adjustment operation, is suitable for network sales and purchase, is also suitable for correcting eye diseases such as strabismus with asymmetric left and right interpupillary distances, and is suitable for popularization and application. The auxiliary treatment effect is realized.

The invention relates to a periorbital smearing type oculentum for treating eye diseases and a preparation method of the periorbital smearing type oculentum, and belongs to the technical field of eye treatment. Comprising 10-15 parts of a coptis chinensis extract, 5-10 parts of a scutellaria baicalensis extract, 20-30 parts of a wild chrysanthemum flower extract, 8-12 parts of a selfheal extract, 8-12 parts of a plantain seed extract, 8-12 parts of a safflower extract, 80-100 parts of distilled water, 15-20 parts of an antioxidant, 8-12 parts of a heat-clearing and detoxifying agent, 2-5 parts of a cooling and pain-relieving agent and 14-20 parts of a mixing agent. The antioxidant is prepared from 5 to 10 parts of radix scutellariae and 10 to 15 parts of radix angelicae sinensis. The heat-clearing and detoxifying agent comprises 5-10 parts of bear gall powder and 5-8 parts of selfheal. The cooling and pain relieving agent comprises 2-5 parts of borneol and 2-5 parts of menthol. The mixing agent comprises 10-15 parts of glycerol and 4-6 parts of sodium carboxymethyl cellulose. The essential oil further comprises 2-4 parts of tea tree essential oil and 1-3 parts of abelmoschus manihot essential oil. The traditional Chinese medicine composition can effectively improve eye symptoms, increase tear secretion amount and relieve corneal injury.

This invention relates to a nanoparticle, its preparation method and application, and a drug comprising the nanoparticle for treating eye diseases and its preparation method. The nanoparticle comprises ribonucleic acid (RNA) and thiols, wherein the RNA comprises double-stranded RNA and RNA aptamers.

The invention discloses an on-site operation and maintenance work safety guidance device based on AI glasses, which comprises a safety helmet main body and an AI single lens, the safety helmet main body comprises a brim, a fixed box with an opening at the bottom is fixedly arranged below the brim, and the middle part of the top of the fixed box is provided with a hidden box protruding upwards. A fixed box and a hidden box located above the fixed box are arranged, a belt transmission mechanism is installed in the fixed box, a conveying belt on the belt transmission mechanism passes through the top in the hidden box and is connected with a door-shaped frame through a hanging mechanism, an AI single lens is arranged in the door-shaped frame, and the conveying belt can drive the door-shaped frame to enter and exit from the hidden box through the hanging mechanism during operation. Meanwhile, the door-shaped frame can be driven to move to the position in front of the left eye or the right eye of an executor, so that the left eye and the right eye can watch the AI single lens in turn according to needs, eye fatigue can be effectively relieved, the risk of eye diseases can be reduced, the hidden box has the function of hiding and protecting the AI single lens, and the AI single lens can be effectively prevented from being polluted, collided and damaged.

The invention discloses eye drops for treating eye diseases and a preparation method of the eye drops, and relates to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine extracting solution is an extracting solution of mother-of-pearl, flos eriocauli, herba equiseti hiemalis, bat dung, flos buddlejae, semen celosiae and borneol. The invention aims to provide the eye drops for treating the eye diseases and the preparation method thereof, the eye drops have good prevention and treatment effects on various eye diseases, and the problems that in the prior art, many impurity residues exist, effective substances are difficult to permeate, and the use effect is poor are solved.

A device for treating eye disorders, particularly disorders of the internal tissues of the eye, comprises a mask and a plurality of light-emitting diodes (LEDs) arranged on the inner surface of the mask. The plurality of LEDs includes a matrix of at least one LED arranged in a region of the inner surface of the mask that is adapted to face the user's eyeball area when in use, and is configured to emit electromagnetic radiation adapted to stimulate the cellular function of retinal cells.

The invention provides a vehicle-mounted head-up display control method, system and device. The method comprises the steps that the final visual focusing time and the final focusing stabilization time of a driver are collected in real time; evaluating the final visual focusing time and the final focusing stable time based on a preset visual focusing time range and a preset focusing stable time range to obtain a visual focusing time evaluation result and a focusing stable time evaluation result; obtaining a final evaluation result based on the visual focusing time evaluation result and the focusing stabilization time evaluation result; and adjusting the display parameters of the vehicle-mounted head-up display in real time based on the final evaluation result. According to the method provided by the invention, the technical problems that in the vehicle driving process, part of eye disease patients such as presbyopia patients are difficult to quickly and clearly identify near vehicle-mounted head-up display contents due to slow vision focusing speed and inflexible focus switching, the driving experience is poor, and the driving safety is influenced are effectively solved.

In the present invention azidation is used to render a molecule photoactivable and to influence its binding to its cognate specific binding partner in the eye. Thus, the invention relates to a compound for use in a method of treating a subject with an ocular disease said compound comprising - a conjugated electron system - an active agent moiety, - an azide (N3) moiety comprising an azido group, wherein the π electrons of the azido group extend the conjugated electron system to form an extended conjugated electron system, whereby the active agent moiety can be bound to the binding site of the biological target, and the azide moiety can be photoactivated by the light entering via the optical system of the eye, whereby the engineered molecule becomes linked to the biological target via a covalent bond, whereby the compound modulates the said biological target in the eye to provide an improved treatment for said subject.

The invention belongs to the field of animal model construction, and particularly relates to a construction method and application of an early embryonic development cataract eye disease animal model. The invention finds that acute exposure of N-(1, 3-dimethylbutyl)-N '-phenyl-p-phenylenediamine (6PPD) and polystyrene microspheres (PS) in an embryonic development stage can cause eye dysplasia and visual dysfunction in a zebra fish larva stage, and the zebra fish has typical lens opacification-like cataract pathological characteristics; meanwhile, the phenomena of phototactic behavior inhibition, eye cell death increase and the like occur. The 6PPD / PS treatment interferes with visual perception and phototransduction pathways, significantly affects photoreceptor outer segment, ferroptosis, endocytosis, retinoic acid metabolism and other pathways, and can enhance the activation of ferroptosis regulation genes by enhancing oxidative stress and mitochondrial dependent apoptosis of eye tissues, thereby aggravating the cataract process. The invention finds that cataract can be generated through the 6PPD / PS effect in the development process of freshwater fish vertebrates for the first time, and provides model support for research on pathogenesis and intervention strategies of the freshwater fish vertebrates.

The invention relates to the technical field of eye care liquid, and particularly discloses eye care liquid and a preparation method thereof. The eye health-care liquid is prepared from the following raw materials in parts by weight through biological fermentation: 1-6 parts of chrysanthemum, 1-6 parts of semen cassiae, 1-5 parts of ginseng, 1-6 parts of radix zanthoxyli, 1-5 parts of cinnamon, 1-10 parts of red dates, 1-5 parts of cassia twig, 1-6 parts of safflower, 1-8 parts of white poria, 1-4 parts of radix saposhnikoviae, 1-8 parts of angelica sinensis, 1-5 parts of ligusticum wallichii and 1-6 parts of radix paeoniae alba. The traditional Chinese medicine composition has the beneficial effects that the composition is high in synergism, the compatibility of monarch, minister, assistant and guide is rigorous aiming at the core pathogenesis of eye diseases such as deficiency of liver and kidney, deficiency of qi and blood and blood stasis and wind heat, and multi-target comprehensive conditioning is realized. A fermentation process under specific conditions is adopted, compared with traditional water decoction or alcohol extraction, the active ingredients are richer, the molecular weight is smaller, transdermal absorption is easier, the bioavailability is remarkably improved, and damage of high temperature to heat sensitive ingredients is avoided.