A loc mechanism for a vehicle body frame of a through-road comprises a vehicle body frame and a butt joint frame As the core components of the whole locking mechanism, the vehicle body frame comprisea car body frame, a connecting rod, a car body frame sealing strip, a guide seat, a positioning pin, a handle, a base, a mounting bolt, a combined seal gasket and a car body fastener, and the car bodyframe is pre-fixed on the end surface of the car body through the car body fastener; The docking frame is formed to provide a fixed connection interface for the locking mechanism, and is located on the end face of the through channel, and comprises a docking frame, a rotating shaft, a fixed shaft, a push-pull handle and a docking frame sealing strip. 12 loc hooks and that rotate shaft on the buttjoint frame are driven to be matched or separated by pulling two handle, so that the through-way and the end face of the car body are quickly connected and unknitted, the operation is convenient andquick, and the maintenance efficiency of the through-way is improved.