The invention discloses a non-steroidal anti-inflammatory
drug suspension drop and a preparation method thereof. The suspension drop comprises
ibuprofen,
xanthan gum,
pregelatinized starch, glycerin,
sucrose,
anhydrous citric acid,
sodium benzoate,
polysorbate 80, strawberry essence and water. The preparation method comprises the following steps: 1) sieving
ibuprofen with a 20-mesh
sieve for later use; the preparation method comprises the following steps: adding
polysorbate 80 into
purified water, stirring and dissolving, adding
ibuprofen according to the prescription amount, and stirring and dispersing uniformly; 2) adding 100 DEG C
purified water and
glycerol into the liquid preparation tank, and stirring and mixing; (3) starting a rotor pump and a homogenizing pump to form internal circulation in the liquid preparation tank, opening a
ball valve of a charging hopper, adding
xanthan gum and
pregelatinized starch, closing the valve of the hopper, and homogenizing and stirring until the step (6) is finished; (4) weighing
cane sugar, adding the
cane sugar into boiling water at 100 DEG C, and stirring for dissolving; 5) continuously stirring in the liquid preparation tank, adding a
sucrose solution, washing the container with water, and adding into the liquid preparation tank; 6) adding
anhydrous citric acid and
sodium benzoate into the liquid preparation tank, and stirring for more than 1 hour after the steps 3-6 are finished; 7) closing the homogenizing pump, adding an ibuprofen dispersion liquid into the liquid preparation tank, washing the dispersion container with water for several times, and stirring; (8) adding essence into the liquid preparation tank, and stirring; 9) adding the total amount of
purified water, and stirring; and 10) filling. The drops with good dispersibility and good stability are obtained by screening the prescription and optimizing the preparation process.