79results about How to "Maintain concentration" patented technology

An electrical current generating system is disclosed that includes a fuel cell operating at a temperature of at least about 250° C. (for example, a molten carbonate fuel cell or a solid oxide fuel cell), a hydrogen gas separation system or oxygen gas delivery system that includes a compressor or pump, and a drive system for the compressor or pump that includes means for recovering energy from at least one of the hydrogen gas separation system, oxygen gas delivery system, or heat of the fuel cell. The drive system could be a gas turbine system. The hydrogen gas separation system or the oxygen gas delivery system may include a pressure swing adsorption module.

A pharmaceutical composition comprising a cyclosporin solid-state microemulsion is disclosed. In a preferred embodiment, the composition comprises a cyclosporin microemulsion dispersed in an enteric carrier. The composition does not dissolve in external phases such as artificial gastric fluid, but dissolves rapidly in artificial intestinal fluid, whereby it releases the cyclosporin microemulsion, providing rapid delivery of cyclosporin. The composition effectively maintains a therapeutic blood concentration of cyclosporin with once a day dosing, providing for convenience of administration and avoiding adverse effects induced by increasing peak blood cyclosporin concentrations associated with conventional cyclosporin formulations.

An anti-HIV agent containing, as an active ingredient, a 4-oxoquinoline compound represented by the following formula [I]

wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. The compound of the present invention has HIV integrase inhibitory action and is useful as an anti-HIV agent for the prophylaxis or therapy of AIDS. Moreover, by a combined use with other anti-HIV agents such as protease inhibitors, reverse transcriptase inhibitors and the like, the compound can become a more effective anti-HIV agent. Since the compound has high inhibitory activity specific for integrases, it can provide a safe pharmaceutical agent with a fewer side effects for human.

Methods and systems for performing continuous amplification of RNA and other nucleic acids are provided. Expression profiling using the continuous flow RNA amplification systems are also provided.

In a hand-free driving warning process for a vehicle, when a grip state of a steering wheel is in a hand-free driving state, and the vehicle is in a travel state stipulated previously, a danger degree is derived based on a position of a vehicle compartment where a non-grip hand exists. In deriving the danger degree, when the non-grip hand is in a high danger position, a high level is set; when the non-grip hand exists in a low danger position, a middle level or a low lever is set. In the low level, any warning is not outputted; in the middle level, a warning is outputted in a sound volume smaller than a usual sound volume; and in the high level, a warning is outputted in the usual sound volume or greater.

The present invention relates to a compound represented by the following formula [I]

wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof, or a solvate thereof, and a pharmaceutical composition, an anti-HIV agent and an HIV integrase inhibitor containing such compound. The compound of the present invention has an HIV integrase inhibitory activity, and is useful as an anti-HIV agent, or as an agent for the prophylaxis or treatment of AIDS. In addition, by the combined use with other anti-HIV agents such as a protease inhibitor, a reverse transcriptase inhibitor and the like, it can be a more effective anti-HIV agent. Because it shows integrase-specific high inhibitory activity, the compound can be a pharmaceutical agent safe on human body, which causes only a fewer side effects.

A method, apparatus, and system for obtaining a solution from a solid product are disclosed. A solid product is housed in a dispenser. A liquid is introduced into the housing of the dispenser to interact with the solid product to form a solution. To control the concentration of the formed solution, the turbulence of the liquid introduced to the dispenser is controlled and adjusted either manually or on a real time basis to account for varying characteristics of either or both of the solid product and the liquid. The dispenser will adjust the turbulence based on the characteristics to maintain a formed solution within an acceptable range of concentration. The concentrated solution can then be discharged from the dispenser to an end use application.

The present invention provides a transdermal drug delivery system comprising donepezil or its pharmaceutically acceptable salt and method of making the same.

Provided is a compound represented by the formula (1):

wherein R¹ and R² are each independently a hydrogen atom or a straight chain alkyl group having a carbon number of 1-3, R³ is a hydrogen atom, an alkyl group having a carbon number of 1-4, an alkoxyalkyl group, an aryl group, a halogen atom or a haloalkyl group, or a pharmaceutically acceptable salt thereof, which has, unlike known PGI₂ analogs, a selective EP4 agonist action, and a medicament containing the compound, which is useful for the prophylaxis and/or treatment of immune diseases, diseases of the digestive tract, cardiovascular diseases, cardiac diseases, respiratory diseases, neurological diseases, ophthalmic diseases, renal diseases, hepatic diseases, bone diseases, skin diseases and the like.

The present invention discloses a whipping unsalted cream and a production process thereof, the stirred unsalted butter of the invention contains the following components in 100g of raw material: 80 to 98g of unsalted butter, 0. 5 to 19g of milk, 0. 1 to 0. 8g of emulsifier, 0. 1 to 0. 8g of stabilizer, 0. 0 to 0. 1g of pigment, 0. 0 to 0. 05g of preservative and balance of water, preferably, nutrition enhancer is added. The production process includes the following steps of raw milk acceptance, the separation of unsalted butter, the addition of milk, emulsifier, stabilizing agent, pigment and preservative, pasteurization, UHT sterilization, homogenization, cooling, on line addition of nutrition enhancer in sterile environment and packaging. The product of the invention has smooth taste, high whipped topping, rich nutrient and long collapse period, and the shelf life is prolonged by the adoption of UHT sterilization and aseptic package and on line addition of nutrition energizing agent.

It is intended to provide a preparation for percutaneous administration of 2-(4-ethyl-1-piperazinyl)-4-(4-fluoro-phenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine (Compound A), which inhibits the generation of a metabolite and is capable of continuously maintaining a blood drug level. Specifically, a tape preparation comprising an adhesive layer formed on one surface of a support, characterized in that the adhesive layer contains (1) Compound A or a physiologically acceptable acid addition salt thereof, and (2) an acrylic adhesive, or (1) Compound A or a physiologically acceptable acid addition salt thereof, (2) an acrylic adhesive, and (3) a permeation enhancer is provided.

The invention discloses a field weeding method for the organic cultivation of paddy rice. The method comprises the steps of preparing soil, nursing seedlings, transplanting, applying fertilizer, managing water and fertilizer, and applying organic manure before the transplanting of rice seedlings, i.e. forming a surface restoration layer; after the transplanting of the rice seedlings, applying biogas slurry to form a 4-5cm biogas water layer; and by the adoption of sparse seeding, earlier-stage promotion and later-stage control, implementing watering and fertilization at the two-leave one-heart stage, and controlling fertilizer and water at the later stage. From the point of ecology, the method realizes the purpose of preventing and eradicating field weeds by organically combining the application of the biogas slurry and the organic manure according to the biological characteristics of the paddy field weeds and the paddy rice, and has the advantages of ecosystem, environmental protection and the like as a paddy field weeding method which is good in weeding effect, cost-saving, yield-enhancing, effect-enhancing, simple and easy, thereby having important significances to the organic production of paddy rice in China.

The present invention provides a transdermal drug delivery system comprising a drug-containing matrix layer comprising: (a) donepezil or a pharmaceutically acceptable salt thereof as an active ingredient; and (b) an acrylate-rubber hybrid as an adhesive.

A controlled-release pharmaceutical composition including first and second groups of microparticles, each of the microparticles including a core including tamsulosin or pharmaceutically acceptable salts thereof, a controlled-release polymer coating layer formed on the core, and an enteric polymer outer layer formed on the controlled-release polymer coating layer, wherein the average thickness of the controlled-release polymer coating layer is different in each of the first and second groups of microparticles, and an oral formulation including the same, are provided. This pharmaceutical composition can easily control the extent of release of an active ingredient depending on changes in pH in the intestinal tract and the release pattern of the active ingredient in the small intestine, thus preventing the active ingredient from being rapidly transferred into the blood to thereby minimize side-effects, and maintaining the effective blood concentration of the active ingredient for a predetermined period of time. Furthermore, this composition can shield the bitter taste of the active ingredient even when exposed to the inside of the mouth, thus increasing the therapeutic effects for patients upon oral administration.

The embodiment of the invention discloses a barrage display method and device, a storage medium and a terminal. The method comprises the steps: receiving a triggering instruction, transmitted by a second terminal, of a gesture barrage, and collecting an input gesture image; recognizing a target gesture corresponding to the gesture image, and determining gesture information corresponding to the target gesture; sending the gesture information to the second terminal; and receiving a target barrage corresponding to the gesture information sent by the second terminal, and displaying the target barrage. By adopting the embodiment of the invention, the user concentration can be maintained.

The invention relates to the technical field of energy sources, in particular to an alcohol production method and device by means of fermentation-membrane separation coupling. Microorganisms are mainly adopted for biological fermentation, and the membrane separation technology is combined for alcohol preparation. According to the alcohol production method, the fermentation-membrane separation technology is coupled, the inhibitory effect of product alcohol on fermentation in the fermentation process can be solved, and the activity and concentration of the microorganisms in a fermentation tank are maintained, so that the continuity of biological fermentation is achieved; high-purity protein can be obtained and can be applicable to feed; in the production process, waste water can be comprehensively treated.

The invention provides a processing method for an automatic dosing system. The processing method for the automatic dosing system includes the steps that a liquid level control device in an oil tank of each machining machine is used for sensing the height of cutting fluid, when the height of the cutting fluid is in a low level state, the automatic dosing system is controlled to use pumps in cooperation with electromagnetic valves to transport the cutting fluid in the oil tanks into oil storage barrels respectively through oil pumping pipelines, and a medicine preparing barrel uses the pumps in cooperation with the electromagnetic valves to transport water and agentia into the oil storage barrels respectively through a medicine preparing pipeline according to the set time, the cutting fluid with preset concentration can be prepared in sequence in a circulating mode, and the oil storage barrels use the pumps in cooperation with the electromagnetic valves to transport the prepared cutting fluid with the preset concentration into the oil tanks to refuel through a refueling pipeline. The automatic dosing system can automatically refuel the oil tank of each machining machine, working hours and cost of manpower detection and refueling can be effectively saved, and the concentration of the cutting fluid in the oil tanks can be maintained, so that the machining precision of workpieces can be improved, and the service life of cutting tools can be prolonged.

The present invention provides a transdermal drug delivery system comprising fentanyl or its pharmaceutically acceptable salt and method of making the same.

An anti-explosion ceiling lamp structure comprises a casing, two bosses, a front cover, a transparent cover and connection pieces. The casing is a barrel body with one end open and comprises the opening end. The two bosses are arranged abreast on the peripheral edge of the opening end, a gap is formed between the two bosses, and a strip hole is formed in each boss and stretches in the axial direction of the casing. The front cover is detachably connected onto the opening end, a protrusion is arranged on the outer peripheral wall of the front cover, and a connection hole is formed in the protrusion. The transparent cover is arranged on the front cover and is connected with the casing through the front cover, the protrusion is located between the two bosses, the connection pieces penetrate the strip holes and the connection hole, the connection pieces can slide in the strip holes to enable the front cover to be connected with the bosses through the connection pieces. During maintaining of the anti-explosion ceiling lamp, the front cover, the transparent cover and the like are hung on the bosses through the connection pieces, an opening between the front cover and the casing is large, and the maintaining is convenient.

A controlled-release pharmaceutical composition including first and second groups of microparticles, each of the microparticles including a core including tamsulosin or pharmaceutically acceptable salts thereof, a controlled-release polymer coating layer formed on the core, and an enteric polymer outer layer formed on the controlled-release polymer coating layer, wherein the average thickness of the controlled-release polymer coating layer is different in each of the first and second groups of microparticles, and an oral formulation including the same, are provided. This pharmaceutical composition can easily control the extent of release of an active ingredient depending on changes in pH in the intestinal tract and the release pattern of the active ingredient in the small intestine, thus preventing the active ingredient from being rapidly transferred into the blood to thereby minimize side-effects, and maintaining the effective blood concentration of the active ingredient for a predetermined period of time. Furthermore, this composition can shield the bitter taste of the active ingredient even when exposed to the inside of the mouth, thus increasing the therapeutic effects for patients upon oral administration.

The fumigating type integrated medication and heat-therapeutic bed comprises bed, medicine box, water pump, electric heater, fan, radiator and pipeline. Its mattress is made up by high-foam sponge, the undersurface of the medicine box is connected with a three-way piece whose one end is connected with inlet of water pump through pipeline, the outlet of water pump is connected with heater via pipeline. Said heater can have three layers of insulating layer, its outlet is connected to a dialysis pipe which is made up by using conventional dialysis material and is connected with radiator. Under the radiator a fan is set, the water pump makes the medicine in the medicine box flow into heater and applies pressure to medicine, the medicine is heated and flowed into dialysis pipe and released into a closed shell body, then the medicine gas is heated and pressurized, and passed through the mattress to act on human body.

The invention discloses a medical dressing device which is characterized by comprising three parts, including an outer sleeve (1), a housing (2) and an inner core (3), for wrapping in sequence, wherein the outer sleeve is formed by superimposing three layers of medical gauzes, the housing (2) is made of an elastic material, the inner core (3) is made of sponge, and a plurality of through holes (4) are formed in the housing (2). By using the medical dressing device provided by the invention, a liquor can be infused into the inner core and then permeates into the outer sleeve through the through holes, and then acts on an affected part, a wet dressing effect is played and the humidity and the concentration are kept, safety and reliability are ensured, the manufacturing is easy, and the medical dressing device has good economic value and medical value.

The present invention relates to a sustained-release tablet containing doxazosin mesylate, and more particularly to a sustained-release tablet of which drug release rate maintains constant for 8 hours and longer.

The present invention provides a combined drug for an injectable depot formulation having a superior effect of preventing and/or treating polycystic kidney disease. More specifically, the present invention relates to a drug for preventing and/or treating polycystic kidney disease, which is an injectable depot formulation comprising a particle containing tolvaptan or a prodrug thereof and a somatostatin analogue. The present invention also relates to a method for preventing and/or treating polycystic kidney disease using the drug.