The invention discloses a pharmaceutical hard sheet cutting machine for polyvinyl chloride solid tablets. The hard sheet cutting machine includes a conveying assembly, and the conveying assembly includes a bottom bracket. The bottom bracket is equipped with a power roller, and the bottom bracket is also equipped with a Slitting shaft, feeding assembly is installed on one side of the conveying assembly, the feeding assembly includes feeding bottom support, an inclined support plate is provided on the feeding bottom support, a slide plate is installed on the inclined support plate, and a dust removal assembly is installed above the cutting shaft , the dust removal assembly includes a lower dust collection box, an upper dust collection box is arranged above the lower dust collection box, a slice assembly is provided on one side of the dust removal assembly, and a winding assembly is provided on the conveying assembly and the feeding assembly. The invention has practical functions, adopts sliding and tensioning discharge, has a simple structure, saves the structural design of the slitting machine, reduces the use cost, and has good dust removal effect. There are two sets of dust collection boxes on the upper and lower sides, which effectively solves the problem of floating dust and cutting. To deal with the problem of slag, there is a split component, which can automatically control the lifting, and solves the problem of winding and overlapping of the rewinding roll during rewinding.