25 results about "Isotopic ratio" patented technology

The invention discloses a device and a detection method for online oxidation-enrichment-reduction determination of nanogram-level nitrogen isotopes in a solid, and belongs to the technical field of nitrogen isotope analysis. The device comprises an oxidation system, a nitrogen oxide enrichment system, a nitrogen reduction system, a mass spectrum interface system, a stable isotope ratio mass spectrometer and pipelines for connecting all parts of the device. The device provided by the invention greatly reduces the quantitation limit of the nitrogen isotope in the solid sample, can realize high-precision determination of the nanogram-level nitrogen isotope in the solid sample, and has the advantages of simplicity and convenience in operation, high accuracy and the like.

The application belongs to the technical field of chemical detection, and particularly relates to a Raman-LIBS-mass spectrometry combined analysis device and analysis method. The Raman-LIBS-mass spectrometry combined analysis device comprises a multiple-reflection time-of-flight mass spectrometer, a LIBS spectrometer, a Raman spectrometer and a shared module. The shared module comprises a first incident light path system, a second incident light path system, a high-definition observation system, a vacuum sample bin, a vacuum system and a control system. The first incident light path system is used for generating a femtosecond laser beam and performing three-dimensional ablation on a sample. The second incident light path system is used for combining tunable lasers into a resonance ionization light path. Compared with the prior art, the application can realize in-situ micro-area ultra-high resolution element and isotope analysis and imaging, realize ultra-trace element, isotope analysis and isotope ratio analysis under strong matrix interference, and can also perform high-resolution molecular structure and composition analysis and Raman scattering imaging.

The application discloses a kind of gas isotopic ratio measurement system and method, it relates to gas isotopic measurement technical field, in the system, double-layer sealed panning gauge is used to obtain the mixed gas to be measured, after energization, make the mixed gas to be measured occur panning discharge, produce the light signal containing each isotopic characteristic spectrum;Double-layer sealed panning gauge includes gauge tube, coaxially arranged inner layer sealing structure and outer layer sealing structure;Lens group is used to collect and focus light signal;Optical fiber is used for remote transmission light signal collected by lens group;Spectrometer is used for the light signal transmitted by optical fiber is spectrally resolved, forms the spectrum according to wavelength development;Photoelectric detector is used to convert spectrum into electrical signal;Computer is used to determine the proportion of each isotopes in the mixed gas to be measured according to electrical signal.The application realizes redundancy protection by double-layer sealing structure, ensures that discharge condition is stable under harsh environment, prevents gas leakage, realizes high-precision and safe measurement of gas isotopic ratio under high-risk scene.

The application discloses a marine organism fossil U-Pb dating method based on LA-ICP-MS, and comprises the following steps: S1, according to stratigraphic division, marine organism fossils and iron manganese oxides of each layer are selected from a deep sea sediment column, and the rest is taken as a sediment residue; S2, the marine organism fossils are cleaned, and marine organism fossil target samples are prepared; S3, a laser ablation inductively coupled plasma mass spectrometer is used to perform laser ablation, point marking, sequencing and testing on the marine organism fossil target samples, and uranium lead isotope data is obtained; S4, baseline deduction and mapping are performed on the uranium lead isotope data, the lead isotope ratio of the sediment residue is anchored as an initial value to perform ordinary lead correction, and the age data of the marine organism fossils is obtained; the laser ablation mode is a line scanning mode. The marine organism fossil U-Pb dating method realizes dating test of marine organism fossils, and has high determination accuracy.

A pharmaceutical composition for isotope-selective modulation including at least one isotope selected from the group consisting of 1H, 6Li, 12C, 10B, 14N, 16O, 17O, 24Mg, 26Mg, 28Si, 29Si, 32S, 33S, 39K, 35Cl, 40Ca, 42Ca, 43Ca, 50V, 50Cr, 52Cr, 54Fe, 56Fe, 58Ni, 60Ni, 61Ni, 63Cu, 64Zn, 66Zn, 92Mo, 94Mo, 95Mo, 96Mo, 74Se, 76Se, 77Se, 78Se, 70Ge, 72Ge, 73Ge, 79Br, 85Rb, 107Ag, 130Ba, 132Ba, 134Ba, 135Ba, and 136Ba, wherein said at least one selected isotope is enriched to exceed its relative isotopic ratio found in a naturally occurring sample of the same chemical element. Methods for its use include investigating the isotopic signatures, intervening with isotopic fractionation in mammals.

The invention belongs to the technical field of shale oil and gas development, and discloses a shale oil-gas-bearing potential multi-parameter collaborative evaluation method. The method integrates six experimental technologies of nitrogen adsorption, carbon dioxide adsorption, carbon and oxygen isotope, rock pyrolysis and XRD total rock / clay analysis, and comprises the core steps of obtaining multi-dimensional data such as a pore structure, mineral composition, organic matter characteristics, an isotope ratio and the like after standardized pretreatment of a shale sample, and performing parameter correction, weight distribution and collaborative modeling to obtain a shale sample. And quantifying the oil-gas potential index and grading. The method solves the problem that traditional single parameter evaluation is insufficient in accuracy, data are comprehensive and reliable, and key technical support is provided for shale oil and gas exploration and development and reservoir evaluation.

The invention provides an experimental method for determining stable carbon and oxygen isotopes by a two-way sampling method, and relates to the technical field of stable isotope analysis. The experimental method comprises the following steps: selecting carbon dioxide gas with the purity of more than 99.999% as carbon dioxide reference gas, and selecting a calcium carbonate carbon and oxygen isotope standard substance and a target sample to be measured; and then the stable carbon and oxygen isotopes are determined through a two-way sample introduction method, standard gas does not need to be purchased, the isotope ratio of a sample relative to a standard substance is obtained through conversion application of a formula, finally, the isotope ratio is successfully calibrated to the value of international standard PDB, and the experiment cost is saved. The method can be widely applied to other stable isotope two-way sample introduction methods, principle communication is achieved, and determination can be conducted through the experimental method under the condition that no standard gas exists.

The invention discloses a carbon sequestration area determination method and device, a storage medium and an electronic device, and the method comprises the steps: carrying out the component analysis of underground water data of different geological stratums in a candidate sequestration area, and obtaining the isotope ratio of the same chemical composition, the isotope ratios are generated from chemical compositions and isotopes of the chemical compositions in the groundwater data, the different geological stratums include overground cover stratums and underground reservoirs, and the isotope ratios include a first isotope ratio of the overground cover stratums and a second isotope ratio of the underground reservoirs; according to the ratio change value of the first isotope ratio and the ratio change value of the second isotope ratio, determining the sealing grade of the candidate sealing region; and determining the candidate sequestration area as a carbon sequestration area under the condition that the closure level is determined to be higher than the preset level. By adopting the technical scheme, the problem that the storage area cannot be accurately determined is solved.

The present invention may be applied to a measuring device capable of measuring a concentration ratio between carbon isotopes in carbon dioxide. One embodiment of the present invention comprises: a light source unit; a sample gas cell which is positioned on an optical path irradiated from the light source unit; a gas cell band-pass filter unit which is positioned on the optical path which has passed through the sample gas cell, and is provided with a first band-pass filter and a second band-pass filter, the first band-pass filter having formed therein a sealed space in which a gas containing a first isotope is present, and the second band-pass filter having formed therein a sealed space in which a gas containing a second isotope, which is a different isotope of the same element as that of the first isotope, is present; and a light receiving unit.

This invention relates to the field of analytical chemistry, and more particularly to an analytical method for determining the hafnium content in nuclear-grade zirconium alloys. The analytical method includes the following steps: Step S2: Dissolving a metallic or oxide hafnium isotope in concentrated hydrochloric acid and concentrated hydrofluoric acid to prepare an isotope diluent stock solution; Step S2: Adding a corresponding hafnium single-element standard solution to the isotope diluent stock solution, determining the isotope ratio R value, and calibrating the concentration of the diluent solution; Adding the calibrated isotope diluent solution to the zirconium alloy, dissolving the zirconium alloy sample in concentrated hydrochloric acid and concentrated hydrofluoric acid to obtain a sample solution to be separated; Performing extraction chromatography on the sample solution to obtain a hafnium-containing test solution; Determining the hafnium content in the hafnium-containing test solution using inductively coupled plasma mass spectrometry. This invention can accurately determine the hafnium content in nuclear-grade zirconium alloys, improving the stability and accuracy of the analytical results.

According to the rubidium isotope proportion measuring device and method based on the nuclear spin slowing factor, two beams of orthogonal laser are driven through an automatic upper computer, magnetic resonance frequencies of a high-temperature alkali metal air chamber in different bias magnetic fields are searched under different optical powers, the gyromagnetic ratio is calculated through linear fitting, and therefore the nuclear spin slowing factor of an atom ensemble is obtained, and the rubidium isotope proportion measuring method based on the nuclear spin slowing factor is obtained. And solving an overdetermined equation set by using the relationship between the slowdown factor and the isotope proportion and the rubidium atom isotope proportion, thereby realizing accurate measurement of the rubidium atom gas chamber gas isotope proportion. Compared with a conventional method, the device and the method have the advantages of accuracy, rapidness, simplicity and lower cost, and the closed air chamber structure does not need to be damaged.

The application discloses a kind of double-beam LAAS isotopic ratio high-precision fast measuring device and method, the device includes: second light splitting piece is used to first tunable laser light, after splitting, a small part enters first photoelectric detector, most enters first polarized beam splitter prism;Third light splitting piece is used to second tunable laser light after passing through second reflector, after splitting, a small part enters second photoelectric detector, most enters first polarized beam splitter prism;First photoelectric detector and second photoelectric detector are used to measure the intensity of first tunable laser light and second tunable laser light entering it respectively;Third photoelectric detector and fourth photoelectric detector are used to measure the intensity of first tunable laser light and second tunable laser light entering it respectively.The application greatly improves isotopic ratio measurement precision, and without laser wavelength scanning, without calibration, it can realize fast direct measurement to isotopic ratio.

This invention discloses an isotope tracing monitoring device and method for flue gas thermal fracturing-displacement-sealage, belonging to the field of isotope tracing technology. It includes multiple combined extraction and monitoring wells and multiple L-shaped injection wells. The vertical portion of each injection well and the combined extraction and monitoring wells penetrate the rock strata from top to bottom and extend into the coal seam, while the horizontal portion of the injection wells is within the coal seam. This invention utilizes separate injection... 13 CO2, 15 NO2 34 SO2, acting as a "fingerprint marker," combined with online isotope ratio analysis, enables independent, in-situ, and simultaneous tracking of key pollutant components in flue gas. Based on an isotope mass balance model, the real-time retention rate and cumulative sequestration amount of CO2, SO2, and NO2 can be calculated separately and quantitatively. This overcomes the limitations of traditional technologies that can only assess the overall sequestration effect, providing a revolutionary means for accurately assessing the sequestration safety and environmental risks of different pollutants.

This invention discloses a method for determining the phosphate oxygen isotopes of a single dentomorph based on ion chromatography-electrostatic orbital trap mass spectrometry, belonging to the field of isotope geochemical analysis technology. The method includes: acid digestion step; lyophilization step; reconstitution step; ion chromatography separation and fraction collection step; mass spectrometry analysis step: acquiring the mass spectrometric signals of the target fragment ions; isotope ratio calculation step: calculating the oxygen isotope shift of the sample relative to the reference solution; and calibration step: establishing a calibration curve using multiple known phosphate reference materials to obtain the phosphate oxygen isotope composition of the sample. This invention simultaneously solves three technical bottlenecks in existing thermal conversion elemental analysis-isotope ratio mass spectrometry methods: high sample consumption and cumbersome procedures prone to fractionation; secondary ion mass spectrometry methods: mixed signals and inability to distinguish different oxygen-containing components; and pure solution electrostatic orbital trap mass spectrometry methods: lack of solid sample pretreatment support.

A pharmaceutical composition is used for improving health, curing abnormalities and degenerative diseases, and achieving anti-aging therapeutic effect in mammals. The pharmaceutical composition includes a pharmaceutical carrier and an isotope selective component including at least one of a chemical element in which the isotopic ratio of at least one light isotope is altered to exceed natural abundance.

The invention discloses an in-situ micro-area beryl Rb-Sr dating correction method which comprises the following steps: 1, after a selective reaction active gas reacts with Sr, calculating an 86Sr signal by using a signal of a product, so as to improve the accuracy of a Sr element signal; 2, correcting the ratio of 87Rb / 87Sr and the ratio of 86Sr / 87Sr by adopting a glass standard substance with a uniform Rb / Sr isotope ratio; the method comprises the following steps of: drawing an inverse isochrone graph by adopting a substrate-matched beryl standard substance HJLG241 or XXG251, calculating an apparent age, calculating a substrate effect deviation coefficient according to the apparent age and a recommended age, and applying the coefficient to 86Sr / 87Sr ratio correction of an unknown sample. According to the method, accurate dating of the in-situ micro-area beryl Rb-Sr is realized, accurate dating of the laser micro-area beryl Rb-Sr is realized, and the method has the advantages of high spatial resolution, high dating success rate, short test period and the like.

The present invention relates to a method for early diagnosis of a possible disease state in a patient suspected of having prostate cancer. The present invention provides a method for determining the isotope ratio or isotope quantity ratio of calcium isotopes in a blood sample of a patient suspected of having prostate cancer, the method comprising the steps of: i. determining the isotope ratio or isotope quantity ratio of calcium isotopes in a blood sample of a patient suspected of having prostate cancer; ii. determining the isotope ratio or isotope quantity ratio of calcium isotopes in a range defined by the value determined in step i and a threshold value; 44 / 42 Ca 血清 iii. based on the comparison of step ii, assigning the value to one of three states M0, M1, and M2 defined below, where M0: -0.91‰<δ 44 / 42 Ca 血清 Value<-0.79‰ M1:δ 44 / 42 Ca 血清 Value<-0.91‰ M2:δ 44 / 42 Ca 血清 Including values ​​> -0.79‰.

A failed fuel pin releases cesium into the primary sodium coolant and xenon into the cover gas in the reactor vessel. A tube containing radioactive liquid sodium receives the flowing primary sodium from the reactor vessel. A radiation detector is positioned near the tube to measure gamma rays emitted from the tube. The tube may be isolated to increase the detection limit by allowing short-lived isotopes to decay. Isotope ratio 137 Cs / 134 Cs can be measured and used to determine the burnup of the fuel assemblies from within the reactor core. As a result, failed fuel assemblies can be identified based, at least in part, on their burnup. Additionally, mass spectrometry may be used to measure the ratio of stable to unstable xenon isotopes. These identification techniques may be used in combination to rapidly identify failed fuel assemblies in situ during reactor operation.

The invention discloses a method for measuring the content of 227Ac in a 225Ac solution, and belongs to the technical field of nuclide analysis. Comprising the following steps: providing a 227Ac diluent solution with known activity concentration; equally dividing a to-be-detected 225Ac solution into two equal parts, adding a quantitative 227Ac diluent solution into one part as a labeled sample, and taking the other part as a non-labeled sample; respectively measuring the isotope ratios of 227Ac / 225Ac in the two samples; based on the principle of isotope dilution mass spectrometry, by comparing two ratios and combining the sampling amount, the diluent solution adding amount and the activity concentration of the diluent solution, a material balance relation is constructed, and the activity concentration of 227Ac and 225Ac in the to-be-detected solution is obtained. According to the invention, absolute measurement is realized through the principles of high-sensitivity measurement, micro-sampling and an isotope dilution method of a mass spectrometer; and by combining a material balance equation, the method for rapidly and accurately measuring the content of 227Ac in the 225Ac solution in a trace amount can be realized.

The application discloses a method for determining the hydrothermal activity age of a volcanic rock reservoir, and relates to the technical field of volcanic rock identification. The method comprises the following steps: obtaining a zircon sample target of the volcanic rock reservoir to be measured; performing laser Raman spectrum testing to obtain Raman spectrum data of the zircon sample target; processing the data to obtain the peak position and half-height width of the vibration peak v3SiO4 of the zircon sample target; fitting the half-height width and the position parameter of the wave peak center of the vibration peak v3SiO4 to determine the morphological characteristics and composition of the inclusion in the zircon; performing isotopic proportion and trace element composition analysis to determine the formation age of the zircon; and constructing a half-height width-time fitting curve to determine the formation period of the hydrothermal mineral coexisting with the zircon. The method can be used to divide the zircon period of the volcanic lava, and has a good determination on the zircon genesis, thereby providing an important identification basis for the late hydrothermal / tectonic action events and time of the volcanic rock reservoir.

The invention discloses a method for tracing the hydrothermal activity of a sedimentary basin, and belongs to the technical field of geochemistry and isotopic tracing. The tracing method comprises the following steps: pre-treating a mixed mineral sample, separating and purifying a lithium element, and measuring a delta 7 Licarb value; carrying out correlation analysis on the delta 7 Licarb value and the main trace element characteristics of the sample; correcting the measured delta 7 Licarb value of the mixed mineral sample; performing correlation analysis on the corrected data of the mixed mineral sample, a hydrothermal activity index and an anti-weathering index; and determining a corrected background value of delta 7Li in the research sequence, and judging a hydrothermal activity enhancement period, a hydrothermal activity weakening period or a non-hydrothermal dominant period by comparing a difference between a lithium isotope ratio of a continuous layer section and a background interval value. The method has the advantages of continuous high resolution, wide temperature range sensitive response, clear mechanism, strong anti-interference capability and strong universality.

The application discloses a kind of sedimentary basin hydrothermal activity tracer method, belong to geochemistry and isotopic tracer field.The tracer method includes the pretreatment of mixed mineral sample, lithium element separation and purification and δ 7 Li carb Value determination;The correlation analysis of δ 7 Li carb Value and the main trace element characteristics of sample;The measurement δ 7 Li carb Value of mixed mineral sample is corrected: the correlation analysis of corrected data of mixed mineral sample and hydrothermal activity index and anti weathering index;Determine the δ 7 Li 校正后 Background value in study sequence, judge hydrothermal activity enhancement period, hydrothermal activity weakening period or non-hydrothermal dominant period by comparing lithium isotopic ratio of continuous section and background interval value difference.The method has the advantages of continuous high resolution, wide temperature range sensitive response, mechanism is clear, strong anti-interference ability and strong universality.

This invention discloses a method for analyzing heavy metal pollution sources in groundwater based on characteristic ion screening. This method utilizes multi-media collaborative sampling to determine the concentration of heavy metals in groundwater, the content of BCR speciation in sediments, and the isotopic ratios of lead, zinc, and copper. Characteristic ion combinations are extracted through a three-level screening process using enrichment factors, ion ratio variation coefficients, and Pearson correlation. Three types of fingerprint vectors—water chemistry, solid phase speciation, and isotopic composition—are normalized and fused, and candidate pollution sources are matched using cosine similarity. With mass conservation as the primary likelihood and BCR speciation and isotopic mass balance as additional constraints, the spatial distribution field and high-risk areas are obtained through Kriging interpolation using the posterior mean of the MCMC output contribution rate and a 95% confidence interval. This invention can identify four types of pollution sources, reducing reconstruction error by 73% compared to the PMF method, compressing the confidence interval width by 65%–73%, and achieving a field compliance rate of 92%, providing quantitative evidence for pollution prevention and control and accountability.