The invention discloses an integrated pack-off and filling tool for sand control and well completion, which relates to the technical field of downhole operation tools for oil and gas wells, including an upper joint, a sealing assembly, a filling assembly and a lower joint, and also includes a backwashing assembly, a central pipe I, and an upper joint , backwash assembly, center pipe Ⅰ, filling assembly and lower joint are fixedly connected from top to bottom, and the sealing assembly is sleeved outside the center pipe Ⅰ; the backwash assembly is equipped with a return spring, which enhances the flexibility of backwash operations. Reliability; the filling component is equipped with a filter ring and an anti-erosion inner ring, which prolongs the service life of the integrated pack-off and fill tool; this device can be run in one trip without lifting the pipe string or running in other tools. Under normal circumstances, it can complete backwashing, setting, sealing, fracturing filling, circulating filling and production operations; compared with traditional operating tools, it can save more than half of the construction time and greatly reduce the construction cost.