62 results about "Via bronchus" patented technology

The invention provides methods and apparatus for navigating a medical instrument to a target in the lung. In one embodiment, the invention includes inserting a bronchoscope into the lung, inserting a catheter into the lung through the working channel of the bronchoscope, inserting a tracked navigation instrument wire into the lung through the catheter, navigating the tracked navigation instrument through the lung to the target, advancing the catheter over the tracked navigation instrument to the target, removing the tracked navigation instrument from the catheter, and inserting a medical instrument into the catheter, thus bringing the medical instrument in proximity to the target.

Methods, devices, and systems are described herein that allow for improved sampling of tissue from remote sites in the body. A tissue sampling device comprises a handle allowing single hand operation. In one variation the tissue sampling device includes a blood vessel scanning means and tissue coring means to excise a histology sample from a target site free of blood vessels. The sampling device also includes an adjustable stop to control the depth of a needle penetration. The sampling device may be used through a working channel of a bronchoscope.

Systems, methods and devices for performing pulmonary procedures, and in particular treating lung disease. A flow control element includes a valve that prevents airflow in the inhalation direction but permits airflow in the exhalation direction. The flow control element is guided to and positioned at the site by a bronchoscope that is introduced into the patient's trachea and used to view the lungs during delivery of the flow control element. The valve may include one, two or more valve elements, and it may be collapsible for easier delivery. A source of vacuum or suction may be used to increase the amount of fluid withdrawn from the lung tissue. A device for measuring hollow structures, such as bronchioles, and a device for removing a previously-placed flow control element are disclosed as well.

Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and / or to induce collapse in one or more lung regions. An identified region of the lung is targeted for treatment, such as to modify the flow to the targeted lung region or to achieve volume reduction or collapse of the targeted lung region. The targeted lung region is then bronchially isolated to regulate airflow into and / or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region. The bronchial isolation of the targeted lung region is accomplished by implanting a flow control device into a bronchial passageway that feeds air to a targeted lung region.

Systems, methods and devices for performing pulmonary procedures, and in particular treating lung disease. A flow control element includes a valve that prevents airflow in the inhalation direction but permits airflow in the exhalation direction. The flow control element is guided to and positioned at the site by a bronchoscope that is introduced into the patient's trachea and used to view the lungs during delivery of the flow control element. The valve may include one, two or more valve elements, and it may be collapsible for easier delivery. A source of vacuum or suction may be used to increase the amount of fluid withdrawn from the lung tissue. A device for measuring hollow structures, such as bronchioles, and a device for removing a previously-placed flow control element are disclosed as well.

Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and / or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and / or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.

Methods and systems for lung volume reduction of a patient are described. The methods include implanting a flow control device in a bronchial passageway of the lung. The flow control device regulates fluid flow through the bronchial passageway and includes a valve protector that at least partially surrounds a valve member. The valve protector has sufficient rigidity to maintain the shape of the valve member against compression.

A desired fluid flow dynamic to a lung region can be achieved by deploying various combinations of flow control devices and bronchial isolation devices in one or more bronchial passageways that communicate with the lung region. The flow control devices are implanted in channels that are formed in the walls of bronchial passageways of the lung. The flow control devices regulate fluid flow through the channels. The bronchial isolation devices are implanted in lumens of bronchial passageways that communicate with the lung region in order to regulate fluid flow to and from the lung region through the bronchial passageways.

Methods, devices, and systems are described herein that allow for improved sampling of tissue from remote sites in the body. A tissue sampling device comprises a handle allowing single hand operation. In one variation the tissue sampling device includes a blood vessel scanning means and tissue coring means to excise a histology sample from a target site free of blood vessels. The sampling device also includes an adjustable stop to control the depth of a needle penetration. The sampling device may be used through a working channel of a bronchoscope.

Methods, devices, and systems are described herein that allow for improved sampling of tissue from remote sites in the body. A tissue sampling device comprises a handle allowing single hand operation. In one variation the tissue sampling device includes a blood vessel scanning means and tissue coring means to excise a histology sample from a target site free of blood vessels. The sampling device also includes an adjustable stop to control the depth of needle penetration. The sampling device may be used through a working channel of a bronchoscope.

The present invention provides an endotracheal intubation assist instrument for inserting the bronchofiberscope from the oral or nasal cavity to the trachea easily and then inserting the endotracheal tube into the trachea easily. The side hole 20 is installed near the front edge of the guide tube 10. The guide tube 10 advances naturally from the oral cavity, and the front edge of the guide tube 10 reaches the entrance of the esophagus. The view field is obtained by putting the front edge of the bronchofiberscope 200 onto the base 21. The glottis can be found by the view field of the bronchofiberscope 200 while pulling back the guide tube 10 slowly. The path for the bronchofiberscope 200 from the oral cavity to the esophagus can be secured by the guide tube 10 without influence of the obstacles such as a tongue and an epiglottis, and the operatability can be enhanced. Only the guide tube 10 is removed and the bronchofiberscope 200 remains as the guide line for the endotracheal tube insertion. The endotracheal tube is inserted to the trachea by utilizing the bronchofiberscope 200 as the guide line.

Methods and devices are adapted for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and / or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and / or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.

A retractable protective respiratory mask including disposable filters, which protects the respiratory system, covering the nose and mouth during inhalation while breathing in an atmosphere polluted by different agents, such as infectious, virulent, or pathogenic agents, or other toxic substances. The mask also protects non-infected persons from persons infected with a virus, as saliva and sputum expelled when coughing, breathing-out, and / or talking can be deposited inside the mask. The mask can include a collection-container filter, allowing a viral-infected wearer to breathe in a polluted atmosphere, to talk, to cough, to sneeze and / or to deposit saliva and sputum. The mask can be used as any other type of filter mask and / or disposable environmental air mask for industry in general, and also providing protection in rarefied natural atmospheres. The mask can be used as a container or packaging for drugs administered by means of bronchial airways, or as medical or rescue masks.

Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and / or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and / or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.

The invention discloses a visual automobile spray simulation training system and an application method thereof. The visual automobile spray simulation training system comprises a pneumatic spray pump,spray guns, spray templates and a computer terminal. The output end of the pneumatic spray pump is connected with an air circuit distributor through a main air pipe. The air circuit distributor is connected with a plurality of spray guns through branched air pipes, and the number of the spray templates corresponds to the number of the spray guns. Gravity sensors, ultrasonic sensors and laser ranging sensors are installed on the spray guns, the spraying angle, speed and distance of an automobile can be monitored and collected, and then data collected by the sensors is wirelessly transmitted tothe computer terminal for processing and analysis, so that the intelligent visual information management for trainees to participate in vehicle spraying training is realized. The visual automobile spray simulation training system and the application method thereof realize the intelligent visual information management for the spraying training process of each trainee.

The invention discloses a battery assembly. The battery assembly comprises a battery shell, and the top of an inner cavity of the shell is open and the inner wall is provided with a shock absorbing assembly. The shock absorbing assembly abuts against the inner and outer walls of a battery inner shell, and a battery is fixed into an inner cavity of the inner shell. The bottom of a heat dissipationgap communicates with one end of an air inlet pipe, and the top opening portion of the battery shell is assembled and sealed with a battery cover. The battery cover is provided with an exhaust pipe, and one end of the exhaust pipe communicates with the top of the heat dissipation gap. The inner cavity of the inner shell communicates with one end of a wire conduit, and the other end of the wire conduit penetrates out of the shell with the battery. An air blowpipe is fixed between heat dissipating protruding blocks, and the air blowpipe is provided with blow holes at the corresponding positionson both sides of the heat dissipation protruding blocks. One end of the air blowpipe communicates with a connecting pipe, and the other end of the air inlet pipe communicates with an exhaust port of avehicle-mounted air conditioner through a first air inlet pipe. The air inlet end of the vehicle-mounted air conditioner communicates with one of outlets of reversing air valves through a branch airpipe, and the connecting pipe communicates with one end of an air inlet manifold. The invention further discloses an electric vehicle to which the battery assembly is applied.

The invention discloses an efficient indoor air humidifier, which comprises a base, a heating device, a water tank, a steam chamber and an air pump. A heating device is installed on one side of the upper end of the base, a water tank is installed on the upper end of the heating device, and a water inlet is arranged on one side of the water tank. A steam chamber is installed on the upper end of the water tank, and the steam chamber and the water tank are separated by a partition. There are multiple steam outlets on the partition. One end of the steam chamber is provided with an air inlet. The steam chamber is connected to the air inlet pipe of the air pump through the first air pipe. The air pump is installed on the air pump mounting frame, and the air pump mounting frame is fixed on the base. The air outlet pipe of the air pump is connected to one end of the second air pipe. The second air pipe is provided with multiple bronchi. The base is equipped with a power supply, which is electrically connected to the air pump. By installing a heating device at the lower end of the water tank, the water in the water tank can be heated and evaporated, and the evaporated water vapor enters the steam chamber. Under the action of the air pump, the water vapor in the steam chamber is extracted and sprayed by the nozzle on the bronchus. into the air.

A closed suction set insertable (1) includes a tube body (10), a bronchoscope connector (20), a choke valve (30) and a bronchoscope socket (40). The bronchoscope connector (20) is installed on the tube body (10), and the choke valve (30) is plugged into an external port (201) of the bronchoscope connector (20), and the choke valve (30) has a flexible choke plate (31) with an end extended into the bronchoscope connector (20) and sealed with an end of the choke valve (30). The bronchoscope socket (40) includes an external sleeve (41) and an internal sleeve (42), and the internal sleeve (42) has an insert hole (420) for passing a bronchoscope (2).

A surgical system includes a bronchoscope, an extended working channel defining an elongated passageway and adapted to extend through the bronchoscope, and a valve in fluid communication with the passageway of the extended working channel. The surgical system further includes an elongated surgical instrument configured and dimensioned to be inserted through the extended working channel. During operation, a fluid is able to flow from the valve and through the extended working channel such that the fluid travels within an annular area surrounding the elongated surgical instrument positioned within the extended working channel.

The invention relates to a shoulder type inflatable cervical vertebra tractor. Two brackets are connected through a connecting shaft; the inner sides of the lower ends of the two brackets are provided with a cylinder lifting device respectively; the lower end of each cylinder lifting device are provided with a shoulder pad respectively; two cylinder devices are connected through a branch air pipe and a three-way joint respectively; the other end of the three-way joint is connected with a main air pipe; one end of the main air pipe is provided with an air relief valve; the air relief valve is connected with an air charging device; the upper ends of the two brackets are connected with a front traction belt and a rear traction belt through connecting belts for the traction belts respectively; the front traction belt and the rear traction belt are buckled through the connecting belts for the traction belt; an adjusting device is arranged above the two shoulder pads; the cylinder is driven by the air charging device to lift so as to drive the bracket to rise to fulfill the aim of traction. The tractor has the advantages of simple structure and convenient use.

Methods of modifying the rate of systemic absorption of a drug administered to a subject by a pulmonary route, the method comprising covalently conjugating a hydrophilic polymer to a drug, wherein the drug has a half-life of elimination from the lung of less than about 180 minutes, to form a drug-polymer conjugate, wherein the drug-polymer conjugate has a net hydrophilic character and a weight average molecular weight of from about 50 to about 20,000 Daltons, and wherein the half-life of elimination from the lung of the drug-polymer conjugate is at least about 1.5-fold greater than the half-life of elimination from the lung of the drug, wherein the half-life of elimination from the lung is measured by bronchoalveolar lavage followed by assaying residual lung material.

The invention discloses an immunity device for large-scale cattle breeding. The immunity device comprises an immunity chamber, a conveyer belt, a speed measuring radar, a controller and an aerosol immunity device, wherein fans are arranged on the inner walls on two sides of the immunity chamber; the blowing directions of the fans are oblique and upward; the fans, a speed change motor and the speedmeasuring radar are separately and electrically connected with the controller; the aerosol immunity device comprises an oil-free muting air compressor, an air cylinder, an air pressure balancing machine, an air pressure control assembly, a main air pipe, a plurality of quick tees and a plurality of spray nozzles; the oil-free muting air compressor is connected with the air pressure control assembly; the air pressure control assembly, the air pressure balancing machine and the quick tees are connected by the main air pipe; each quick tee is connected with the corresponding spray nozzle througha corresponding branch air pipe; the oil-free muting air compressor, the air cylinder, the air pressure control assembly and the air pressure balancing machine are mounted on the outer side wall of the immunity chamber; and the branch air pipes and the spray nozzles are mounted at the inner top of the immunity chamber. The invention discloses the immunity device for large-scale cattle breeding which is low in cost, easy to manufacture and high in practicality.

A model of systemic mold / Aspergillus infection in a profoundly immunocompromised host has been established in the beagle dog. The beagle was rendered immunosuppressed using a combination of total body irradiation and daily steroids, which provided a window of time where the mold could be successfully inoculated through a bronchoscope. This created a localized infection in one lung lobe, which subsequently spread diffusely throughout the lung parenchyma, and uniformly resulted in the animal's death. The invention contemplates the further study of the pathophysiology of opportunistic mold infections in vivo and also provides examples for the development of new antifungal agents and more effective combinations of agents. Finally, the invention contemplates the development of technology for the early detection of systemic mold infections. The inventors envision, that the use of the model should help save patients from clinical trials of antifungal drugs that may be effective in vitro without living up to the expectations in a clinical setting.

One aspect of the invention relates to a hydrogel comprising a polymer comprising a plurality of pendent hydroxyl groups, a crosslinker, and a sclerosing agent. Another aspect of the invention relates to a method for reducing lung volume in a patient comprising the steps of advancing into a region of a patient's lung via said patient's trachea a multi-lumen catheter lumen through a bronchoscope; and co-administering, through the multi-lumen catheter, a first mixture comprising a first amount of a polymer containing a plurality of pendent hydroxyl groups; a second mixture comprising a second amount of a crosslinker; and a third mixture comprising a third amount of a sclerosing agent; thereby forming a hydrogel in said region. In certain embodiments, the compositions and methods described herein are intended for use in the treatment of patients with emphysema of the lung.

A support system including a rail, a lower support, and an instrument support. The lower support is configured to receive a portion of a bronchoscope and to selectively fix the bronchoscope relative to the rail. The instrument support is slidably disposed on the rail and is selectively lockable to the rail. The instrument support is configured to releasably couple to a surgical instrument inserted through the bronchoscope to fix the position of a portion of the surgical instrument relative to the bronchoscope.

A system to alleviate a symptom of chronic obstructive pulmonary disease in a lung of a patient by providing a ventilation bypass pathway which allows air to exit the lung via the bronchus or trachea. The system includes a conduit connected by an airway connection device to an artificial opening through a wall of a region of a trachea or bronchus external to the lung. The other end of the conduit is connected by a lung connection device to an opening through a visceral membrane of the lung. A flow-control device such as a filter or valve is connected to the conduit to allow exhalation via the conduit but control flow from the airway to the lung. The conduit creates a direct fluid communication between the lung of the patient and the airway of the patient which permits air to exit the lung and enter the airway via the conduit.

The invention provides a sustained release microsphere carrying rifapentine and linezolid as well as a preparation method and applications of the sustained release microsphere. The sustained release microsphere contains rifapentine, linezolid and a medicinal carrier, wherein the medicinal carrier wraps rifapentine and linezolid, and the medicinal carrier is poly lactic-co-glycolic acid. The invention further provides the preparation method of the sustained release microsphere. The sustained release microsphere can treat pulmonary tuberculosis, especially, cavity tuberculosis through bronchoscope local administration; the problems that the existing medicines are poor in sustained release effect, the keeping time of the effective medicine concentration is short, and the compliance of patients is poor, are solved.