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37 results about "Skin blood flow" patented technology
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Sympathetic neural control of skin blood flow includes the noradrenergic vasoconstrictor system and a sympathetic active vasodilator system, the latter of which is responsible for 80% to 90% of the substantial cutaneous vasodilation that occurs with whole body heat stress. With body heating, the magnitude of skin vasodilation is striking: skin blood flow can reach 6 to 8 L/min during hyperthermia.
Biological photometric device and biological photometry method using same
ActiveUS20130102907A1Increase distanceAccurate identificationDiagnostics using spectroscopyScattering properties measurementsMeasurement pointMedicine
The present invention is capable of separating / removing the influence of skin blood flow contained in near infrared spectroscopy (NIRS) signals and extracting a brain- or brain cortex-origin signal. Moreover, the present invention enables versatile separation of brain-origin and skin-origin signals in view of differences among individuals. A biological photometric device, wherein light transmitters and light receivers are located in such a manner that measurement can be conducted at a plurality of source-detector (SD) distances and light received by the individual light-receivers can pass through the gray matter to thereby separate a brain-origin signal and a skin-origin signal. Individual component analysis (ICA) is conducted on data obtained at the individual measurement points. Then, it is determined whether each individual component originates in the brain or in the skin with the use of the SD distance-dependency of the weighted value of each of the separated components.
Owner:FUJIFILM HEALTHCARE CORP
Method and device to enhance skin blood flow
InactiveUS20060100556A1Increase heightAvoid occlusionPneumatic massageVibration massageVeinAmbient pressure
A hypobaric chamber is adapted to receive the affected body part to be treated through an entry port formed in one wall of the chamber. An aperture is formed at the entry port for creating a loose, non-occlusive seal around the body part of the patient, the aperture comprising an adjustable iris formed from a pliable material attached to the edges of the entry port and having a center opening to which are attached the inner ends of a plurality of iris leaves or slides. The pliable material is stretched between the edges of the entry port and the inner ends of the slides to form a diaphragm-like structure. In the preferred embodiment, the pliable material is latex or some other rubber-like material. The seal is adjustable by moving the slides radially to adjust the portion of the port that is covered by the pliable material. The inner edges of the slides are positioned so that a small gap exists between the skin and the edge of the seal, allowing unrestricted air flow-through. The leak created by the loose seal is overcome by a high-volume pump which is connected to the chamber via appropriate vacuum tubing. The chamber pressure is reduced to create a mild negative pressure, on the order of −50 mmHg or less below ambient pressure.
Owner:RGT UNIV OF CALIFORNIA
Transdermal drug delivery formulations with optimal amounts of vasodilators therein
InactiveUS20060013866A1Maximize efficiencyEasy to transportSalicyclic acid active ingredientsBiocideVascular dilatationDelivery vehicle
Topical drug delivery formulations with optical amounts of vasodilator. Vasodilator chemicals applied topically dilate the blood vessels in the skin tissue, which have been shown to facilitate or inhibit systemic or skin tissue deposition of drug substances. The level of stimulation and / or inhibition has been found to be dependent on the concentration and the identity of the specific vasodilator chemical(s) used as well as the drug molecule(s) to be delivered. This work teaches the need to consider specific formulation requirements when dealing with vasodilator chemicals for the creation of successful delivery vehicles in the transdermal drug delivery system. These requirements for very low concentrations of vasodilators were an unexpected and a surprise finding, in contrast to the concentrations of the vasodilators typically used to elicit an increase in skin blood flow.
Owner:BIOCHEMICS
Shoes included natural germanium
InactiveUS20060141180A1Avoid problemsLong-term useEnvelopes/bags making machinerySolesNervous systemEngineering
The present invention relates to footwear in which natural germanium ore powder is added to the uppers of leather portion (an outer cover, an inner cover and a middle cover) and sole portions (an inner sole, a Taxon portion, a middle sole and a bottom sole) in all kinds of footwear such as shoes, running shoes, golf shoes, indoor shoes, sandals and work shoes. Germanium (Ge) is a material that emits a large amount of far-infrared rays. Germanium has a thermo effect of the human body and efficacy of promoting equilibrium of the autonomic nervous system and the amount of skin blood flow. Further, germanium has effects that it promotes circulation of blood and metabolism, shuts electromagnetic waves and prevents static electricity.
Owner:PARK JU SIK
Biological photometric device and biological photometry method using same
ActiveCN103153198ASD distance dependentHigh precision separationSurgeryDiagnostics using spectroscopyGrey substanceBiological body
Owner:HITACHI HEALTHCARE MFG LTD
Non-invasive detection system with peripheral vascular blood flow adjusting function
ActiveCN107411778AReduce uncertainty errorImprove reliabilityBlood flow measurement devicesInfrasonic diagnosticsNon invasiveData acquisition module
A non-invasive detection system with a peripheral vascular blood flow adjusting function comprises a data collecting module, a filtering module, a feature point / section identification module, a data analysis module and a blood flow adjusting function evaluation module. Cuff downstream front arm or hand skin blood flow volume signals are continuously measured before and after blood flow of the brachial artery is blocked by means of the method that the unilateral upper arm is pressurized through a cuff, after the blood flow volume signals are subjected to filtering treatment, a stable blood flow section before compression of the cuff and a congestion section after relieving of cuff compression are identified, and the specific value of average blood flow volumes of the congestion section and the stable blood flow section is calculated to obtain the index of quantitative evaluation for the peripheral vascular blood flow adjusting function. The non-invasive effect is achieved in the whole operating process, the measuring time is short, through feature analysis for a time registration curve of the blood flow, a blood flow changing section dominated by peripheral vascular ischemic reaction is identified, the influence of the upstream artery endothelial function on peripheral blood flow signals can be effectively excluded to achieve targeted evaluation on the human body peripheral vascular blood flow adjusting function, and the pretty good application prospects are achieved.
Owner:SHANGHAI JIAO TONG UNIV
Biological photometric device and biological photometry method using same
ActiveUS9198624B2Discriminate the signal from the brainAccurate identificationDiagnostics using spectroscopyScattering properties measurementsMeasurement pointPrincipal component analysis
The present invention is capable of separating / removing the influence of skin blood flow contained in near infrared spectroscopy (NIRS) signals and extracting a brain- or brain cortex-origin signal. Moreover, the present invention enables versatile separation of brain-origin and skin-origin signals in view of differences among individuals. A biological photometric device, wherein light transmitters and light receivers are located in such a manner that measurement can be conducted at a plurality of source-detector (SD) distances and light received by the individual light-receivers can pass through the gray matter to thereby separate a brain-origin signal and a skin-origin signal. Individual component analysis (ICA) is conducted on data obtained at the individual measurement points. Then, it is determined whether each individual component originates in the brain or in the skin with the use of the SD distance-dependency of the weighted value of each of the separated components.
Owner:FUJIFILM HEALTHCARE CORP
Noninvasive cutaneous blood flow assessment as a response predictor for visible light therapy on segmental vitiligo
Visible light is a treatment option for Segmental Vitiligo (SV), and visible light-induced repigmentation is associated normalization of sympathetic. Currently it is difficult to predict individual patient's response to visible light therapy. Therefore, the present invention uses the Laser Doppler Flowmeter to serve as a response predictor for visible light on treating SV. The present invention recruited 14 Segmental Vitiligo patients for evaluating clinical information. FirstLaser Doppler Flowmeter was used to evaluate the cutaneous blood flow of SV lesion and contralateral normal skin, and then treated them with visible light irradiate, cold-stress, rewarmed, and recorded the change of skin blood flow, finally the patients received regular visible light treatment for 3 months, and patients have a sign of repigmentation after the treatment.
Owner:KAOHSIUNG MEDICAL UNIVERSITY
Transdermal drug delivery formulations and method of determining optimal amounts of vasodilators therein
InactiveUS20060013769A1Maximize efficiencyEasy to transportCompounds screening/testingOrganic active ingredientsVascular dilatationWhole body
A method for determining and demonstrating the role of vasodilator chemical agents in the development and practice of transdermal drug delivery systems. Vasodilator chemicals applied topically dilate the blood vessels in the skin tissue, which have been shown to facilitate or inhibit systemic or skin tissue deposition of drug substances. The level of stimulation and / or inhibition has been found to be dependent on the concentration and the identity of the specific vasodilator chemical(s) used as well as the drug molecule(s) to be delivered. This work teaches the need to consider specific formulation requirements when dealing with vasodilator chemicals for the creation of successful delivery vehicles in the transdermal drug delivery system. These requirements for very low concentrations of vasodilators were an unexpected and a surprise finding, in contrast to the concentrations of the vasodilators typically used to elicit an increase in skin blood flow.
Owner:BIOCHEMICS
Noninvasive cutaneous blood flow assessment as a response predictor for visible light therapy on segmental vitiligo
Owner:KAOHSIUNG MEDICAL UNIVERSITY
Cutaneous blood flow monitoring device
InactiveUS20180146866A1Efficient measurementIncrease contactBlood flow measurement devicesEvaluation of blood vesselsBlood flowPhotonics
A method and a device for diagnostic of skin cancer and other mammalian skin tissue pathologies are described. The method relies on determination of pathological changes in tissue vascularization and capillary blood flow. The device uses photonic or ultrasound emitters and detectors to characterize temporal and spatial changes in blood flow associated with pulsative actions of the heart.
Owner:VERISKIN INC
Portable human psychological activity evaluator
InactiveCN107334480AScientifically Accurate Biomarker DataCompact structureSensorsPsychotechnic devicesHuman bodyNervous system
The invention provides a portable human psychological activity evaluator. The portable human psychological activity evaluator comprises an evaluator body and a panel, wherein a touch screen and a power source button are arranged on the panel; a peripheral interface is formed in the side face of the evaluator body and comprises a first sensor, a second sensor and a USB interface, and a circuit board is arranged in the evaluator body and comprises a power source, a skin blood flow detecting module, a skin potential electric performance detecting module, a processor with a system, a storage and a wireless communication module. By adopting the method of testing human body palm or sole skin evoked potential electric performance and microcirculation, physical signs related to activity and reaction of the surrounding sympathetic nervous system are detected comprehensively, scientific and accurate biomarker data is provided for evaluation and diagnosis of human neuropsychology activity, and the portable human psychological activity evaluator is small in structure, light, easy to operate and suitable for family practice or community medical rooms and does not need professional guidance.
Owner:湖州靖源信息技术有限公司
Anti-pyretic vasodilators
InactiveUS20100292280A1Substantial fever reductionDissipate quicklyBiocideAntipyreticVascular dilatationAdditive ingredient
The invention provides vasodilating medication as means for lowering fever when administered to humans in need of such treatment. In particular, the use of B3 vitamin substances and Nitric Oxide-donor ingredients in compositions intended for use in reducing fever is introduced. The core composition substances can be used effectively on their own. Yet, in combination with anti-pyretic substances such as Aspirin, Acetaminophen, and Ibuprofen, the present invention enables the use of reduced dosage of composing substances for achievement of desired fever reduction effect. In addition, an optional addition of sweat inducing plant extracts in any of the noted compositions leads to a synergistic effect of reducing fever by increase of both skin blood flow and perspiration.
Owner:ZACHAR ORON
Blood flow measurement apparatus and method
ActiveUS11293793B1Volume/mass flow measurementDiagnostic recording/measuringRadio frequency energyMechanical engineering
An improved skin blood flow measurement apparatus consists of a chassis with an antenna connected with the chassis such that the antenna directs RF energy at an area of a skin surface below the chassis. A temperature sensor is also connected with the chassis such that the temperature sensor is held in fixed relation to the antenna and such that the temperature sensor is also directed to the same said area of a skin surface below the chassis for measurement of temperature of the area and further where the temperature sensor does not contact the skin surface and where the chassis supports the antenna and the temperature sensor in fixed relation to the area.
Owner:UNIV OF SOUTH ALABAMA
Braking accelerator pedal stepping-by-mistake intelligent control system based on emotion recognition and control method thereof
InactiveCN107089139AEasy to operateImprove reliabilityAutomatic initiationsSensorsRecognition systemMicroprocessor
Provided are a braking accelerator pedal stepping-by-mistake intelligent control system based on emotion recognition and a control method thereof. A bioelectricity emotion recognition system is arranged on a steering wheel and comprises an Ag / Agcl nonpolar electrode for measuring skin resistance, a 15 microampere direct-current main connected with the Ag / Agcl nonpolar electrode, a Hematron sensor for measuring skin blood flow, and a first microprocessor connected with the Ag / Agcl nonpolar electrode and the Hematron sensor; a mechanical measurement system is arranged on an accelerator panel and comprises an acceleration sensor for measuring the movement speed of the accelerator panel, and a second microprocessor connected with the acceleration sensor; a central processor is arranged on a control panel of a vehicle and connected with the first microprocessor and the second microprocessor; and a braking control system is arranged on a braking plate and comprises a pressure bar, a controller used for controlling the pressure bar, and a fixing board; and the controller is connected with the central processor. Operation mistakes of a driver are comprehensively judged from the biological and physical results, and accordingly automatic emergent braking is provided, and accidents are avoided.
Owner:XI AN JIAOTONG UNIV
Acupuncture stimulation assessment method and system based on multi-physiological signal fusion real-time monitoring
PendingCN113456484AUnderstand the mechanism of actionAcupunctureSensorsHuman bodyAcupuncture treatment
The invention discloses an acupuncture stimulation assessment method and system based on multi-physiological signal fusion real-time monitoring. The method comprises the steps: assessing the acupuncture effect through the brain blood oxygen content, the skin blood oxygen saturation degree, the skin blood flow volume, the skin electrical activity value and the skin temperature. The system comprises a treatment bed; a computer is arranged on one side of the treatment bed, the computer is connected with a near infrared spectrum probe through a brain blood oxygen signal processor, and the computer is connected with a first skin blood oxygen probe and a second skin blood oxygen probe through a skin blood oxygen signal processor. The computer is connected with the first skin blood flow probe and the second skin blood flow probe through the skin blood flow signal processor and connected with the two skin conductivity sensors and the skin temperature sensor through the electrophysiological signal processor. The system has the advantages that the influence of acupuncture on various physiological parameters of the human body can be evaluated, doctors can understand the action mechanism of the bright acupuncture for treating the magic limb pain, and a basis is provided.
Owner:国家康复辅具研究中心
Biophotonic measurement apparatus and biophotonic measurement method using same
InactiveUS20160278643A1Efficient Data AcquisitionDiagnostics using spectroscopyOptical sensorsMedicineSkin blood flow
Signals derived from the brain or cerebral cortex are extracted by separating and removing influence of the skin blood flow included in NIRS signals. Provided is a biophotonic measurement apparatus to separate signals simultaneously measured with a plurality of irradiator-detector distances (SD distances) into brain blood flow-derived signals and skin blood flow-derived signals using SD distance dependency of signal amplitudes.
Owner:HITACHI LTD
Monitoring imaging method and system for skin blood flow and blood vessels, and storage medium
ActiveCN111012319ASimple and fast monitoringDiagnostic signal processingCatheterNeural regulationEngineering
The invention discloses a monitoring imaging method and system for skin blood flow and blood vessels, and a storage medium. The method comprises the following steps: collecting skin thermal images through a thermal infrared imager; performing image preprocessing according to the skin thermal images to obtain thermal signals; converting the thermal signals into corresponding blood flow signals by using a wavelet filtering algorithm; and mapping the blood flow signals into pixel points of each frame to complete blood vessel function imaging, wherein imaging comprises blood vessel endothelial regulation function imaging, blood vessel nerve regulation function imaging, blood vessel myogenic regulation function imaging and skin blood flow distribution imaging. According to the invention, large-area, anti-interference, simple and rapid monitoring of skin blood flow can be realized at a reasonable cost, functional imaging can be carried out on various regulation activities such as blood vessel endothelial regulation, nerve regulation and myogenic regulation, and the method and system can be used for early detection of peripheral vascular structures and functional lesions and can be intensively applied to the field of medical instruments.
Owner:GUANGDONG PROV MEDICAL INSTR INST
Photobiological measurement apparatus
A photobiological measurement apparatus 1 may include a second received light quantity information calculation unit 33 for calculating measurement data relating to cerebral activity, a data display controller for displaying the measurement data for a specified area of a subject's brain, is characterized: is being provided with a reference light-receiving probe 14, which is disposed at a position separated by a first setting distance r1 from the light-transmitting prober 12 that is shorter than a second setting distance r2, and a first received light quantity information calculating unit 32, which calculates skin blood flow data relating to the skin blood flow using first received light quantity information ΔA1 from the light transmitting probe 12 to the reference light-receiving probe 14, and in displaying the skin blood flow data at a specified position of the subject's scalp by indicating the measurement position on the subject's scalp and displaying the skin blood data.
Owner:SHIMADZU CORP
Protective restraint monitoring system and pressure ulcer evaluation method
InactiveCN109087700AEffective warning of the risk of pressure ulcersAvoid complicationsHealth-index calculationMedical automated diagnosisMedical equipmentEngineering
The invention relates to the technical field of medical equipment, in particular to a protective restraint monitoring system and a pressure ulcer evaluation method. The protective restraint monitoringsystem comprises an upper body restraint belt main body, an ankle restraint belt, a wrist restraint belt, and a data processing terminal; blood flow sensors, pressure sensors and temperature sensorsare embedded in inner walls of a neck restraint belt, shoulder restraint belts symmetrically disposed on both sides and waist restraint belts symmetrically disposed on both sides; and blood flow sensors, pressure sensors, and temperature sensors are embedded in the inner walls at two sides of the ankle restraint belt and inner walls at two sides of arms of the wrist restraint belt. Change data ofthe skin blood flow, the pressure and the temperature of a restraint part of a protective restraint patient can be calculated through the blood flow sensors, the pressure sensors, and the temperaturesensors; processing is performed by using a laser Doppler blood flow meter; data storage and analysis are performed by using a computer; and the protective restraint monitoring system effectively warns of the risk of pressure ulcers in long-term protective restraint parts and avoids complications.
Owner:NANJING BRAIN HOSPITAL
Non-invasive test system for peripheral vascular regulation function, and implementation method of non-invasive test system
PendingCN112674749AWill not introduce interferenceImprove accuracyBlood flow measurementTime domainBlood flow
The invention discloses a non-invasive test system for a peripheral vascular regulation function, and an implementation method of the non-invasive test system. The system comprises a temperature control module, a skin blood flow collection module, a blood flow signal analysis module and a vascular regulation function evaluation module; the temperature control module is used for inducing the skin of a to-be-tested object to generate a hyperemia reaction through temperature control; the skin blood flow collection module is used for collecting blood flow signals of the to-be-tested object before and after the hyperemia reaction; the blood flow signal analysis module is used for performing signal analysis on the blood flow signals acquired by the skin blood flow collection module and determining a time domain characteristic value and a frequency domain characteristic value of the blood flow; and the vascular regulation function evaluation module is used for determining a vascular overall regulation function evaluation index, a vascular endothelial regulation function index, a nerve regulation function evaluation index and a myogenic regulation function evaluation index according to the time domain characteristic value and the frequency domain characteristic value of the blood flow. The test process in the invention is free of trauma risk; the accuracy of a test result is improved; and the system can be widely applied to the technical field of medical instruments.
Owner:GUANGDONG PROV MEDICAL INSTR INST
A kind of detection method and application of human biological living body based on subcutaneous blood flow detection
ActiveCN103793690BEasy to implementImprove reliabilityCharacter and pattern recognitionPattern recognitionBlood flow
Owner:TIANJIN UNIV OF SCI & TECH
Photobiological measurement apparatus
Owner:SHIMADZU CORP
Application of ferulic acid in treatment of radioactive skin injury
PendingCN113559089AImprove protectionNon-irritatingOrganic active ingredientsAntipyreticInflammatory factorsNormal skin
The invention relates to a novel application of ferulic acid in treatment of radioactive skin injury, ferulic acid is prepared into a gel form, and the product has a good protection effect on cells and animal models damaged by <60> Co-gamma rays, has no stimulation effect on normal skin and can significantly enhance the oxidation resistance of HaCaT cells damaged by radiation. The ferulic acid gel is stable in physicochemical property, after the ferulic acid gel is used, the occurrence time of a skin wound is delayed, the red and swollen skin wound and the damaged area are reduced, and the skin blood flow at the wound is reduced than that of a non-medication group. The ferulic acid gel can inhibit activation of NLRP3 inflammasomes and reduce generation of inflammatory factors IL-18 and IL-1beta, so that inflammation is promoted to be relieved, injury edema is relieved, a good injury repairing effect on radioactive skin injury is achieved, and the technical effect of radiation resistance is achieved.
Owner:ACADEMY OF MILITARY MEDICAL SCI
Cosmetic composition for scrubbing
ActiveCN1921828AEasy to useUniform and excellent scrubbing effectCosmetic preparationsToilet preparationsStratum corneumBiomedical engineering
Provided is a cosmetic composition for scrubbing comprising scrub particles for increasing skin blood flow and removing a stratum corneum by being rubbed on the skin, wherein the scrub particles are bracken spores. When the cosmetic composition for scrubbing is rubbed on the skin, a plurality of polyps formed on surfaces of the bracken spores are broken, and thus, the cosmetic composition for scrubbing does not irritate the skin and has a good feeling of use and a uniform and excellent scrubbing effect.
Owner:LG HOUSEHOLD & HEALTH CARE LTD
Intelligent brake control system and control method based on emotion recognition
InactiveCN107089139BEasy to operateImprove reliabilityAutomatic initiationsSensorsIdentification systemMicroprocessor
Owner:XI AN JIAOTONG UNIV
Dual-mode imaging method and system for skin blood perfusion characterization
The invention discloses a dual-mode imaging method and system for skin blood perfusion characterization, which can be used for monitoring skin blood perfusion and solves the problems that in the prior art, when skin blood perfusion is monitored, skin blood flow velocity distribution and blood volume pulse waves cannot be obtained at the same time, and skin blood perfusion cannot be comprehensively evaluated. According to the dual-mode imaging method for skin blood perfusion characterization, two video imaging systems are adopted for synchronous control, blood volume and laser speckle video images are collected in real time and synchronously processed, blood flow velocity distribution and blood volume pulse waves are obtained at the same time, and real-time and comprehensive monitoring of blood perfusion of the skin to be detected is achieved. In order to achieve the method, the invention further provides a dual-mode imaging system for skin blood perfusion characterization, and the system comprises a laser light source, a collimation beam expander, a green light source, a beam splitter, a first optical filter, a first video imaging module, a second optical filter, a polaroid and a second video imaging module.
Owner:XI'AN INST OF OPTICS & FINE MECHANICS - CHINESE ACAD OF SCI
Cosmetic composition for scrubbing
Owner:LG HOUSEHOLD & HEALTH CARE LTD
Skin microvascular reactivity testing system and method based on local pressure induction
PendingCN114366044AAccurately reflect blood flow regulation abilityAvoid discomfortDiagnostics using lightBlood flow measurement devicesReactive hyperemiaBiomedicine
The invention discloses a skin microvascular reactivity test system and method based on local pressure induction, and provides a skin microvascular reactivity test system based on local pressure induction, a data acquisition module of the system comprises a pressure stimulation device and a skin blood flow detector, a pressure stimulation part and a blood flow detection part are kept consistent, the influence of other interference factors participating in adjustment is naturally shielded, the blood flow adjustment capacity of skin microvessels is accurately reflected, local pressure stimulation on a target position is achieved through the pressure stimulation device, large stimulation and discomfort caused to a tester can be avoided, and the test accuracy is improved. And inapplicable people such as hypertension and unstable vascular plaque patients do not exist. Under the condition that a tester is prevented from feeling uncomfortable, the blood flow characteristic signals are obtained through testing in the mode that reactive hyperemia is induced through local pressure, then the blood flow adjusting capacity of the skin microvessels can be evaluated, and the method can be widely applied to the technical field of biomedical engineering.
Owner:INST OF MEDICINE & HEALTH GUANGDONG ACAD OF SCI
Measuring method of skin blood perfusion
ActiveCN109662735BBlood flow measurement devicesInfrasonic diagnosticsHigh resolution imagingUltrasonic doppler
The technical solution of the present invention discloses a method for measuring skin blood perfusion, which combines the function of ultrasonic Doppler technology for fluid velocity measurement and the function of laser speckle technology for real-time monitoring of two-dimensional flow velocity. The actual speed directly reflects the amount of blood perfusion in the skin tissue. At the same time, the absolute value of blood perfusion can be directly measured; the two-dimensional real-time high-resolution imaging of skin blood perfusion can be realized; the value measured by the skin blood perfusion measurement method of the present invention can be used as a skin diagnosis. objective indicators.
Owner:亿慈(上海)智能科技有限公司
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