The utility model relates to the technical field of transmission cabinets, and discloses a transmission cabinet for network and information safety management, which comprises a transmission cabinet body and a fixing frame, a mounting plate is fixedly mounted on the outer surface of the fixing frame, and a mounting frame is fixedly mounted on one side, far away from the fixing frame, of the mounting plate. A sliding groove and a first through hole are formed in the outer surface of the mounting frame. According to the transmission cabinet for network and information safety management, through cooperation of the sliding blocks, the sliding grooves, the limiting rods, the first through holes and the second through holes, rapid installation of the laminates can be achieved, through the design of the multiple first through holes, the distance between the adjacent laminates can be conveniently adjusted, related equipment of different sizes can be conveniently placed, the transmission cabinet is suitable for different working conditions, the adaptability is high, and the practicability is high. And through the design of the dustproof net, dust in air is prevented from entering the transmission cabinet body through the ventilation opening, the dust is prevented from being accumulated in the transmission cabinet body after long-time use, the overall heat dissipation performance is influenced, and the practicability is high.