The invention discloses a chest model capable of being used for percutaneous pulmonary nodule puncture under CT imaging guidance, which comprises a simulated human chest model and a pulmonary nodule model, the simulated human chest model is provided with skin, fat, muscle tissue, pleural membrane and lung tissue in a simulated manner from outside to inside, the simulated human chest model is internally provided with a cardiovascular system and a skeleton system in a simulated manner, the pulmonary nodule model is embedded in lung tissue, a training doctor can carry out whole-course, full-simulation, repeated and multi-part needle biopsy training of CT-guided percutaneous paracentesis with the model, the practical ability of the needle biopsy is rapidly improved, the basic operation skill of the CT-guided percutaneous pulmonary nodule paracentesis is mastered skillfully, the success rate is increased, the risk is reduced, the medical level is improved, the problem of practical training of CT-guided percutaneous puncture biopsy in various hospitals at present is solved, the medical safety is guaranteed, the medical diagnosis and treatment level is promoted, and the CT-guided percutaneous puncture biopsy model is scientific, practical and suitable for standardized promotion and popularization of CT-guided percutaneous puncture.