40 results about "Micro spectroscopy" patented technology

Early dental caries detection is carried out by a method that combines optical coherence tomography (OCT) and Raman spectroscopy to provide morphological information and biochemical specificity for detecting and characterizing incipient carious lesions found in extracted human teeth. OCT imaging of tooth samples demonstrated increased light back-scattering intensity at sites of carious lesions as compared to the sound enamel. Raman microspectroscopy and fibre-optic based Raman spectroscopy are used to characterize the caries further by detecting demineralization-induced alterations of enamel crystallite morphology and / or orientation. OCT imaging is useful for screening carious sites and determining lesion depth, with Raman spectroscopy providing biochemical confirmation of caries. The combination is incorporated into a common probe operable without movement to scan the tooth surface and to provide an output for the dentist.

The invention relates to scanning pulsed laser systems for optical imaging. Coherent dual scanning laser systems (CDSL) are disclosed and some applications thereof. Various alternatives for implementation are illustrated, including highly integrated configurations. In at least one embodiment a coherent dual scanning laser system (CDSL) includes two passively modelocked fiber oscillators. The oscillators are configured to operate at slightly different repetition rates, such that a difference δfr in repetition rates is small compared to the values fr1 and fr2 of the repetition rates of the oscillators. The CDSL system also includes a non-linear frequency conversion section optically connected to each oscillator. The section includes a non-linear optical element generating a frequency converted spectral output having a spectral bandwidth and a frequency comb comprising harmonics of the oscillator repetition rates. A CDSL may be arranged in an imaging system for one or more of optical imaging, microscopy, micro-spectroscopy and / or THz imaging.

The invention belongs to the micro-spectrum imaging technical field and relates to a differential confocal raman spectral test method. The method integrates the technical characteristics of the differential confocal detection method and the raman spectral detection method, forms a test method capable of realizing sample microarea spectral detection, precisely catches focus positions of excitationlight beams through the differential confocal technology, detects raman spectra of corresponding positions, simultaneously adopts a designed pupil filter, sharpens Airy disc major lobes of a differential confocal raman spectral system, improves the microarea raman spectral detectability and precisely acquires microarea space spectrum information which comprises spectral information and position information of microarea samples. The method obviously improves the microarea spectral detectability of a confocal raman spectromicroscope, has absolute tracking zero points and bipolar tracking characteristics, realizes absolute measurement of physical dimension, can be widely applied in the technical fields such as biomedicine, life sciences, biophysics, biochemistry, industrial precision detection and so on to perform high-precision detection of geometric positions and spectral characteristics of microareas, and has very important application prospect.