The invention discloses a medical operating room air sterilization device. The medical operating room air sterilization device comprises two box bodies; one side of each box body facing the other boxbody is uniformly provided with blow holes. In applications, the two box bodies are arranged on the left side and the right side in an operating room, an operating table is arranged between the two box bodies, antiskid plates are unfolded, fastening rotary knobs are unfastened, expansion boxes are pulled out using handles, the blow holes are aligned, electricity is provided, ultraviolet lamps andan exhaust fan are turned on; the ultraviolet lamps are arranged in a staggered manner in a sterilization pipe from top to bottom, so that the fluidity of gas flow is ensured, sterilization effect isimproved, entering of pumped in gas into the right side box body is realized, the box body area is relatively low, moving towards the left is carried out, blowing onto the left side box body is realized, the left box body is driven by a gas-guide tube for gas suction of the right end surface, air moves in a whole surface, air residue is reduced, comprehensive air replacement is ensured, sterilization is more complete, and effects are better.