37 results about "Skin blood flow" patented technology

The present invention is capable of separating/removing the influence of skin blood flow contained in near infrared spectroscopy (NIRS) signals and extracting a brain- or brain cortex-origin signal. Moreover, the present invention enables versatile separation of brain-origin and skin-origin signals in view of differences among individuals. A biological photometric device, wherein light transmitters and light receivers are located in such a manner that measurement can be conducted at a plurality of source-detector (SD) distances and light received by the individual light-receivers can pass through the gray matter to thereby separate a brain-origin signal and a skin-origin signal. Individual component analysis (ICA) is conducted on data obtained at the individual measurement points. Then, it is determined whether each individual component originates in the brain or in the skin with the use of the SD distance-dependency of the weighted value of each of the separated components.

A hypobaric chamber is adapted to receive the affected body part to be treated through an entry port formed in one wall of the chamber. An aperture is formed at the entry port for creating a loose, non-occlusive seal around the body part of the patient, the aperture comprising an adjustable iris formed from a pliable material attached to the edges of the entry port and having a center opening to which are attached the inner ends of a plurality of iris leaves or slides. The pliable material is stretched between the edges of the entry port and the inner ends of the slides to form a diaphragm-like structure. In the preferred embodiment, the pliable material is latex or some other rubber-like material. The seal is adjustable by moving the slides radially to adjust the portion of the port that is covered by the pliable material. The inner edges of the slides are positioned so that a small gap exists between the skin and the edge of the seal, allowing unrestricted air flow-through. The leak created by the loose seal is overcome by a high-volume pump which is connected to the chamber via appropriate vacuum tubing. The chamber pressure is reduced to create a mild negative pressure, on the order of −50 mmHg or less below ambient pressure.

Topical drug delivery formulations with optical amounts of vasodilator. Vasodilator chemicals applied topically dilate the blood vessels in the skin tissue, which have been shown to facilitate or inhibit systemic or skin tissue deposition of drug substances. The level of stimulation and/or inhibition has been found to be dependent on the concentration and the identity of the specific vasodilator chemical(s) used as well as the drug molecule(s) to be delivered. This work teaches the need to consider specific formulation requirements when dealing with vasodilator chemicals for the creation of successful delivery vehicles in the transdermal drug delivery system. These requirements for very low concentrations of vasodilators were an unexpected and a surprise finding, in contrast to the concentrations of the vasodilators typically used to elicit an increase in skin blood flow.

The present invention relates to footwear in which natural germanium ore powder is added to the uppers of leather portion (an outer cover, an inner cover and a middle cover) and sole portions (an inner sole, a Taxon portion, a middle sole and a bottom sole) in all kinds of footwear such as shoes, running shoes, golf shoes, indoor shoes, sandals and work shoes. Germanium (Ge) is a material that emits a large amount of far-infrared rays. Germanium has a thermo effect of the human body and efficacy of promoting equilibrium of the autonomic nervous system and the amount of skin blood flow. Further, germanium has effects that it promotes circulation of blood and metabolism, shuts electromagnetic waves and prevents static electricity.

A non-invasive detection system with a peripheral vascular blood flow adjusting function comprises a data collecting module, a filtering module, a feature point/section identification module, a data analysis module and a blood flow adjusting function evaluation module. Cuff downstream front arm or hand skin blood flow volume signals are continuously measured before and after blood flow of the brachial artery is blocked by means of the method that the unilateral upper arm is pressurized through a cuff, after the blood flow volume signals are subjected to filtering treatment, a stable blood flow section before compression of the cuff and a congestion section after relieving of cuff compression are identified, and the specific value of average blood flow volumes of the congestion section and the stable blood flow section is calculated to obtain the index of quantitative evaluation for the peripheral vascular blood flow adjusting function. The non-invasive effect is achieved in the whole operating process, the measuring time is short, through feature analysis for a time registration curve of the blood flow, a blood flow changing section dominated by peripheral vascular ischemic reaction is identified, the influence of the upstream artery endothelial function on peripheral blood flow signals can be effectively excluded to achieve targeted evaluation on the human body peripheral vascular blood flow adjusting function, and the pretty good application prospects are achieved.

Visible light is a treatment option for Segmental Vitiligo (SV), and visible light-induced repigmentation is associated normalization of sympathetic. Currently it is difficult to predict individual patient's response to visible light therapy. Therefore, the present invention uses the Laser Doppler Flowmeter to serve as a response predictor for visible light on treating SV. The present invention recruited 14 Segmental Vitiligo patients for evaluating clinical information. FirstLaser Doppler Flowmeter was used to evaluate the cutaneous blood flow of SV lesion and contralateral normal skin, and then treated them with visible light irradiate, cold-stress, rewarmed, and recorded the change of skin blood flow, finally the patients received regular visible light treatment for 3 months, and patients have a sign of repigmentation after the treatment.

A method for determining and demonstrating the role of vasodilator chemical agents in the development and practice of transdermal drug delivery systems. Vasodilator chemicals applied topically dilate the blood vessels in the skin tissue, which have been shown to facilitate or inhibit systemic or skin tissue deposition of drug substances. The level of stimulation and/or inhibition has been found to be dependent on the concentration and the identity of the specific vasodilator chemical(s) used as well as the drug molecule(s) to be delivered. This work teaches the need to consider specific formulation requirements when dealing with vasodilator chemicals for the creation of successful delivery vehicles in the transdermal drug delivery system. These requirements for very low concentrations of vasodilators were an unexpected and a surprise finding, in contrast to the concentrations of the vasodilators typically used to elicit an increase in skin blood flow.

The invention provides vasodilating medication as means for lowering fever when administered to humans in need of such treatment. In particular, the use of B3 vitamin substances and Nitric Oxide-donor ingredients in compositions intended for use in reducing fever is introduced. The core composition substances can be used effectively on their own. Yet, in combination with anti-pyretic substances such as Aspirin, Acetaminophen, and Ibuprofen, the present invention enables the use of reduced dosage of composing substances for achievement of desired fever reduction effect. In addition, an optional addition of sweat inducing plant extracts in any of the noted compositions leads to a synergistic effect of reducing fever by increase of both skin blood flow and perspiration.

An improved skin blood flow measurement apparatus consists of a chassis with an antenna connected with the chassis such that the antenna directs RF energy at an area of a skin surface below the chassis. A temperature sensor is also connected with the chassis such that the temperature sensor is held in fixed relation to the antenna and such that the temperature sensor is also directed to the same said area of a skin surface below the chassis for measurement of temperature of the area and further where the temperature sensor does not contact the skin surface and where the chassis supports the antenna and the temperature sensor in fixed relation to the area.

Signals derived from the brain or cerebral cortex are extracted by separating and removing influence of the skin blood flow included in NIRS signals. Provided is a biophotonic measurement apparatus to separate signals simultaneously measured with a plurality of irradiator-detector distances (SD distances) into brain blood flow-derived signals and skin blood flow-derived signals using SD distance dependency of signal amplitudes.

The invention discloses a monitoring imaging method and system for skin blood flow and blood vessels, and a storage medium. The method comprises the following steps: collecting skin thermal images through a thermal infrared imager; performing image preprocessing according to the skin thermal images to obtain thermal signals; converting the thermal signals into corresponding blood flow signals by using a wavelet filtering algorithm; and mapping the blood flow signals into pixel points of each frame to complete blood vessel function imaging, wherein imaging comprises blood vessel endothelial regulation function imaging, blood vessel nerve regulation function imaging, blood vessel myogenic regulation function imaging and skin blood flow distribution imaging. According to the invention, large-area, anti-interference, simple and rapid monitoring of skin blood flow can be realized at a reasonable cost, functional imaging can be carried out on various regulation activities such as blood vessel endothelial regulation, nerve regulation and myogenic regulation, and the method and system can be used for early detection of peripheral vascular structures and functional lesions and can be intensively applied to the field of medical instruments.

A photobiological measurement apparatus 1 may include a second received light quantity information calculation unit 33 for calculating measurement data relating to cerebral activity, a data display controller for displaying the measurement data for a specified area of a subject's brain, is characterized: is being provided with a reference light-receiving probe 14, which is disposed at a position separated by a first setting distance r1 from the light-transmitting prober 12 that is shorter than a second setting distance r2, and a first received light quantity information calculating unit 32, which calculates skin blood flow data relating to the skin blood flow using first received light quantity information ΔA1 from the light transmitting probe 12 to the reference light-receiving probe 14, and in displaying the skin blood flow data at a specified position of the subject's scalp by indicating the measurement position on the subject's scalp and displaying the skin blood data.

The invention relates to the technical field of medical equipment, in particular to a protective restraint monitoring system and a pressure ulcer evaluation method. The protective restraint monitoringsystem comprises an upper body restraint belt main body, an ankle restraint belt, a wrist restraint belt, and a data processing terminal; blood flow sensors, pressure sensors and temperature sensorsare embedded in inner walls of a neck restraint belt, shoulder restraint belts symmetrically disposed on both sides and waist restraint belts symmetrically disposed on both sides; and blood flow sensors, pressure sensors, and temperature sensors are embedded in the inner walls at two sides of the ankle restraint belt and inner walls at two sides of arms of the wrist restraint belt. Change data ofthe skin blood flow, the pressure and the temperature of a restraint part of a protective restraint patient can be calculated through the blood flow sensors, the pressure sensors, and the temperaturesensors; processing is performed by using a laser Doppler blood flow meter; data storage and analysis are performed by using a computer; and the protective restraint monitoring system effectively warns of the risk of pressure ulcers in long-term protective restraint parts and avoids complications.

The invention relates to a novel application of ferulic acid in treatment of radioactive skin injury, ferulic acid is prepared into a gel form, and the product has a good protection effect on cells and animal models damaged by <60> Co-gamma rays, has no stimulation effect on normal skin and can significantly enhance the oxidation resistance of HaCaT cells damaged by radiation. The ferulic acid gel is stable in physicochemical property, after the ferulic acid gel is used, the occurrence time of a skin wound is delayed, the red and swollen skin wound and the damaged area are reduced, and the skin blood flow at the wound is reduced than that of a non-medication group. The ferulic acid gel can inhibit activation of NLRP3 inflammasomes and reduce generation of inflammatory factors IL-18 and IL-1beta, so that inflammation is promoted to be relieved, injury edema is relieved, a good injury repairing effect on radioactive skin injury is achieved, and the technical effect of radiation resistance is achieved.

Provided is a cosmetic composition for scrubbing comprising scrub particles for increasing skin blood flow and removing a stratum corneum by being rubbed on the skin, wherein the scrub particles are bracken spores. When the cosmetic composition for scrubbing is rubbed on the skin, a plurality of polyps formed on surfaces of the bracken spores are broken, and thus, the cosmetic composition for scrubbing does not irritate the skin and has a good feeling of use and a uniform and excellent scrubbing effect.

The invention discloses a dual-mode imaging method and system for skin blood perfusion characterization, which can be used for monitoring skin blood perfusion and solves the problems that in the prior art, when skin blood perfusion is monitored, skin blood flow velocity distribution and blood volume pulse waves cannot be obtained at the same time, and skin blood perfusion cannot be comprehensively evaluated. According to the dual-mode imaging method for skin blood perfusion characterization, two video imaging systems are adopted for synchronous control, blood volume and laser speckle video images are collected in real time and synchronously processed, blood flow velocity distribution and blood volume pulse waves are obtained at the same time, and real-time and comprehensive monitoring of blood perfusion of the skin to be detected is achieved. In order to achieve the method, the invention further provides a dual-mode imaging system for skin blood perfusion characterization, and the system comprises a laser light source, a collimation beam expander, a green light source, a beam splitter, a first optical filter, a first video imaging module, a second optical filter, a polaroid and a second video imaging module.

The invention discloses a skin microvascular reactivity test system and method based on local pressure induction, and provides a skin microvascular reactivity test system based on local pressure induction, a data acquisition module of the system comprises a pressure stimulation device and a skin blood flow detector, a pressure stimulation part and a blood flow detection part are kept consistent, the influence of other interference factors participating in adjustment is naturally shielded, the blood flow adjustment capacity of skin microvessels is accurately reflected, local pressure stimulation on a target position is achieved through the pressure stimulation device, large stimulation and discomfort caused to a tester can be avoided, and the test accuracy is improved. And inapplicable people such as hypertension and unstable vascular plaque patients do not exist. Under the condition that a tester is prevented from feeling uncomfortable, the blood flow characteristic signals are obtained through testing in the mode that reactive hyperemia is induced through local pressure, then the blood flow adjusting capacity of the skin microvessels can be evaluated, and the method can be widely applied to the technical field of biomedical engineering.