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74 results about "Sequence mapping" patented technology

Systems and methods to detect copy number variation

In one aspect, a system for implementing a copy number variation analysis method, is disclosed. The system can include a nucleic acid sequencer and a computing device in communications with the nucleic acid sequencer. The nucleic acid sequencer can be configured to interrogate a sample to produce a nucleic acid sequence data file containing a plurality of nucleic acid sequence reads. In various embodiments, the computing device can be a workstation, mainframe computer, personal computer, mobile device, etc.
The computing device can comprise a sequencing mapping engine, a coverage normalization engine, a segmentation engine and a copy number variation identification engine. The sequence mapping engine can be configured to align the plurality of nucleic acid sequence reads to a reference sequence, wherein the aligned nucleic acid sequence reads merge to form a plurality of chromosomal regions. The coverage normalization engine can be configured to divide each chromosomal region into one or more non-overlapping window regions, determine nucleic acid sequence read coverage for each window region and normalize the nucleic acid sequence read coverage determined for each window region to correct for bias. The segmentation engine can be configured to convert the normalized nucleic acid sequence read coverage for each window region to discrete copy number states. The copy number variation identification engine can be configured to identify copy number variation in the chromosomal regions by utilizing the copy number states of each window region.
Owner:LIFE TECH CORP

Sequencing sequence mapping method and sequencing sequence mapping system

The invention discloses a sequencing sequence mapping method and sequencing sequence mapping system. The method comprises the steps that pretreatment is performed on a reference genome so as to generate a reference genome compression structure, an address index structure and a halving point index structure; the reference genome compression structure stores the whole reference genome in a compression mode, the address index structure address stores address values of all subsequences in the reference genome based on a certain sequence, and the halving point index structure is used for storing positions, where part of the address values exists, in the address index structure and used for achieving initial positioning of a sequencing sequence in an acceleration mode; based on the characteristics of the reference genome, the whole information of the sequencing sequence and the polymorphic occurrence conditions of a belonged specie of the sequencing sequence, an algorithm parameter is mapped according to probabilistic design so that the requirements for sensitivity, specificity and a mapping speed can be met or compromised. The structure is obtained through pretreatment, all sequencing sequences are mapped on the reference genome through subsequence positioning, prolongation based on the self-matching function and the step of quantitative analysis.
Owner:ACAD OF MATHEMATICS & SYSTEMS SCIENCE - CHINESE ACAD OF SCI

Method for dynamically constructing online thematic map

The invention relates to the technical field of network maps and space information service, in particular to a method for dynamically constructing an online thematic map. The method comprises the following steps of: constructing a sequenced mapping among three sets, namely a statistical index, a visual variable and a map sign by performing online organization and dynamic modeling on heterogeneous distributed statistic index data by a method for drawing a multi-variable map so as to integrate to form a drawing rule set in which a gathering visual variable is used as a core characteristic; and formalizing description language by using extensible markup language (XML) as a network map sign, dynamically constructing a personal thematic map by using a format of a network thematic map service combination, and forming the online thematic map in a logic layer model organization of a map group, a map picture and an illustration, which is detailed step by step. By the method, a map expression acquired by the user comprises dynamic customization expressed in the forms of a map sign, a color and the like, so the humanized requirement of the map user can be fully met; and aiming at users on different levels, the thematic maps meeting the service requirements can be designed, and the effect is remarkable.
Owner:WUHAN UNIV

Rapid analysis method and system for genomes of pathogenic microorganisms

The invention discloses a rapid analysis method for genomes of pathogenic microorganisms and a data analysis platform. The method provides typing and source-tracing functions of bacterial genome sequences based on a bacterial strain database system. A user can only set simple parameters and upload bacterial strain genome sequences. The system can feed back the MLST parting result of bacterial strains, medicine resistance and distribution of virulence genes within the shortest time and make reference to names of bacterial strains and provide phylogenetic trees of all bacterial strains which are uploaded by a user and arranged in a database. The method is suitable for the establishment of a data analysis platform for pathogeny microbiology which integrates study of genetics, genomics and phylogenetics. Compared with the conventional typing technology, the rapid analysis method and system for genomes of pathogenic microorganisms have the following beneficial effects: higher resolution is obtained; bacterial strains of the same clone can be accurately detected; the feedback speed of results is high; and the technology of efficient reference strain setting and genome SNP sequence mapping, data analysis results can be quickly obtained by a user, thereby facilitating real-time tracking and fast source-tracing of clonal spreads in pathogenic microorganisms.
Owner:ZHEJIANG UNIV

Chaotic hybrid spread spectrum secure underwater acoustic communication method

The invention discloses a chaotic hybrid spread spectrum secure underwater acoustic communication method. The method comprises the following steps: 1) a transmitting end uniformly groups a binary sequence sent by an information source, each group is divided into three blocks, the first block is subjected to BPSK modulation and Gray mapping, the second block is subjected to M-element chaotic phase modulation CPM spread spectrum sequence mapping, and the third block is modulated into a chaotic frequency modulation spread spectrum CFM signal; mixing and modulating the output three types of orthogonal signals to obtain a chaotic mixed spread spectrum CHSS signal to be transmitted, and converting the CHSS signal into an analog signal for transmission; 2) converting the received underwater acoustic analog signal into a digital signal by the receiving end, using an in-phase branch BPSK spread spectrum signal in chaotic phase modulation spread spectrum as a pilot signal, and performing time-frequency two-dimensional search on the signal by using the spread spectrum gain of the chaotic phase modulation spread spectrum code to complete time-frequency synchronization; and demodulating the signal after time-frequency synchronization, adopting an incoherent maximum likelihood demodulation algorithm for M-element CPM and CFM spread spectrum, and adopting a coherent demodulation algorithm for BPSK to complete M-element despreading and coherent demodulation, thereby obtaining a binary sequence.
Owner:INST OF ACOUSTICS CHINESE ACAD OF SCI

OOFDM (Optical Orthogonal Frequency Division Multiplexing) encryption system based on chaos sequence mapping

The invention discloses an OOFDM (Optical Orthogonal Frequency Division Multiplexing) encryption system based on chaos sequence mapping; the OOFDM encryption system comprises a chaos sequence mapping based encrypting optical emission module, an optical fiber transmission module and a chaos sequence mapping based decrypting optical receiving module; the optical emission module, the optical fiber transmission module and the optical receiving module are successively connected; the chaos sequence mapping based encrypting optical emission module comprises a chaos encryption unit and an OFDM (Orthogonal Frequency Division Multiplexing) modulation unit, wherein the chaos encryption unit is connected with one end of the optical fiber transmission module via the OFDM modulation unit; the chaos sequence mapping based decrypting optical receiving module comprises a chaos decryption unit and an ODFM demodulation unit; and the other end of the optical fiber transmission module is connected with the chaos decryption unit via the ODFM demodulation unit. According to the OOFDM encryption system disclosed by the invention, by fully utilizing the characteristics of a chaos system to initial value sensitivity, the safety of the encryption is greatly improved; and while the orthogonality of OFDM modulation is kept relatively well, the damage to system performance due to encryption is reduced.
Owner:嘉兴吉企贸易有限公司

Modulating method and device as well as demodulating method and device of GFDM (Generalized Frequency Division Multi-plex) signal

The embodiment of the invention provides a modulating method and device as well as a demodulating method and device of a GFDM (Generalized Frequency Division Multi-plex) signal. the modulating method comprises the following steps: acquiring an original signal to be modulated; shaping a pulse to obtain a random filter pulse; performing a cyclic convolution on a signal to be modulated sequence and the random filter pulse to obtain a first modulated signal; mapping the random filter pulse into a random phase sequence; returning a dot product of the first modulating signal and the random phase sequence for serving as a second modulating signal till circular times are up to a preset value; calculating a peak-to-average power ratio of each path of a time-domain signal; and determining a path of the time-domain signal with lowest peak-to-average power ratio as a modulated signal to be transmitted. As proved by the invention, through the pulse shaping and random phase sequence mapping, a path of the signal with the lowest peak-to-average power ratio can be determined as the signal to be transmitted, and the peak-to-average power ratio of the GFDM signal can be lowered remarkably.
Owner:BEIJING UNIV OF POSTS & TELECOMM

Parallel combined spread spectrum underwater acoustic communication method of interleaved Gold mapping sequence

The invention discloses a parallel combined spread spectrum underwater acoustic communication method of an interleaved Gold mapping sequence. The method comprises the following steps: step 1) selecting r information sequences from a spread spectrum sequence set according to a data-spread spectrum sequence mapping table at a signal transmitting end to perform multichannel interleaving to generate an information mapping sequence, selecting a sequence that is not related to the sequences in the spread spectrum sequence set as a synchronizing sequence, transmitting the synchronizing sequence andthe information mapping sequence into an underwater acoustic channel after performing quadrature modulation; and step 2) demodulating received signals to a complex baseband at a signal receiving end,performing Doppler compensation to obtain a received signal sequence, then obtaining L multichannel parameters by using the operation results of the synchronizing sequence and the received signal sequence, performing de-interleaving and multichannel merging on the received signal sequence by using these parameters, and performing operation to obtain r sequences, respectively performing maximum value calculation judgment on the r sequences by using M paths of correlators to obtain judgment symbols of transmitting sequences, and then obtaining sequence numbers of the transmitted r information sequences.
Owner:INST OF ACOUSTICS CHINESE ACAD OF SCI

Scheduling method and device for resources in distributed system

The invention discloses a scheduling method for resources in a distributed system. The method comprises the following steps that: receiving an application request from a job party to apply for resources, wherein the application request comprises corresponding resource identification for applying for the resources; extracting the resource identification contained in the application request; analyzing the extracted resource identification, comparing with a pre-established resource identification-identification sequence mapping relationship to obtain a to-be-screened identification sequence corresponding to the application request; utilizing a screening algorithm to screen an identification sequence matched with the analyzed resource identification from the to-be-screened identification sequence; comparing the screened identification sequence with the pre-established resource identification-identification sequence mapping relationship to determine resources corresponding to the application request; and distributing the resources corresponding to the application request to the job party. When resource scheduling is carried out on the basis of the method, according to the resource identification contained in the application request, corresponding resources are distributed, and resource scheduling flexibility is higher.
Owner:ALIBABA CLOUD COMPUTING LTD

TDD-LTE (Time Division Duplexing-Long Term Evolution) synchronization method, device, system, apparatus and storage medium

The embodiments of the invention disclose a TDD-LTE (Time Division Duplexing-Long Term Evolution) synchronization method, a TDD-LTE (Time Division Duplexing-Long Term Evolution) synchronization device, a TDD-LTE (Time Division Duplexing-Long Term Evolution) synchronization system, an apparatus and a storage medium. The method includes the following steps that: under a condition that the number ofsymbols in a preset occupiable time-domain location range is smaller than or equal to the difference value of the preset number of symbols occupied by downlink time slots and the number of reserved symbols, if the number of the symbols is smaller than or equal to the difference value of the number of symbols included in one time slot and the number of the reserved symbols, the time-domain locationof a primary synchronization signal sequence mapping corresponding to a transmitting physical cell is determined; if the number of the symbols is greater than the difference value, the time-domain location of a primary synchronization signal sequence mapping corresponding to the transmitting physical cell is determined according to the result of comparison between the calculation result of a first calculation standard and a threshold; and the time-domain resource and frequency-domain resource of a primary synchronization signal sequence and a secondary synchronization signal sequence corresponding to the transmitting physical cell are determined. With the method, device, system, apparatus and storage medium provided by the embodiments of the present invention adopted, more primary synchronization signal physical resources can be provided, and the receiving quality of the primary synchronization signal sequence can be improved.
Owner:BEIJING XINWEI TELECOM TECH +1
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