77 results about "Regeneration tissue" patented technology

A system for stimulating tissue to relieve pain and repair and/or regenerate tissue comprising a garment that has an electrode, a programmable electrical stimulation device, a time varying electromagnetic field generator, and a source that provides an electrical current. Also provided is a method wherein the electrode provides the user with a stimulating current and the time varying electromagnetic field provides the user with a time varying electromagnetic field either simultaneously, alternating, and/or sequentially.

The present invention discloses methods and compositions comprising a biocompatible gel that is used in tissue repair and regeneration. Once the gel is administered to a tissue site in need of repair or regeneration, the cells migrate from the gel into the tissue and repair or regenerate the tissue.

The present invention provides methods and compositions for sequentially and separately reducing infection and/or inflammation and regenerating tissue at a lesion site, by contacting the lesion site with a biodegradable scaffold that first delivers one or more agents at the lesion site to reduce infection and/or inflammation and then delivers one or more agents to regenerate tissue at the lesion site after inflammation is reduced.

The object of the present invention is to provide: a hybrid material for regeneration of living body tissue, which can retain sufficient mechanical strength for a term needed to regenerate the tissue, and which simultaneously has moderate biodegradation absorbability which enables degradation and disappearance rapidly after the regeneration of the tissue. As means for solving the problems, the hybrid material for regeneration of living body tissue, according to the present invention, comprises a naturally-occurring polymer and a biodegradation-absorbable synthetic polymer, wherein the biodegradation-absorbable synthetic polymer exists in a fibrous form in a sponge including the naturally-occurring polymer, and wherein the naturally-occurring polymer is crosslinked.

The invention provides a medical collagen material, a manufacturing method and the application of the medial collagen material. The medical collagen material is provided with a prismatic artificial ligament/hamstring tendon with seams and a platy film provided with dense pores. The artificial prismatic ligament/hamstring tendon is provided with the longitudinal pore that is specifically sized. The artificial prismatic ligament/hamstring tendon and the platy film are used for connecting and wrapping injured sutured part. The medical collagen material has the characteristics of stable structure, good biocompatibility and the ability of degradation and absorption and can reduce or prevent tissue adhesion.

The invention relates to a biphysic tissue engineering joint scaffold as well as a preparation method and an application thereof. The biphysic tissue engineering joint scaffold consists of a phrenology scaffold and a cartilage scaffold, wherein the cartilage scaffold is a PGA/PLA scaffold; the phrenology scaffold is a PCL/HA scaffold. The invention also provides a biphysic cell-tissue engineering joint scaffold constructor as well as a preparation method and an application thereof. The biphysic tissue engineering joint scaffold as well as the preparation method and the application thereof have the advantages that the biphysic tissue engineering joint scaffold is manufactured by utilizing a CAD/CAM technology, the external form and interior structure are accurate and controllable, the phrenology and the cartilage are matched with each other, the biphysic cell-tissue engineering joint scaffold constructor is formed by compositing seed cells by utilizing a tissue engineering technology, the tissue engineering joint can be regenerated in vivo and has the biological and mechanical biomechanical characteristics of the normal joint, an interface of a regenerated bones and the cartilage is well integrated, and the possibility is provided for performing biological reconstruction through the tissue engineering joint instead of the existing artificial joint.

A crosslinked elastin, a water-soluble crosslinking agent to be used for crosslinking, molded elastin articles, medical instruments and regeneration tissues using the crosslinked elastin, and a surgical therapy method and regeneration treatment wherein the medical instruments are employed. There is provided a biocompatible functional material having elasticity suitable for transplantation into the body without causing detachment of cell adhesion proteins.

The production process of human body tissue engineering carrier frame includes the following steps: firstly, preparing liquor containing tissue engineering carrier frame material and liquid containing growth factor at room temp., according to the user's requirements and previously designed and defined pathway extruding or jetting the above-mentioned two liquors respectively by means of different sprayers in the low-temp. environment of below zero deg.C, and making them form layer-by-layer stacked frozen porous tissue engineering carrier frame, then freeze-dried in freeze-drying machine, removing solvent so as to obtain the invented tissue engineering carrier frame. Its formation process and porosity structure of the frame, and the pore size and its through property can be well controlled,so that it is favorable for internal degradation of carrier frame in human body and nutrition and metabolism of regenerated tissue, and can well retain the bio-activity of biological material.

The invention discloses a Chinese material medica preparation for treating bedsore and a preparation method thereof. The amount of components of the preparation is obtained from long-term experience and summarization of the inventor, and the following components have good curative effect by the following weight: astragalus root, panax ginseng, viola herb, dandelion, honeysuckle, frosythia fruit, angelica, white peony root, red salvia root, peach kernel, safflower, purple gromwell root, dragon's blood and pearl powder and elephant skin powder. The preparation method combines the panax ginseng and the astragalus root, and combines the medicines to cause each pharmaceutical efficacy to produce synergetic effect, thus effectively replenishing qi to invigorate the spleen, and supporting the healthy energy. Main functions are supplementing qi and activating blood circulation, clear away heat and toxic materials, removing putrefaction and promoting tissue regeneration, dissipating blood stasis, and promoting regeneration tissue for astringency. Compared with the prior art, the Chinese material medica preparation has advantages of having little side effect, addressing both the symptoms androot causes, and effectively treating bedsore for employing the technical proposal.

A graft containing a scaffold that includes a matrix in which are positioned mesenchymal progenitor cells (MPCs) has the capacity to substantially improve wound healing, including wounds resulting from injury to nerve, bone and vascular tissue. MPCs can be harvested from debrided muscle tissue following orthopaedic trauma. The traumatized muscle-derived progenitor cells are a readily available autologous cell source that can be utilized to effect or improve wound healing in a variety of therapeutic settings and vehicles.

The invention provides a three-dimensional space cell culture system preparation method. A fine chain is placed in an outer casing pipe, biological degradable materials are melted and then filled in the outer casing pipe, and after the biological degradable materials are solidified and sized, the outer casing pipe and the fine chain are removed, so that a three-dimensional cell culture unit is prepared. The three-dimensional space culture unit prepared by the method can be applied in long-period cell culturing and a large amount of cells generating, the large amount of cells serve as seed cells of tissue engineering, and the three-dimensional space culture unit can be applied in transplant treatment by generating regeneration tissue and micro-organs in a short time.

Proteins which are upregulated in injured or regenerating tissues, as well as the DNA encoding these proteins, are disclosed, as well as therapeutic compositions and methods of treatment encompassing these compounds.

The invention relates to a Chinese medicinal composition for treating dental ulcers, which belongs to the field of traditional Chinese medicines. The Chinese medicinal composition for treating dental ulcers is prepared from the following raw medicinal materials in portions by weight: 10-120 portions of indigo naturalis, 5-30 portions of calculus bovis, 5-15 portions of gallnut, 5-15 portions of borneol, 2-10 portions of chalcanthite, 1-5 portions of coptis chinensis and 1-5 portions of field mint. In the invention, the Chinese medicinal composition is prepared into other preparation formulation on the basis of fundamental principles of clearing heat, detoxicating, reducing swelling, relieving pain and promoting regeneration tissue for astringency. According to the clinical application, the Chinese medicinal composition has no any side effect and has a reliable therapeutic effect.

The invention provides an MS-free tissue culture method for bananas. Clump shoot regeneration tissue culture liquid, subculture tissue culture liquid and root taking tissue culture liquid are adopted in the clump shoot regeneration stage, the subculture stage and the root taking culture stage of bananas respectively, and the lump shoot regeneration tissue culture liquid, the subculture tissue culture liquid and the root taking tissue culture liquid all contain a cassava alcohol anaerobic fermentation liquid culture medium. The technical scheme is adopted, cassava alcohol anaerobic fermentation liquid is used for replacing a basic culture medium MS, normal growth in three different stages of banana tissue culture is not affected at all, production cost is greatly reduced, waste is turned into valuable materials, the method is more environmentally friendly in the aspect of ecological environment, cultured banana seedlings can achieve the effect of seedlings which are cultured through MS tissue culture in the prior art, the root taking amount is larger, roots are thicker and stronger, the period of seedling establishment is earlier than that of the seedlings cultured through the basic MS culture medium, transplantation and survival of tissue culture seedlings are easier, and favorable conditions are provided for large-scale tissue culture production.