The invention relates to the technical field of separation of medicinal materials, in particular to an automatic medicinal material unpacking device. The device comprises a supporting mechanism, a gripping mechanism, a lifting mechanism, a walking mechanism and a cutting mechanism; the supporting mechanism comprises a bracket, a first material storage bin and a second material storage bin which are formed by the bracket in sequence, wherein the first material storage bin is used for storing bundled medicinal materials, the second material storage bin is used for storing unfastened medicinal materials, and the first material storage bin is communicated with the second material storage bin; the walking mechanism comprises a slide rail and a driving vehicle, and the driving vehicle is slidably connected to the slide rail; the cutting mechanism comprises cutters; the cutting mechanism is arranged in the second material storage bin, the slide rail extends into the second material storage bin from the first material storage bin and is fixedly connected to the upper portion of the bracket, one end of the lifting mechanism is connected with the driving vehicle, and the other end of the lifting mechanism is connected with the gripping mechanism. Through the arrangement of the gripping mechanism, the lifting mechanism, the walking mechanism and the cutting mechanism, cutting of medicinalmaterial packages is automatically completed at a time, the labor intensity of workers is greatly reduced, and the production efficiency of the whole production line is improved.