The invention relates to a 
radial basis function network multi-user detection method which is based on 
immunity dynamic adjustment, belonging to the field of 
wireless communication 
signal process technique; the 
radial basis function network multi-user detection method is characterized in that, known training data is sent at a gap of an emission part which is used for sending information 
source data packages; at the receiving part, the output weight values of a RBF multi-user 
detector are adjusted according to the training data, whether the 
user environment of CDMA 
system is changed or not is judged and whether the adjustment to the 
hidden layer parameters of the RBF multi-user 
detector is carried out continuously or not is determined; initial adjustment of the hidden 
layers of the RBF multi-user 
detector is carried out according to the sample points with big error in the training data; the 
hidden layer parameters of the RBF multi-user detector are adjusted by adopting an 
immunity optimization mechanism; RBF multi-user detector with best performance is selected as the result of the 
immunity dynamic adjustment. The detection method of the invention has strong adaptability for the channel changes in the CDMA 
system and the dynamic changes of the 
system environment such as user access-in, and achieves excellent 
detection performance and real-time performance.