12 results about "DISORDER EYE" patented technology

The present disclosure provides an ophthalmic formulation comprising: one or more pharmaceutically acceptable excipients; a pharmaceutically active compound capable of reducing the amount or deleterious effects of autoantibodies on the ocular surface, such as IgG; in particular, the present disclosure provides an ophthalmic formulation wherein the pharmaceutically active compound is capable of treating a clinical condition selected from the group consisting of inflammatory, infectious and immunological ocular surface or intraocular diseases that can cause symptoms of ocular discomfort, keratitis, dry eye disease, formation of symblepharon, shortening of the anterior chamber depth, lid margin / conjunctival keratinization, subconjunctival fibrosis, retinal gliosis and glaucoma.

Provided herein are methods of treating eye disorders by administering an anti-VEGF antibody and / or conjugate to a subject having an eye disorder. The anti-VEGF antibody of the present disclosure may be an anti-VEGF antibody conjugate that includes a polymeric moiety that extends the half-life / effectiveness / properties of the antibody when administered to a subject. A method of the present disclosure includes administering one or more doses of an anti-VEGF antibody conjugate to a subject (e.g., human or other mammalian patient) in need of treating an eye disorder, where the anti-VEGF antibody conjugate may be administered less frequently than a standard anti-VEGF therapy to treat the eye disorder.

The invention belongs to the technical field of visual function inspection devices, and relates to an adjusting amplitude inspection device based on a turnover mirror and a using method thereof.The adjusting amplitude inspection device comprises a fixing support, the turnover mirror and a sighting mark structure, the turnover mirror and the sighting mark structure are arranged at the two ends of the fixing support, and the sighting mark structure is slidably arranged on the fixing support; the sighting mark structure is arranged on the fixing support to be close to or away from the overturning mirror, and a length scale arranged in the sliding direction of the sighting mark structure is arranged on the fixing support. Accuracy and reliability of adjustment amplitude examination are remarkably improved, the method is suitable for groups such as children and patients with special refraction, the clinical operation process is simplified, the application range is expanded, eye diseases such as asthenopia and myopia progress are effectively diagnosed through standardized stimulation and dynamic adjustment, and progress of eye vision light practice is promoted.

The invention relates to an eye-protecting health-care traditional Chinese medicine composition, which is used for relieving eye fatigue, improving vision and preventing or assisting in treating retinopathy and xerophthalmia, and has the comprehensive effects of clearing liver and improving vision, nourishing blood and liver, promoting blood circulation to remove meridian obstruction, nourishing yin and moistening dryness. All the components have a synergistic effect in efficacy, and the effects of eye protection and health care are achieved by regulating the liver function, enhancing eye blood circulation, improving cell metabolism and enhancing the immune function. According to the traditional Chinese medicine composition disclosed by the invention, various medicinal materials have a good synergistic effect, and the multiple effects of clearing liver and improving vision, nourishing blood and liver, promoting blood circulation to remove meridian obstruction, nourishing yin and moistening dryness are comprehensively exerted by regulating liver and kidney functions, improving eye microcirculation, enhancing cell metabolism capability and improving immune level; therefore, eye fatigue is effectively relieved, eyesight is improved, common eye diseases such as retinopathy and xerophthalmia are prevented or treated in an auxiliary manner, and the eye cream is suitable for sub-health people and daily health care requirements.

Provided herein is a method for treating, preventing, or ameliorating one or more symptoms of an inflammatory eye disease, disorder, or condition with a JAK inhibitor, for example, a tricyclic JAK inhibitor of Formula (I). Also provided herein is a stable ophthalmic composition comprising a JAK inhibitor, for example, a tricyclic JAK inhibitor of Formula (I); and a buffering agent, a mucoadhesive agent, a preservative, a solubilizer, a tonicity agent, or water, or a mixture thereof.

The utility model discloses a pair of lesion visual simulation glasses, which comprises a main frame connected with glasses legs or a head-mounted structure; the support is connected with the main frame, and an inserting groove is formed in the support; the vision simulation module is detachably inserted into the slot, and a lesion simulation layer is arranged on the vision simulation module. According to the lesion visual simulation glasses, the lesion simulation layer is arranged on the vision simulation module and used for simulating the visual effect of eye lesion when a normal person wears the glasses, and therefore products suitable for the old can be developed conveniently. The bracket is provided with the slot, and the vision simulation module is detachably inserted into the slot, so that the vision simulation module provided with different lesion simulation layers can be replaced, the vision simulation module is used for simulating a visual effect without eye diseases, and the simulation cost can be reduced.

The invention discloses an on-site operation and maintenance work safety guidance device based on AI glasses, which comprises a safety helmet main body and an AI single lens, the safety helmet main body comprises a brim, a fixed box with an opening at the bottom is fixedly arranged below the brim, and the middle part of the top of the fixed box is provided with a hidden box protruding upwards. A fixed box and a hidden box located above the fixed box are arranged, a belt transmission mechanism is installed in the fixed box, a conveying belt on the belt transmission mechanism passes through the top in the hidden box and is connected with a door-shaped frame through a hanging mechanism, an AI single lens is arranged in the door-shaped frame, and the conveying belt can drive the door-shaped frame to enter and exit from the hidden box through the hanging mechanism during operation. Meanwhile, the door-shaped frame can be driven to move to the position in front of the left eye or the right eye of an executor, so that the left eye and the right eye can watch the AI single lens in turn according to needs, eye fatigue can be effectively relieved, the risk of eye diseases can be reduced, the hidden box has the function of hiding and protecting the AI single lens, and the AI single lens can be effectively prevented from being polluted, collided and damaged.

A device for treating eye disorders, particularly disorders of the internal tissues of the eye, comprises a mask and a plurality of light-emitting diodes (LEDs) arranged on the inner surface of the mask. The plurality of LEDs includes a matrix of at least one LED arranged in a region of the inner surface of the mask that is adapted to face the user's eyeball area when in use, and is configured to emit electromagnetic radiation adapted to stimulate the cellular function of retinal cells.

The invention belongs to the field of animal model construction, and particularly relates to a construction method and application of an early embryonic development cataract eye disease animal model. The invention finds that acute exposure of N-(1, 3-dimethylbutyl)-N '-phenyl-p-phenylenediamine (6PPD) and polystyrene microspheres (PS) in an embryonic development stage can cause eye dysplasia and visual dysfunction in a zebra fish larva stage, and the zebra fish has typical lens opacification-like cataract pathological characteristics; meanwhile, the phenomena of phototactic behavior inhibition, eye cell death increase and the like occur. The 6PPD / PS treatment interferes with visual perception and phototransduction pathways, significantly affects photoreceptor outer segment, ferroptosis, endocytosis, retinoic acid metabolism and other pathways, and can enhance the activation of ferroptosis regulation genes by enhancing oxidative stress and mitochondrial dependent apoptosis of eye tissues, thereby aggravating the cataract process. The invention finds that cataract can be generated through the 6PPD / PS effect in the development process of freshwater fish vertebrates for the first time, and provides model support for research on pathogenesis and intervention strategies of the freshwater fish vertebrates.

The invention relates to the technical field of eye care liquid, and particularly discloses eye care liquid and a preparation method thereof. The eye health-care liquid is prepared from the following raw materials in parts by weight through biological fermentation: 1-6 parts of chrysanthemum, 1-6 parts of semen cassiae, 1-5 parts of ginseng, 1-6 parts of radix zanthoxyli, 1-5 parts of cinnamon, 1-10 parts of red dates, 1-5 parts of cassia twig, 1-6 parts of safflower, 1-8 parts of white poria, 1-4 parts of radix saposhnikoviae, 1-8 parts of angelica sinensis, 1-5 parts of ligusticum wallichii and 1-6 parts of radix paeoniae alba. The traditional Chinese medicine composition has the beneficial effects that the composition is high in synergism, the compatibility of monarch, minister, assistant and guide is rigorous aiming at the core pathogenesis of eye diseases such as deficiency of liver and kidney, deficiency of qi and blood and blood stasis and wind heat, and multi-target comprehensive conditioning is realized. A fermentation process under specific conditions is adopted, compared with traditional water decoction or alcohol extraction, the active ingredients are richer, the molecular weight is smaller, transdermal absorption is easier, the bioavailability is remarkably improved, and damage of high temperature to heat sensitive ingredients is avoided.

The application discloses a compound for eye disease repair and a preparation method of the compound by aging extraction, which is synthesized by extracting effective components of Senecio scandens Buch, astaxanthin, Artemisia capillaris Thunb, Gardenia, Ceti, Cassia seed, and has good therapeutic effect on eye diseases such as myopia, pseudomyopia, cataract, glaucoma, chloasma and the like. By taking the extract, intraocular pressure, optic nerve and intraocular pressure tube are gradually improved, so that the eye axis refraction is basically recovered, and the purpose of basic cure is achieved. The extract is obtained by supercritical extraction of pure plants and traditional Chinese medicines, and the compound Tianmocai compound of Senecio scandens Buch is obtained by using three reaction kettles to induce aging technology, the compound is safe and has no side effect, and is an innovative modern new Chinese medicine technical product.

The embodiment of the invention relates to nanoparticles, a preparation method and application thereof, a medicine comprising the nanoparticles and used for treating eye diseases and a preparation method of the medicine. The nanoparticles comprise ribonucleic acid and thiol, and the ribonucleic acid comprises double-stranded ribonucleic acid and a ribonucleic acid aptamer.